A5027663552- Head and Neck Cancer Studies
- Advanced X-ray and CT Imaging
- Radiation Dose and Imaging
- Advanced Radiotherapy Techniques
- Cancer Diagnosis and Treatment
- Lung Cancer Research Studies
- Digital Radiography and Breast Imaging
- AI in cancer detection
- Medical Imaging Techniques and Applications
- Advances in Oncology and Radiotherapy
- Glioma Diagnosis and Treatment
- Lung Cancer Treatments and Mutations
- HER2/EGFR in Cancer Research
- Brain Metastases and Treatment
- Oral health in cancer treatment
- Lymphoma Diagnosis and Treatment
- Acute Ischemic Stroke Management
- Salivary Gland Tumors Diagnosis and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Breast Cancer Treatment Studies
- Ear and Head Tumors
- Cerebrovascular and Carotid Artery Diseases
- Cancer, Stress, Anesthesia, and Immune Response
- Microtubule and mitosis dynamics
- Retinoids in leukemia and cellular processes
Istituti di Ricovero e Cura a Carattere Scientifico
2019-2025
Policlinico San Matteo Fondazione
2019-2025
Ente Ospedaliero Ospedali Galliera
2022
University of Milan
2019-2021
Associazione Italiana Di Oncologia Medica
2002
National Cancer Research Institute
1993-2001
Alleanza Contro il Cancro
1991-2000
Virginia Commonwealth University Medical Center
1993
Ospedale Policlinico San Martino
1988-1990
For patients with advanced, unresectable squamous-cell carcinoma of the head and neck, radiotherapy is standard treatment but has poor results. We therefore designed a randomized trial to determine whether alternating chemotherapy would improve survival such patients.
Between 1983 and 1986, the National Institute for Cancer Research in Genoa affiliated institutions conducted a randomized study to compare two different ways of combining chemotherapy (CT) radiation therapy (RT). One hundred sixteen patients were receive neoadjuvant CT followed by definitive RT (treatment arm A) or alternating RT. In treatment A, consisted 70 Gy involved areas 50 uninvolved neck at 2 Gy/fraction, five fractions per week. B, 60 three courses 20 each, ten fractions/2 weeks...
Breast cancer is the most common tumor in women and represents leading cause of death. Radiation therapy plays a key-role treatment all breast stages. Therefore, adoption evidence-based treatments warranted, to ensure equity access standardization care clinical practice.This national document on highest available data was developed endorsed by Italian Association Clinical Oncology (AIRO) Cancer Group.We analyzed literature regarding radiation therapy, using SIGN (Scottish Intercollegiate...
The combination of chemotherapy and interferons has been tested in several human tumors but, until now, no clinical data have reported head neck cancer. At the Istituto Nazionale per la Ricerca sul Cancro Genoa, 14 patients with previously treated SCC-HN underwent following regimen: cisplatin, 20 mg/m2/day, 5-fluorouracil, 200 mg/m2/day i.v. bolus recombinant interferon-alpha-2b (r-IFN-alpha-2b) (Intron-A, Shering-Plough), 3 MIU/day i.m., for 5 consecutive days. Recombinant IFN-alpha-2b was...
The administration of granulocyte-monocyte colony stimulating factor (GM-CSF) should allow an increase in the doses chemotherapy for patients with advanced cancers head and neck.Eleven histologically proven relapsed squamous cell carcinoma neck entered this Phase I study based on combination cisplatin (20 mg/m2/day 5 days), escalating 5-fluorouracil, both given by intravenous injection from day 1 to 5, GM-CSF, micrograms/kg 8 19.The maximum tolerated 5-fluorouracil dosage was 300 mg/m2 i.v....
Background The increasing complexity of management strategies for patients with head and neck squamous cell carcinoma (HN-SCC) calls the investigation new objective prognostic parameters to subdivide according tumor's biological aggressiveness. Methods We evaluated in 35 HN-SCC pretreatment kinetics DNA ploidy after vivo infusion bromodeoxyuridine flow cytometric analysis. Patients were treated radical surgery followed by conventional radiation therapy. Locoregional control data are...