- Cardiac electrophysiology and arrhythmias
- ECG Monitoring and Analysis
- Cardiac Arrhythmias and Treatments
- Cardiac pacing and defibrillation studies
- Atrial Fibrillation Management and Outcomes
- Cancer Immunotherapy and Biomarkers
- Long-Term Effects of COVID-19
- Pancreatic and Hepatic Oncology Research
- Cancer Genomics and Diagnostics
- Cardiovascular Effects of Exercise
- Health Systems, Economic Evaluations, Quality of Life
- Metal-Organic Frameworks: Synthesis and Applications
- Metabolism and Genetic Disorders
- Neurological and metabolic disorders
- Phonocardiography and Auscultation Techniques
- Conducting polymers and applications
- Mathematical and Theoretical Epidemiology and Ecology Models
- Cervical and Thoracic Myelopathy
- Infant Nutrition and Health
- Stochastic processes and financial applications
- Neonatal Respiratory Health Research
- Heart Failure Treatment and Management
- Regulation of Appetite and Obesity
- Stochastic processes and statistical mechanics
- Psychosomatic Disorders and Their Treatments
LMU Klinikum
2018-2025
German Centre for Cardiovascular Research
2023-2025
Ludwig-Maximilians-Universität München
2018-2025
Medical University of South Carolina
2020
Heart failure and cardiac decompensation, often leading to recurrent hospitalizations, significantly impair quality of life expectancy. Monitoring hydration status is crucial in managing these patients. Although body impedance analysis (BIA) a simple, cost-effective, noninvasive method, its clinical application remains underutilized worldwide. Given potential improve therapy management, this study aimed evaluate the feasibility repetitive BIA measurements patients hospitalized for acute...
Background: Long‐COVID has attracted increased attention with rising numbers of affected patients and high individual symptom burden. Prior studies have described its prevalence, course disease, severity. Yet, the influence intensive care, including telemedical support for at risk a severe initial COVID‐19 on occurrence associated symptoms is studied to lesser extent. Methods: Here, we report long‐term results COVID‐SMART study, which randomized at‐risk either smartwatch‐based monitoring or...
Abstract Growth and nutrition in preterm infants have long‐term implications for neurodevelopmental cardiometabolic outcomes. Many are discharged from the neonatal intensive care unit (NICU) with growth restriction, but often without a specialized team to monitor postdischarge growth. At our institution, we addressed ongoing concerns health of these post‐discharge by creating Nutrition NICU Graduate Clinic. This clinic serves who were born very low birth weight, had difficulty growing or...
This pilot study aimed on generating insight alterations in circulating immune cells during the use of FOLFIRINOX and gemcitabine/nab-paclitaxel pancreatic ductal adenocarcinoma (PDAC). Peripheral blood mononuclear were isolated before 30 days after initiation chemotherapy from 20 patients with advanced PDAC. Regulatory T (FoxP3+) checkpoints (PD-1 TIM-3) analyzed by flow cytometry immunological changes correlated clinical outcome. Heterogeneous observed T-cell subpopulations a pronounced...
Background COVID-19 remains a challenge to individual health and healthcare resources worldwide. Telemedical surveillance might minimise hospitalisation direct patient–physician contacts. Yet, randomised clinical trials evaluating telemedical management of patients are lacking. Methods COVID-SMART is randomised, open-label, controlled trial investigating whether telemedicine reduces the primary end-point or any unscheduled utilisation an emergency medical service within 30 days follow-up....
Treatment with wearable cardioverter defibrillators (WCD) is a non-invasive, transient therapy option for prevention of sudden cardiac death (SCD) in patients temporary contraindications implantation permanent defibrillator. Due to the constant risk fatal arrhythmias, compliance fundamental requirement effectiveness WCD, but this might be hindered by poor quality-of-life (QoL) during WCD therapy. In retrospective single-center study, we examined if standardized training and adherence...
Postmortal interrogation of cardiac implantable electrical devices (CIED) may contribute to the determination time death in forensic medicine. Recent studies aimed improve estimation by combining findings from autopsy, CIED and patients´ medical history. deceased undergoing autopsy were included, if remained unclear after assessment. explanted with known analysed as a control cohort. sent our device lab underwent analysis blinded for findings, history police reports. The accuracy cohort...
Zieve syndrome is a rare condition which occurs in patients with severe alcohol abuse. It typically characterised by the triad of jaundice, haemolytic anaemia and transient hyperlipidaemia. In following report, we present case man his 30s who was admitted to our emergency department epigastric pain signs intoxication. Blood samples showed hyperlipidaemia jaundice. Due massive hyperlipidaemia, laboratory measurements triglycerides were impaired blood had ‘yellowish’ ‘creamy’ texture. order...
Abstract Background Correct interpretation of ECG recordings plays a crucial role in cardiology. are performed immediately order to guide treatment patients with suspected acute coronary syndrome (ACS). Non-cardiologists usually rely on automated manufacturer-derived interpretation. The main purpose these methods is detect lifethreatening patterns high sensitivity, at cost specificity. However, as yet, the accuracy automatic annotations has not been tested investigator-initiated (IIT)...
Abstract Background Periodic repolarization dynamics (PRD) is an electrocardiographic marker that quantifies sympathetic-activity associated instabilities of cardiac repolarization. PRD a strong predictor mortality in patients with ischemic (ICM) and non-ischemic cardiomyopathy (NICM) has been proposed to identify who benefit from prophylactic ICD implantation. Purpose To conduct systematic review meta-analysis concerning the prognostic value for predicting all-cause relation...
Abstract Background Assessing lactate (LT) or anaerobic thresholds (AT) in athletes is an important tool to control training intensities and estimate individual performance levels. Previously we demonstrated that ECG-based assessment of cardiac repolarization instability during exercise testing allows non-invasive estimation AT recreational athletes. Here, validate this method professional amateur team sports Methods We included 65 (32 professionals 33 athletes; 51 men, 14 women, mean age...
Abstract Background Periodic repolarization dynamics (PRD) is an electrocardiographic biomarker that quantifies low-frequency (LF), sympathetic-activity associated instabilities of repolarization. PRD a strong predictor mortality in patients after myocardial infarction (MI). The main limitation the requirement ECGs with duration ≥20 minutes. Calculation using 10-second would be advantageous allowing implementation everyday clinical practice. Purpose We aimed to develop and validate modified...
An elderly patient with a history of atrial fibrillation presented to our emergency room. Previous medical records from another hospital described pacemaker lead in the echocardiography although had no known implantation. Finally, by close examination, chest X-ray, and computed tomography, we found that kyphoplasty spine caused so-called palacos embolism, which repeatedly been mistaken for lead. Unusually, there were further signs material pulmonary veins. As was asymptomatic embolism only...