- Psoriasis: Treatment and Pathogenesis
- Rheumatoid Arthritis Research and Therapies
- Spondyloarthritis Studies and Treatments
- Psychological Well-being and Life Satisfaction
- Autoimmune and Inflammatory Disorders Research
- Mental Health Research Topics
- Italian Social Issues and Migration
- Aging and Gerontology Research
- Regional resilience and development
- Cancer-related molecular mechanisms research
- Biosimilars and Bioanalytical Methods
- Renal Diseases and Glomerulopathies
- Chronic Lymphocytic Leukemia Research
- Ocular Diseases and Behçet’s Syndrome
- Extracellular vesicles in disease
- Socioeconomic and Demographic Analysis
- Socio-economic Development and Sustainability
- Employment and Welfare Studies
- Migration, Aging, and Tourism Studies
- Mycobacterium research and diagnosis
- Sensory Analysis and Statistical Methods
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Chemistry and Chemical Engineering
- Sustainable Development and Environmental Policy
- Aging, Elder Care, and Social Issues
University of Rome Tor Vergata
2021-2025
Istituto Nazionale di Statistica
2019-2024
Sapienza University of Rome
2019
To assess any differences and similarities in psoriatic arthritis (PsA) between sexes. Any possible of psoriasis its potential impact on disease burden sexes with PsA were also evaluated.Cross-sectional analysis two longitudinal cohorts. The the PtGA was evaluated. Patients stratified four groups based BSA. median then compared groups. Moreover, a multivariate linear regression performed order to evaluate associations skin involvement, split by sexes.We enrolled 141 males 131 females: PtGA,...
Interstitial lung disease (ILD) is a common extra-articular manifestation of rheumatoid arthritis (RA). The inflammatory response in characterized by severe oxidative stress, which enhances cellular senescence. Telomeric shortening and mitochondria dysregulation represent two hallmarks maintenance telomere length (TL) mitochondrial DNA (mtDNA) copy number preserved many proteins, such as TERF1 TFAM, respectively. Our aim was to evaluate the TL, mtDNA expression regulator gene factors RA...
In this prospective observational study, data were collected from 34 rheumatology clinics in Italy patients with rheumatoid arthritis (RA), psoriatic (PsA) and axial spondyloarthritis (axSpA) who started golimumab (GLM) as a second anti-TNFα drug. The primary objective was to evaluate the effectiveness of GLM after 6 months. Changes quality life using EQ-5D-5L also assessed. A total 194 aged 53.2 ± 12 years anti-TNF drug: 39 (20.1%) RA, 91 (46.9%) PsA 64 (32.9%) axSpA. After months...
Background Rheumatoid Arthritis (RA) is a chronic inflammatory disease with heterogeneous treatments’ clinical response. Goals of treatment are remission and low activity, which not achieved in all patients despite the introduction early treat to target strategy. Objective To investigate causes disease-modifying antirheumatic drugs (DMARDs) discontinuation failure multiple for inefficacy, identify possible predictors’ according RA patient characteristics real-world setting. Methods 718 were...
We aimed to identify an expression profile of lncRNAs potentially related treatment response in Psoriatic arthritis (PsA) patients, be used as potential genomic biomarkers predictors drug effectiveness. In addition, we evaluated a possible association between genetic variants and the therapy using clinical parameter Disease Activity Index. For study, collected 48 treated PsA monitoring for 12 months. initially PCR Array and, then, validated results with qRT-PCR. also retrospectively...
The aim of this work is to characterize which Minimal Disease Activity (MDA) domains are mainly achieved, based on different treatments, in psoriatic arthritis (PsA) patients. Moreover, the association between MDA achievement and treatment groups was assessed. We conducted a cross-sectional analysis two longitudinal PsA groups. Inclusion criteria were: age ≥ 18 years, diagnosis, stable for at least 6 months. Patients were grouped depending therapy: group 1: Non-Steroidal Anti-Inflammatory...
Unaccompanied Migrant Minors (UMM) are, perhaps, the most vulnerable among migrants arriving in Europe. That requires institutions to guarantee their safety and adequate reception policies. Since 2012, presence Italy has more than quadrupled, raising 23 thousand UMMs at end of 2023. During same year, several regulatory interventions were promulgated involving UMMs’ placement. This paper analyses demographic characteristics, migratory trajectories, modes arrival, placement permanence present...