A5018593082- Rheumatoid Arthritis Research and Therapies
- Systemic Sclerosis and Related Diseases
- Bone health and treatments
- Bone Metabolism and Diseases
- Spondyloarthritis Studies and Treatments
- Autoimmune and Inflammatory Disorders Research
- Systemic Lupus Erythematosus Research
- Bone health and osteoporosis research
- Vitamin D Research Studies
- Glaucoma and retinal disorders
- Bone and Joint Diseases
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Cytokine Signaling Pathways and Interactions
- Dermatologic Treatments and Research
- Psoriasis: Treatment and Pathogenesis
- Pulmonary Hypertension Research and Treatments
- Retinal Diseases and Treatments
- Inflammatory Myopathies and Dermatomyositis
- Osteoarthritis Treatment and Mechanisms
- Estrogen and related hormone effects
- Skin Diseases and Diabetes
- Angiogenesis and VEGF in Cancer
- Inflammatory mediators and NSAID effects
- Urticaria and Related Conditions
- Growth Hormone and Insulin-like Growth Factors
University of Foggia
2016-2025
Ospedali Riuniti di Foggia
2011-2024
University of Genoa
2024
University of Verona
2022
Royal Hallamshire Hospital
2021
Sheffield Teaching Hospitals NHS Foundation Trust
2021
University of Bari Aldo Moro
1998-2016
Foundation for Human Potential
2016
Presidio Ospedaliero
2011
Marche Polytechnic University
1995
Objectives To assess the effects of Rituximab (RTX) on skin and lung fibrosis in patients with systemic sclerosis (SSc) belonging to European Scleroderma Trial Research (EUSTAR) cohort using a nested case-control design. Methods Inclusion criteria were fulfilment American College Rheumatology classification for SSc, treatment RTX availability follow-up data. RTX-treated matched control from EUSTAR database not treated RTX. Matching parameters skin/lung modified Rodnan Skin Score (mRSS),...
Background The inflammatory contribution to type 2 diabetes (T2D) has suggested new therapeutic targets using biologic drugs designed for rheumatoid arthritis (RA). On this basis, we aimed at investigating whether interleukin-1 (IL-1) inhibition with anakinra, a recombinant human IL-1 receptor antagonist, could improve both glycaemic and parameters in participants RA T2D compared tumour necrosis factor (TNF) inhibitors (TNFis). Methods findings This study, as multicentre, open-label,...
Abstract The aim of this study was to examine the relationship between visual field (VF) loss, vision-related quality life (QoL) and glaucoma-related symptoms in a large cohort primary open angle glaucoma (POAG) patients. POAG patients with or without VF defects “glaucoma suspect” were considered eligible. QoL assessed using validated versions 25-item National Eye Institute Visual Function Questionnaire (NEI-VFQ-25) Glaucoma Symptom Scale (GSS). Patients classified as having damage one eye...
Rheumatoid arthritis (RA) is associated with an increased risk of morbidity and mortality, when compared general population, largely due to enhanced atherosclerotic disease. In this work, we aimed at assessing both occurrence predictive factors subclinical clinical atherosclerosis in RA. From January 1, 2015, December 31, consecutive participants RA, admitted Italian Rheumatology Units, were assessed the GIRRCS (Gruppo Italiano di Ricerca Reumatologia Clinica e Sperimentale) cohort. After...
Abstract Background Adult-onset Still’s disease (AOSD) is a systemic inflammatory disorder of unknown aetiology usually affecting young adults. Interestingly, recent evidence from the juvenile counterpart AOSD suggested emergent high fatality rate lung (LD) in these patients. In this work, we aimed to characterise LD AOSD, identify associated clinical features and predictive factors, describe long-term outcomes comparing patients with those without. Methods A retrospective assessment...
Objective To assess the predictive role of ferritin and C-reactive protein (CRP) on occurrence macrophage activation syndrome (MAS) mortality in patients with adult onset Still's disease (AOSD), a rare severe disease, included multicentre Gruppo Italiano di Ricerca Reumatologia Clinica e Sperimentale (GIRRCS) cohort. Methods The role, at time diagnosis, serum levels CRP MAS mortality, was evaluated by logistic regression analyses receiver-operating characteristic (ROC) curves were built to...