A5066931776- Systemic Sclerosis and Related Diseases
- Rheumatoid Arthritis Research and Therapies
- Bone health and treatments
- Bone Metabolism and Diseases
- Spondyloarthritis Studies and Treatments
- Systemic Lupus Erythematosus Research
- Bone health and osteoporosis research
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Bone and Joint Diseases
- Vitamin D Research Studies
- Pulmonary Hypertension Research and Treatments
- Cytokine Signaling Pathways and Interactions
- Autoimmune and Inflammatory Disorders Research
- Inflammatory Myopathies and Dermatomyositis
- Psoriasis: Treatment and Pathogenesis
- Osteoarthritis Treatment and Mechanisms
- Pregnancy and Medication Impact
- Connective Tissue Growth Factor Research
- Medical Imaging and Pathology Studies
- Connective tissue disorders research
- Angiogenesis and VEGF in Cancer
- Inflammasome and immune disorders
- Dermatological and Skeletal Disorders
- Radiopharmaceutical Chemistry and Applications
- Fibromyalgia and Chronic Fatigue Syndrome Research
University of Foggia
2016-2025
Ospedali Riuniti di Foggia
2011-2024
Instituto Português de Reumatologia
2022
Instituto Português de Malacologia
2022
University of Bari Aldo Moro
2002-2018
Foundation for Human Potential
2016
University of Padua
1997-2014
Ospedale Pediatrico Giovanni XXIII
2011
Hôpital Lariboisière
2004
Inserm
2004
Abstract Psoriatic arthritis (PsA) is an inflammatory joint disease, characterized by extensive bone resorption, whose mechanisms have not been fully elucidated. Thus, in the present study we investigated involvement of RANKL, TNFα, and IL‐7 osteoclastogenesis PsA patients. In vitro models, consisting unfractionated T‐cell‐depleted mononuclear cells from peripheral blood (PBMCs) synovial fluid (SFMCs) 20 patients as well healthy donors were studied. Freshly isolated T B PBMCs fibroblasts...
An increased risk of developing severe infections has been evidenced in rheumatic disease (RD) patients, and anti-COVID-19 vaccination is strictly recommended for RD patients. However, up to now, no data are available on safety, immunogenicity efficacy COVID-19 vaccinations The possible development adverse events (AEs), including the flare-up underlying RD, represents a matter growing importance. aim our study assess, safety profile different types approved vaccines influence...
Objective. To evaluate the expression of Dickkopf-1 protein factor (DKK-1), DKK-2, and β-catenin, components Wnt pathway, in human osteoarthritic (OA) osteoporotic (OP) osteoblasts to correlate it cell metabolic activity, proliferation, receptor activator nuclear factor-κB ligand/osteoprotegerin (RANKL/OPG) expression. Methods. Primary osteoblast cultures were obtained from healthy, OA, OP donors. In each population we evaluated DKK-1, nonphosphorylated β-catenin RANKL/OPG expression,...
Background: Randomized clinical trials have demonstrated the efficacy of secukinumab (SECU) in reducing disease activity psoriatic arthritis (PsA), while real-world studies prove a broader perspective on SECU’s usefulness everyday practice. Objectives: To assess effectiveness SECU by evaluating drug survival and identifying potential predictors response treatment discontinuation patients with moderate-to-severe PsA, using data from Italian Group for Study Early Arthritis (GISEA) registry....