A5101487427- Algorithms and Data Compression
- Cancer-related molecular mechanisms research
- Circular RNAs in diseases
- MicroRNA in disease regulation
- Genomics and Phylogenetic Studies
- Advanced Malware Detection Techniques
- DNA and Biological Computing
- Software Testing and Debugging Techniques
- Photosynthetic Processes and Mechanisms
- Software Engineering Research
- Web Data Mining and Analysis
- Glycosylation and Glycoproteins Research
- Insect Utilization and Effects
- Mobile and Web Applications
- Redox biology and oxidative stress
- Plant and Fungal Species Descriptions
- Molecular Biology Techniques and Applications
- Plant Diversity and Evolution
- Insect and Arachnid Ecology and Behavior
- Iron Metabolism and Disorders
- Angiogenesis and VEGF in Cancer
- Cancer, Hypoxia, and Metabolism
- Advanced Software Engineering Methodologies
- TGF-β signaling in diseases
- Protease and Inhibitor Mechanisms
Hubei University of Medicine
2023-2024
Taihe Hospital
2023-2024
Monash University
2020-2021
Shantou University
2019
Shantou University Medical College
2019
Qingdao University
2018
Affiliated Hospital of Qingdao University
2018
Xiamen University
2017
KTH Royal Institute of Technology
2014-2017
Beijing Normal University
2011
MicroRNAs are important gene regulators that potentially play a profound role in tumorigenesis. Increasing evidence indicates miR-145 is tumor suppressor capable of inhibiting breast and colon cancer cell growth both vitro vivo. However, the biological function non-small lung (NSCLC) largely unknown. In cells, c-Myc confirmed direct target for miR-145. The aim this work was to investigate effect on proliferation NSCLC using lines A549 H23 as models. We determined expression level tissues...
Heparanase is an endo‐β‐ d ‐glucuronidase that cleaves heparan sulfate (HS) side chains of proteoglycans. Compelling evidence tie heparanase levels with all steps tumor formation including initiation, growth, metastasis and chemo‐resistance, likely involving augmentation signaling pathways gene transcription. In order to reveal the molecular mechanism(s) underlying protumorigenic properties heparanase, we established inducible (Tet‐on) system in U87 human glioma cells applied array...
Long non-coding RNA antisense in the INK4 locus (ANRIL) has been reported to promote tumorigenesis via regulating microRNA (miR)-99a gastric cancer cells. However, role of each component involved it is still not well understood. This study aimed verify ANRIL as underlying mechanisms. levels clinical tissues and cell lines were tested by qPCR. Effects silence on viability, migration invasion, apoptosis, miR-99a expression MKN-45 SGC-7901 cells measured using CCK-8, Transwell assay, flow...
It is critical for research to have an open, well-curated, representative set of apps analysis. We present a collection open-source Android collected from several sources, including Github. Our dataset, AndroZooOpen, currently contains over 45,000 app artefacts, picture Github-hosted apps. For released on Google Play, metadata categories, ratings and user reviews, are also stored. share this new dataset as part our ongoing better support enable topics involving artefact analysis, supplement...
With over 500,000 commits and more than 700 contributors, the Android platform is undoubtedly one of largest industrial-scale software projects. This project provides widely known API, which facilitates development apps. Unfortunately, because its API evolve at an extremely rapid pace, app developers need to continually monitor changes avoid compatibility issues in their apps (i.e do not work as expected when running on new version API). Despite a large number studies research community has...
Sequence analysis plays extremely important role in bioinformatics, and most applications of which have compute intensive kernels consuming over 70% total execution time. By exploiting the stages popular sequence applications, we present evaluate a VLSI architecture with focus on those that target at biological sequences directly, including pairwise alignment, multiple database search, short read mappings. Based coarse grained reconfigurable array propose use many-core 3D-stacked...
Rapidly developing Next Generation Sequencing technologies produce huge amounts of short reads that consisting randomly fragmented DNA base pair strings. Assembling those poses a challenge on the mapping to reference genome in terms both sensitivity and execution time. In this paper, we propose customized many-core hardware acceleration platform for read problems based hash-index method. The processing core is highly suite 2-hit string matching banded Smith-Waterman sequence alignment...
Recent studies show that deployed deep learning (DL) models such as those of Tensor Flow Lite (TFLite) can be easily extracted from real-world applications and devices by attackers to generate many kinds attacks like adversarial attacks. Although securing on-device DL has gained increasing attention, no existing methods fully prevent the aforementioned threats. Traditional software protection techniques have been widely explored, if implemented using pure code, C++, it will open possibility...
Abstract Cutaneous squamous cell carcinoma (CSCC) is the most common metastatic skin cancer. Circular RNAs (circRNAs) are differentially expressed in CSCC and can sequester sponge microRNAs. GSE74758 shows that hsa_circ_0001402 (circ_0001402) overexpressed circRNA CSCC. Expression of circ_0001402, microRNA(miR)‐625‐5p karyopherin subunit alpha 4 (KPNA4) was detected by quantitative real‐time polymerase chain reaction and/or Western blot. Colon formation, flow cytometry, Transwell assays...
To investigate the efficacy of Ciji Hua'ai Baosheng formula (CHBF) on microvessel density (MVD) and vascular endothelial growth factor (VEGF), kinase insert domain-containing receptor (KDR) basic fibroblast (bFGF) expression in serum tumor tissue mice receiving chemotherapy for treatment H(22) hepatocellular carcinoma.Sixty Kunming were injected subcutaneously with hepatoma carcinoma cell suspensions into right anterior armpit. Seven days later, all transplanted formed intraperitoneally 200...
Sequence analysis plays critical role in bioinformatics, and most applications of which have compute intensive kernels consuming over 70% total execution time. By exploiting the stages popular sequence applications, we present evaluate a VLSI architecture with focus on those that target at biological sequences directly, including pairwise alignment, multiple database search, short read mappings. Based coarse grained reconfigurable array (CGRA) propose use many-core 3D-stacked technologies to...
Next Generation Sequencing technologies produce huge amounts of short reads consisting randomly fragmented DNA base pair strings, while assembling poses a challenge on the mapping to reference genome in terms both sensitivity and execution time. In this paper, we propose many-core hardware acceleration platform for read based hash-index method, which benefit from distributed memory interface with 3D-stacked architecture local access. Our design provides an amazingly 45012 times speedup over...
The load model has an important influence on power system stability, while load's characteristics such as diversity, complexity and time-varying would lead to uncertainty of parameters.