A5015552990- Advanced Radiotherapy Techniques
- Cancer-related molecular mechanisms research
- Spacecraft and Cryogenic Technologies
- MicroRNA in disease regulation
- Opportunistic and Delay-Tolerant Networks
- Radiation Therapy and Dosimetry
- Circular RNAs in diseases
- RNA modifications and cancer
- Caching and Content Delivery
- Mobile Ad Hoc Networks
- Medical Imaging Techniques and Applications
- Liver Disease and Transplantation
- Organ Transplantation Techniques and Outcomes
- Pancreatic and Hepatic Oncology Research
- Hepatocellular Carcinoma Treatment and Prognosis
- Lung Cancer Diagnosis and Treatment
- Cryptography and Data Security
- Gastrointestinal Tumor Research and Treatment
- Radiation Dose and Imaging
- Pancreatitis Pathology and Treatment
- Membrane Separation Technologies
- Neuroendocrine Tumor Research Advances
- Oil, Gas, and Environmental Issues
- Privacy-Preserving Technologies in Data
- Head and Neck Cancer Studies
Jiangsu University of Science and Technology
2021-2025
Harbin University
2025
Chongqing Medical University
2020-2023
Xi'an Jiaotong University
2022-2023
The Affiliated Yongchuan Hospital of Chongqing Medical University
2020-2023
Zhengzhou University
2011-2022
Changshu Institute of Technology
2019-2022
University of Electronic Science and Technology of China
2021
Henan Cancer Hospital
2011-2020
Henan Provincial People's Hospital
2008-2018
Currently, the prognosis of patients with non-small cell lung cancer (NSCLC) remains dismal; hence, it is critical to identify effective anti-NSCLC agents limited side effects. This study aimed evaluate therapeutic potential flavonoid compound vitexin in human NSCLC cells and underlying mechanisms.The experimental results indicated that reduced viability A549 a dose-dependent manner nearly no toxicity against normal bronchial epithelial 16HBE cells. Vitexin also dose-dependently increased...
MicroRNAs (miRNAs) have been reported to play critical roles in tumor progression including hepatocellular carcinoma (HCC). Thus, the underlying mechanisms need further investigation. Previous study that loss of miR-345 expression indicated a poor prognosis HCC patients. This evaluated whether could promote metastasis and epithelial-mesenchymal-transition (EMT) by targeting interferon regulatory factor 1 (IRF1)-mediated mTOR/STAT3/AKT signaling. Underexpression was identified 65 cases human...
The natural gas (NG) liquefaction process utilizing the airfoil-finned microchannel printed circuit heat exchanger (PCHE) undergoes substantial internal structural changes due to extreme conditions of high pressure and large temperature differentials. induce both compressive thermal stresses within PCHE, which will compromise inherent stability transfer core. Moreover, distinctive streamlined structure fin arrangement render conventional stress analysis methods inadequate. In this paper,...
Compare the effects of high-intensity interval training (HIIT) and moderate-intensity continuous (MICT) on metabolic dysfunction-associated steatotic liver disease (MASLD), focusing mechanisms by which these two exercise modalities influence gut microbiota structure, bile acid metabolism, intestinal barrier function, as well their regulatory roles in hepatic lipid synthesis oxidative dynamics. Explore synergistic exercise-mediated mitochondrial fusion remodeling leptin signaling, elucidate...
MicroRNAs (miRNAs) play key roles in tumor development and progression. The aim of this study was to explore the expression levels miR-34a miR-217 hepatocellular carcinoma (HCC) further investigate clinicopathological prognostic value miR-217.The were evaluated using quantitative real-time PCR (qRT-PCR). Associations between these miRNAs features analyzed. Survival rate determined with Kaplan-Meier statistically analyzed log-rank method groups.We found that significantly downregulated HCC...
SUMOylation and deSUMOylation are dynamic mechanisms regulating a spectrum of protein activities. The SUMO proteases (SENP) remove conjugate from proteins, their expression is deregulated in cancers. SENP2 has been reported to play critical role the control hepatocellular carcinoma (HCC) cell growth by modulating stability β-catenin. However, underlying mechanism remains largely unknown. Here, we show that WW domain-containing oxidoreductase (WWOX), novel inhibitor Wnt/β-catenin pathway,...
This study aimed to investigate the key transcription factors (TFs), long noncoding RNAs (lncRNAs), and microRNAs (miRNAs) associated with hepatocellular carcinoma (HCC).The datasets GSE31383 GSE54238 were downloaded from Gene Expression Omnibus data repository. was used screen differentially expressed miRNAs, messenger (mRNAs) lncRNAs. ChipBase identify TF-miRNA pairs. StarBase selected miRNA-mRNA lncRNA-miRNA interactions. Kyoto Encyclopedia of Genes Genomes pathway analysis also conducted...
Long noncoding RNA X inactivate-specific transcript (lncRNA XIST) has been identified to contribute the development and progression of non-small cell lung cancer (NSCLC). Thus, it is important explore more specific functions molecular mechanisms XIST in NSCLC tumorigenesis.The expression XIST, microRNA (miR)-142-5p paired box 6 (PAX6) was measured using quantitative real-time polymerase chain reaction or Western blot, respectively. Cell proliferation analyzed counting kit-8 (CCK-8) assay....
Background While chemo-radiotherapy improves local control in patients with locally advanced rectal cancer, it can also increase acute hematological toxicity (HT), which leads to poor outcomes. Patients receiving bone marrow radiation have been shown develop HT. However, the safety and efficacy of sparing is undetermined. The aim our study was explore feasible dosimetric constraints for pelvic (PBM) that be widely used cancer undergoing chemo-radiotherapy. Methods 112 were selected divided...
The purpose of this study is to evaluate the sensitivities 3D diode arrays setup error for patient‐specific quality assurance (QA) volumetric‐modulated arc therapy (VMAT). Translational errors , and mm in RL, SI, AP directions rotational pitch, roll, yaw were set up two phantom systems, ArcCHECK with VMAT plans 11 patients. Cone‐beam computed tomography (CBCT) followed by automatic correction using a HexaPOD 6D treatment couch ensured position accuracy. Dose distributions phantoms compared...
Long non-coding RNA (lncRNA) X inactive specific transcript (XIST) has been identified as an oncogenic lncRNA in a series of human cancers, including esophageal squamous cell carcinoma (ESCC). In this study, we aimed to further explore the underlying mechanism XIST on ESCC progression. qRT-PCR assay was used determine levels and miR-129-5p. Western blot analysis performed assess cyclin D1 (CCND1) expression. Bioinformatic using starBase v2.0 software. Dual-luciferase reporter...
In view of Chua's circuit's characters and the deficient in DES algorithm, paper presents a new image encryption scheme based on algorithm chaotic encryption. The sequence is implemented to improve initial keys iterating operations, so that combined with algorithm. Theory analysis simulation results show presented can expand key space, security anti-attack ability effectively. It more propitious information transmission as this insures confidentiality information.
Aim: Small single-stranded non-coding RNAs (miRNAs) play an important role in carcinogenesis through degrading target mRNAs. However, the diagnostic value of miRNAs was not explored lung cancers. In this study, a support-vector-machine (SVM) model for diagnosis cancer established based on plasma biomarkers, clinical symptoms and epidemiology material. Methods: The expressions miRNA were examined with SYBR Green-based quantitative real-time PCR. Results: We identified that 10 (miR-21,...
Background Budd-Chiari syndrome (BCS) is characterized by liver sinusoidal congestion, ischemic cell damage, and portal hypertension caused hepatic venous outflow constriction. The aim of this research was to investigate the clinicopathological features BCS-associated hepatocellular carcinoma (HCC) explore its surgical treatment prognosis. Methods Clinical data from 38 patients with HCC who were surgically treated in our hospital July 1998 August 2010 retrospectively analyzed. prognosis for...
Abstract Purpose To accomplish the 3D dose verification to IMRT plan by incorporating DVH information and gamma passing rates (GPs) (DVH_GPs) so as better correlate patient‐specific quality assurance (QA) results with clinically relevant metrics. Materials methods DVH_GPs analysis was performed specific structures of 51 intensity‐modulated radiotherapy (IMRT) treatment plans (17 each for oropharyngeal neoplasm, esophageal cervical neoplasm) Delta4 system. Based on action levels 5% GPs 90%...