A5100724575- Air Quality and Health Impacts
- Telomeres, Telomerase, and Senescence
- Effects and risks of endocrine disrupting chemicals
- Birth, Development, and Health
- Climate Change and Health Impacts
- Nutrition and Health in Aging
- Allergic Rhinitis and Sensitization
- Gestational Diabetes Research and Management
- Marine and environmental studies
- Marine Invertebrate Physiology and Ecology
- Cancer-related molecular mechanisms research
- Health, Environment, Cognitive Aging
- Asthma and respiratory diseases
- Per- and polyfluoroalkyl substances research
- Research in Cotton Cultivation
- Toxic Organic Pollutants Impact
- Circular RNAs in diseases
- Gut microbiota and health
- Pregnancy and preeclampsia studies
- Ruminant Nutrition and Digestive Physiology
- Carcinogens and Genotoxicity Assessment
- MicroRNA in disease regulation
- Isotope Analysis in Ecology
- Heme Oxygenase-1 and Carbon Monoxide
- Sinusitis and nasal conditions
Zhengzhou University
2016-2025
Northeast Agricultural University
2013-2025
Peking University Shenzhen Hospital
2023-2025
Fudan University
2019-2024
National Health and Family Planning Commission
2019-2024
Beijing Children’s Hospital
2013-2024
Capital Medical University
2013-2024
Institute of Oceanology
2020-2024
Chinese Academy of Sciences
2020-2024
Qingdao National Laboratory for Marine Science and Technology
2020-2024
Epidemiological data on the effects of perfluoroalkyl and polyfluoroalkyl substances (PFAS) infant neurodevelopment trajectories are far from being sufficiently addressed. In this study, 1285 mother-child pairs were recruited during 2016-2017. A high-performance liquid chromatography-triple quadrupole mass spectrometer was used to measure 16 PFAS levels in cord serum. Ages Stages Questionnaires examine children's at 2, 6, 12, 24 months age. Group-based trajectory models applied derive...
Importance Although certain air pollutants have been associated with adverse obstetric outcomes, evidence regarding the association of ozone (O 3 ) exposure risk hypertensive disorders in pregnancy (HDP) is limited and inconsistent. Objectives To evaluate between gestational O HDP (ie, hypertension preeclampsia) risk, to explore window susceptibility for during pregnancy. Design, Setting, Participants This cohort study recruited pregnant patients from Obstetrics Gynecology Hospital Fudan...
Until now, the specific pathogenesis of silicosis is not clear. Exosomal miRNAs, as a newly discovered intercellular communication medium, play an important role in many diseases. Our previous research found that serum exosomal miR125a-5p was increased patients by miRNAs high-throughput sequencing. TRAF6, target gene miR125a-5p, which involved T-cell differentiation. Furthermore, results from animal study indicate knockdown miR-125a-5p can regulate T lymphocyte subsets and significantly...
Newborn screening (NBS) aims to detect congenital anomalies, and next-generation sequencing (NGS) has shown promise in this aspect. However, the NBS strategy for monogenic inherited diseases China remains insufficient. We developed a NeoEXOME panel comprising 601 genes that are relevant Chinese population found through extensive research on available databases. An interpretation system grade results into positive (high-risk, moderate-risk, low-risk genotypes), negative, carrier according...
Urea, a non-protein nitrogen for dairy cows, is rapidly hydrolyzed to ammonia by urease produced ureolytic bacteria in the rumen, and used as rumen bacterial growth. However, there limited knowledge with regard community rumen. To explore ruminal community, urea, or acetohydroxamic acid (AHA, an inhibitor of urea hydrolysis) were supplemented into simulation systems. The 16S rRNA genes sequenced Miseq high-throughput sequencing reveal ureoltyic comparing different treatments. results...
Abstract Background Stearoyl-CoA desaturase-1 (SCD1) is reported to play essential roles in cancer stemness among several cancers. Our previous research revealed significant overexpression of SCD1 primary gastric stem cells (GCSCs), with its functional role still unknown. Methods We stably established three GCSCs by sphere-forming assays and flow cytometry. Protein quantification bioinformatics analysis were performed reveal the differential protein pattern. Lentivirus-based...
This study was designed to examine the impact of prenatal fine particulate matter (PM2.5) exposure on fetal growth and underlying placental epigenetic mechanism in a cohort Chinese women. Within prospective Shanghai Mother-Child Pairs (Shanghai MCPC), 329 women carrying singleton pregnancy with due date 2018 were recruited between 2017 2018. Maternal PM2.5 levels estimated using gestational prediction model combining satellite-driven ambient concentrations personal air sampling. Fetal...
SUMMARY During the domestication and improvement processes, interspecific introgression from Gossypium hirsutum has reorganized genomic architecture of barbadense ; however, details trait‐related genetic loci remain largely unknown. Here, we perform a genome‐wide population analysis genetically recategorize 365 G. accessions into four subgroups which is different previous categorizations. A total 315 events to , primarily contributed divergence agronomic trait variation in are identified. We...
Food security is a fundamental aspect of national welfare and livelihood, it forms critical foundation for stable development. internationalization increasingly becoming measure adopted by countries to ensure food security, establishing major international grain enterprises contributes maintaining domestic stability. This paper examines how cultivate internationally competitive, large-scale enterprises. Specifically, summarizes the competitive landscape Chinese on global stage from both...
<title>Abstract</title> Background The widespread use of proton pump inhibitors (PPIs) has generated concerns about side effects Numerous studies have suggested that PPIs may increase the risk kidney disease. In particular, it is unclear whether genotype CYP2C19 enzyme system, main metabolic pathway PPIs, modifies association between and development chronic disease (CKD) or end-stage (ESKD). Methods This was a prospective cohort study white European participants from UK Biobank. CKD ESKD...
Abstract Currently, in order for the Chinese naval forces to achieve strategic transformation and move towards deep blue sea, there is an urgent need enhance capabilities of far-sea operations. Most ships various countries use gas turbines as power source, bearings supporting transmission shafts are key components restricting their performance. This paper conducts research on tilting pad journal proposes a conversion method between oil film pressure at bearing measuring point maximum pad.
Cotton fibres are single-celled trichomes arising from the epidermal cells of seed coat and may be either long (lint) or very short (fuzz). The dominant fuzzless N1 Gossypium hirsutum is a defective allele At-subgenome homoeolog MYB25-like, but genetic components underlying recessive trait G. barbadense (Gb) unknown. We have identified five loci, including major contributing locus containing MYB25-like_Dt, associated with Gb seeds based on genotyping fuzzy near isogenic lines (NILs) an...
Pathogen infection poses a serious threat to the survival and commercial quality of cultured Paa spinosa, which provide protection as substitute for wild P. spinosa. The gut microbiota plays vital roles in host health immunity. To guidance preventing intestinal diseases artificial spinosa culture, we compared compositions using high-throughput sequencing. A total 11,526 operational taxonomic units (OTUs) were identified from 14,043 sequences each sample. Cetobacterium, PW3 Bacteroides some...