- Genetic diversity and population structure
- Plant and animal studies
- Genomics and Phylogenetic Studies
- RNA and protein synthesis mechanisms
- CRISPR and Genetic Engineering
- Plant Molecular Biology Research
- Genetic Mapping and Diversity in Plants and Animals
- RNA Research and Splicing
- RNA modifications and cancer
- Insect and Pesticide Research
- Plant Parasitism and Resistance
- Wheat and Barley Genetics and Pathology
- Soybean genetics and cultivation
- Plant biochemistry and biosynthesis
- Genetics and Plant Breeding
- GABA and Rice Research
- Plant nutrient uptake and metabolism
- Aquaculture Nutrition and Growth
- Plant Reproductive Biology
- Fungal Biology and Applications
- Plant Disease Resistance and Genetics
- Microbial Community Ecology and Physiology
- Plant and Fungal Species Descriptions
- Genomics and Rare Diseases
- Antimicrobial Peptides and Activities
Hunan Normal University
2025
Changsha Hospital for Maternal and Child Health Care
2025
East China Normal University
2009-2025
Guangzhou University
2010-2025
BGI Group (China)
2025
First Affiliated Hospital of Kunming Medical University
2025
Kunming Medical University
2025
Hohai University
2020-2024
Shandong Academy of Agricultural Sciences
2024
Changjiang Water Resources Commission
2024
Kernel size-related traits are the most direct correlating with grain yield. The genetic basis of three kernel maize, length (KL), width (KW) and thickness (KT), was investigated in an association panel a biparental population. A total 21 single nucleotide polymorphisms (SNPs) were detected to be significantly (P < 2.25 × 10-6 ) associated these under four environments. Furthermore, 50 quantitative trait loci (QTL) controlling seven environments intermated B73 Mo17 (IBM) Syn10 doubled...
Goldfish have been subjected to over 1,000 y of intensive domestication and selective breeding. In this report, we describe a high-quality goldfish genome (2n = 100), anchoring 95.75% contigs into 50 pseudochromosomes. Comparative genomics enabled us disentangle the two subgenomes that resulted from an ancient hybridization event. Resequencing 185 representative variants 16 wild crucian carp revealed origin identified genomic regions shaped by sweeps linked its domestication. Our...
Abstract Liquid–liquid phase separation (LLPS) forms biomolecular condensates or coacervates in cells. Metabolic enzymes can form phase‐separated subcellular compartments that enrich enzymes, cofactors, and substrates. Herein, we report the construction of synthetic multienzyme catalyze biosynthesis a terpene, α‐farnesene, prokaryote E. coli . RGGRGG derived from LAF‐1 was used as scaffold protein to by LLPS. Multienzyme were then formed assembling two Idi IspA through an RIAD/RIDD...
The regenerative capacity of the embryonic callus, a complex quantitative trait, is one main limiting factors for maize transformation. This trait was decomposed into five traits, namely, green callus rate (GCR), differentiating (CDR), plantlet number (CRN), rooting (CRR) and browning (CBR). To dissect genetic foundation transformation, in this study multi-locus genome-wide association studies (GWAS) traits were performed population 144 inbred lines genotyped with 43,427 SNPs. Using...
Although many pathogenic copy number variations (CNVs) are associated with neuropsychiatric diseases, few of them have been functionally characterised. Here we report multiple schizophrenia cases CNV abnormalities specific to unc-51-like kinase 4 (ULK4), a novel serine/threonine gene. Deletions spanning exons 21–34 ULK4 were present in out 3,391 patients from the International Schizophrenia Consortium, but absent 3,181 controls. removing 33 and 34 large splice variant also enriched Icelandic...
Abstract Climatic oscillations during the last few million years had well‐documented effects on distributions and genomes of temperate plants animals, but much less is known their impacts tropical subtropical species. In contrast to Europe North America, ice‐sheets did not cover most China glacial periods, cycles were dramatic. Fig trees are a predominantly group pollinated by host‐specific fig wasps. We employed partial mitochondrial CO I (918 bp) nuclear ITS 2 (462 gene sequences...
The Orchidaceae is one of the largest families in plant kingdom and orchid mycorrhizae (OM) are indispensable life cycle all orchids under natural conditions. In spite this, little known concerning mechanisms underlying orchid- mycorrhizal fungi interactions. Our previous work demonstrated that non-mycorrhizal fungus Umbelopsis nana ZH3A-3 could improve symbiotic effects Epulorhiza repens ML01 by co-cultivation with Cymbidium hybridum plantlets. Thus, we investigated C. transcript profile...
SUMMARY During the domestication and improvement processes, interspecific introgression from Gossypium hirsutum has reorganized genomic architecture of barbadense ; however, details trait‐related genetic loci remain largely unknown. Here, we perform a genome‐wide population analysis genetically recategorize 365 G. accessions into four subgroups which is different previous categorizations. A total 315 events to , primarily contributed divergence agronomic trait variation in are identified. We...
The precise spatiotemporal gene expression is orchestrated by enhancers that lack general sequence features and thus are difficult to be computationally identified. By nascent RNA sequencing combined with epigenome profiling, we detect active transcription of from the complex bread wheat genome. We find genes associated transcriptional expressed at significantly higher levels, enhancer more robust in predicting activity compared chromatin features. demonstrate sub-genome-biased could drive...
Abstract Engineering the genetic code of an organism provides basis for (i) making any safely resistant to natural viruses and (ii) preventing information flow into out genetically modified organisms while (iii) allowing biosynthesis encoded unnatural polymers 1–4 . Achieving these three goals requires reassignment multiple 64 codons nature uses encode proteins. However, synonymous codon replacement—recoding—is frequently lethal, how recoding impacts fitness remains poorly explored. Here, we...
The transfer of genes between populations is increasingly important in a world where pollinators are declining, plant and animal fragmented climate change forcing shifts distribution. distances that pollen can be transported by small insects impressive, as the extensive gene flow their own populations. We compared relative ease which introduce genetic markers into host-plant Gene via seeds an Asian fig species were evaluated using cpDNA nuclear DNA markers, between-population its pollinator...