A5080509943- Electrochemical Analysis and Applications
- Helicobacter pylori-related gastroenterology studies
- scientometrics and bibliometrics research
- Chemokine receptors and signaling
- Academic Publishing and Open Access
- Wnt/β-catenin signaling in development and cancer
- Medical Imaging and Pathology Studies
- Zebrafish Biomedical Research Applications
- Cancer-related gene regulation
- Reproductive biology and impacts on aquatic species
- Gold and Silver Nanoparticles Synthesis and Applications
- Genetic and rare skin diseases.
- Spaceflight effects on biology
- Service-Learning and Community Engagement
- Cell Adhesion Molecules Research
- Architecture and Computational Design
- Ubiquitin and proteasome pathways
- Proteoglycans and glycosaminoglycans research
- Circadian rhythm and melatonin
- Immune Cell Function and Interaction
- Workplace Health and Well-being
- Bioinformatics and Genomic Networks
- Immunotherapy and Immune Responses
- Technology and Human Factors in Education and Health
- Nursing Roles and Practices
University of Nottingham
2018-2022
Hospice UK
2022
University of Sheffield
2015-2022
Marie Curie Hospice
2022
The Nature Conservancy
2002-2003
Torbay Hospital
2002
MRC Laboratory of Molecular Biology
1999
Medical Research Council
1999
Keele University
1992-1996
St James's University Hospital
1996
<h3>Abstract</h3> <b>Abstract Objectives</b> : To relate the prevalence of infection with Helicobacter pylori in adults to their living conditions childhood indentify risk factors for infection. <b>Design</b> Prevalence study IgG antibodies H (>10 μg IgG/ml, determined by enzyme linked immunosorbent assay (ELISA)) and reported other socioeconomic childhood. <b>Setting</b> Three factories Stoke on Trent. <b>Subjects</b> 471 male volunteers aged 18 65 years. <b>Main outcome measures</b>...
Escalating costs and changing population demographics are putting pressure on primary care systems to meet ever more complex healthcare needs. Non-medical ‘advanced clinical practitioner’ (ACP) roles increasingly being introduced support service transformation. This paper reports the findings of a qualitative evaluation nursing ACP across General Practices in one region UK. Data collection involved telephone interviews with 26 participants from 3 different stakeholder groups based 9 practice...
Aims: Carbon monoxide-releasing molecules (CORMs) are being developed with the ultimate goal of safely utilizing therapeutic potential CO clinically, including applications in antimicrobial therapy. Hemes generally considered prime targets and CORMs, so we tested this hypothesis using heme-deficient bacteria, applying cellular, transcriptomic, biochemical tools. Results: CORM-3 [Ru(CO)3Cl(glycinate)] readily penetrated Escherichia coli hemA bacteria was inhibitory to these Lactococcus...
Research suggests that an early connection with nature can benefit wellbeing into adulthood. However, there is less research assessing whether adolescents from formal interventions such as forest bathing (slow mindful walks). This aimed to assess urban intervention (called ParkBathe) could improve adolescents' and wellbeing.
Abstract Drosophila Armadillo is a multifunctional protein implicated in both cell adhesion, as catenin, and signaling, part of the Wingless signal transduction pathway. We have generated viable fly stocks with alterations level available for signaling. Flies from one stock overexpress and, result, increased vein material bristles wings. other reduced cytoplasmic following overexpression intracellular domain DE-cadherin. These flies display wing-notching phenotype typical wingless mutations....
Abstract Surface‐enhanced Raman scattering (SERS) of [HVO 4 ] 2− , [HPO and [HAsO has been studied on silver sol in H 2 O O; the spectra were recorded from pH 3 to 12 with excitation at 488.0, 514.5, 568.2 647.1 nm. Considerable enhancement was observed compared conventional spectra, deuteriation have no effect band positions SER spectra.
How should academic staff engage in outreach with communities outside of the university? The need academics to answer this question has intensified UK given changing priorities job roles, shaped by increasing institutional concern for widening participation, graduate employability and research impact an era austerity high tuition fees. While university professionals, such as those have access a range networks, resources support mechanisms activity, often face series profession-specific...
The global crisis sparked collaboration between publishers and service providers to successfully address an immediate problem demonstrated the possibility for future partnerships.Encouraging experts join a reviewer pool quickly review preprint journal submissions, we were able publish COVID-19 research more quickly.The initiative confirmed little author uptake of inter-publisher transfer option.The showed wide consensus on open science practices which will ensure faster reliable findings.
Appears in: INTED2024 Proceedings Publication year: 2024Pages: 5839-5843ISBN: 978-84-09-59215-9ISSN: 2340-1079doi: 10.21125/inted.2024.1530Conference name: 18th International Technology, Education and Development ConferenceDates: 4-6 March, 2024Location: Valencia, Spain
In mice, CD9 expression on the egg is required for efficient sperm-egg fusion and no effects ovulation or male fertility are observed in null animals. Here we show that cd9b knockout zebrafish also appear to have defects. contrast fewer eggs were laid by pairs and, of laid, a lower percentage fertilised. These could not be linked primordial germ cell numbers migration as these altered mutants. The decrease rescued exchanging either partner, female, wildtype partner. However, fertilisation...
Self-management tools for people with chronic or persistent pain tend to focus on symptom reporting, treatment programmes exercise and do not address barriers work, facilitators of work ability, workplace self-management strategies. We developed the Pain at Work (PAW) toolkit, an evidence-based digital toolkit provide advice how employees can self-manage their work. In a collaborative-participatory design, 4-step Agile methodology (N = 452) was used co-create healthcare professionals,...
The Orbiter Boom Sensor System (OBSS) consists of an Inspection Assembly (IBA) with two grapple fixtures for Shuttle Remote Manipulator (SRMS) and Space Station (SSRMS) grappling, sensors (LCS LDRI) at the boom tip. With SSRMS or SRMS, OBSS will be used to survey Thermal Protection (TPS) provide a platform TPS repair if necessary. As prime contractor IBA development, MDA has performed analyses dynamics simulations ensure stability SRMS during both maneuvering EVA operations. Motion tip was...
Collective cell migration is essential for embryonic development and homeostatic processes. During zebrafish development, the posterior lateral line primordium (pLLP) navigates along embryo flank by collective migration. The chemokine receptors, Cxcr4b Cxcr7b, as well their cognate ligand, Cxcl12a, are this process. We corroborate that knockdown of cd9 tetraspanin orthologue, cd9b , results in mild pLL abnormalities. Through generation CRISPR TALEN mutants, we show cd9a function partially...