The present study aimed to investigate the phytochemical profile of leaf methanol extracts fourteen Smallanthus sonchifolius (yacon) landraces and their antioxidant, anticholinesterase antidiabetic activities that could lead finding more effective agents for treatment management Alzheimer’s disease diabetes. For this purpose, antioxidant activity was assessed using different tests: ferric reducing ability power (FRAP), 2,2-diphenyl-1-picryl hydrazyl (DPPH), nitric oxide (˙NO) superoxide...

Efficacy of oryzalin to generate novel genotypes Mentha spicata L. with superior morphology and enhanced levels essential oil via in vitro polyploidization was assessed. Micropropagated nodal segments were treated at 20, 40, 60 μM for 24 48 h. The survival rate the dropped significantly increasing concentration duration oryzalin. Further, ploidy level survived plants confirmed using flowcytometry chromosome counting. A total six polyploids (2 n = 6x 72) mixoploid obtained. highest frequency...

Existing data on COPD prevalence are limited or totally lacking in many regions of Europe. The geographic information system inverse distance weighted (IDW) interpolation technique has proved to be an effective tool spatial distribution estimation epidemiological variables, when real few and widely separated. Therefore, order represent cartographically the Europe, IDW mapping was performed. point provided by 62 studies from 19 countries (21 5 Northern European countries, 11 3 Western 14...

Background/Aims. Products of Lepidium meyenii Walp. (maca) are touted worldwide as an alimentary supplement to enhance fertility and restore hormonal balance. Enhancing properties maca on semen parameters in animals were previously reported by various authors, but we present the best our knowledge first double-blind, randomized, placebo-controlled pilot trial men. The aim this study was evaluate effects serum hormone levels healthy adult Methods. A group 20 volunteers aged 20-40 years...

Essential oils (EOs) from Indian spices like Elettaria cardamomum (L.) Maton (small green cardamom), Syzygium aromaticum Merr. & L.M. Perry (clove), Cinnamomum zeylanicum Blume (cinnamon quills), and tamala (Buch.-Ham.) T. Nees C. H. Eberm (Indian bay leaves) exhibit a broad spectrum range of biological activity including antibacterial antifungal activity. Yet, there is lack data regarding the antimicrobial their formulations. Also, link between effect individual EO with chemical composition...

Brassicas are considered the third most important source of vegetable oil globally. With escalating production Brassica varieties, there is growing demand for high-yielding genotypes. Doubled haploid (DH) techniques have become very popular in various breeding programs. Such DH can play a significant role plant by accelerating homozygous lines and increasing selection efficiency. Among these methods, isolated microspore culture stands out as effective, facilitating generation higher number...

Antioxidant phytochemicals play a key role in oxidative stress control and the prevention of related disorders, such as premature aging, degenerative diseases, diabetes, cancer. The aim this study was to investigate potential antioxidant activity phytochemical profile Senecio clivicolus Wedd., perennial shrub, belonging Asteraceae family. Despite wide interest family, specie has not been investigated yet. S. aerial parts were extracted with 96% ethanol. Then, ethanol extract fractionated by...

An ethnobotanical study was performed to collect information on the use of medicinal plants in Papantla, Veracruz, Mexico. The area has a high number endemic species, and social importance community is essential for public health conservation traditional knowledge. This identified currently used, registered knowledge, documented patterns ailments treated indigenous communities Totonacas. A total 101 belonging 51 families were described by 85 local informants. Asteraceae family with highest...

Oxidative stress is involved in different diseases, such as diabetes and neurodegenerative diseases. The genus Azorella includes about 70 species of flowering plant species; most them are commonly used food particular a tea infusion the Andean region South America folk medicine to treat various chronic glabra Wedd. aerial parts were firstly analyzed for their vitro antioxidant activity using complementary assays. In particular, radical scavenging was tested against biological neutral DPPH;...

The Amazonian rainforest is a unique ecosystem that comprises habitat for thousands of animal species. Over the last decades, ever-increasing human population has caused forest conversion to agricultural land with concomitant high biodiversity losses, mainly near number fast-growing cities in Peruvian Amazon. In this research, we evaluated insect species richness and diversity five ecosystems: natural forests, multistrata agroforests, cocoa annual cropping monoculture degraded grasslands. We...

To estimate the prevalence of hepatitis C in a population northern Spain and describe (i) risk factors associated with infection (ii) distribution genotypes.Randomized cross-sectional study.A random sample 1,170 people participated study. Sociodemographic data were obtained. Antibodies against virus (anti-HCV) (HCV) genotypes determined.Nineteen (1.6%) subjects anti-HCV positive (95% CI 1.0-2.6%). In 12 cases (63%), viraemia was present, predominant genotype 1 b (80%). Anti-HCV older than...

Five landraces of Smallanthus sonchifolius [(Poepp. and Endl.) H. Robinson], known as yacon, were investigated in total phenolic content, antioxidant activity chemical composition ethanol extracts (EEs) decoction (DEs). The results demonstrated that DEs are rich acids caffeic acid, while the EEs show an higher amount flavonoids, luteolin 3′,7-O-diglucoside 7-O-glucoside. These flavonoid glycosides identified for first time yacon extracts, together with apigenin luteolin. phytochemical...

Yacon [Smallanthus sonchifolius (Poepp. et Endl.) H. Robinson], a native plant of the Andes, belongs to family Compositae (Asteraceae). It represents traditional crop from original population Peru. Most tuberous root biomass is constituted by water (> 70% fresh weight). Saccharides, especially oligofructans, form 70-80% their dry weight. Four yacon ecotypes originating Bolivia, Ecuador, Germany and New Zealand were cultivated on trial fields Czech University Agriculture in Prague 1995, 1996,...

Stilbenes contained in various foods are associated with health beneficial effects. In this study six natural and one synthetic stilbene were tested for their potential to regulate the activity of lipoxygenase cyclooxygenase vitro. The most potent inhibitor 5-lipoxygenase was pterostilbene (IC50 = 9.32 μM), whereas strongest cyclooxygenase-1 cyclooxygenase-2 pinostilbene (IC50s 1.90 0.35 μM, respectively). Pterostilbene 11.70 27.04 μM cyclooxygenase-2, respectively) oxyresveratrol 18.49;...

Abstract Essential oil from Thymus vulgaris L. has valuable therapeutic potential that is highly desired in pharmaceutical, food, and cosmetic industries. Considering these advantages the rising market demand, induced polyploids were obtained using oryzalin to enhance essential yield. However, their values unexplored. So, this study aims assess phytochemical content, antimicrobial, antioxidant, anti-inflammatory activities of tetraploid diploid thyme oils. Induced tetraploids had 41.11%...

Diabetes mellitus (DM) is a metabolic disorder characterized by the deficiency of insulin production and one concerning health problems worldwide, especially in developing countries. Considering systemic toxicity associated with current antidiabetic medications their limited efficacy, there an urgent need to discover new plant-based natural antidiabetics. Since time immemorial, medicinal plants have played important role management disorders. In recent years, herbal medicine has experienced...

Staphylococcus aureus infections present a significant threat to the global healthcare system. The increasing resistance existing antibiotics and their limited efficacy underscores urgent need identify new antibacterial agents with low toxicity effectively combat various S. infections. Hence, in this study, we have screened T-muurolol for possible interactions several aureus-specific bacterial proteins establish its potential as an alternative agent. Based on binding affinity amino acids,...