Background: Low back pain (LBP) due to lumbar spinal stenosis presents a significant clinical challenge. Epidural steroid injections (ESIs) are common treatment option; however, the optimal injection route remains debated. Objectives: To compare outcomes of parasagittal interlaminar (PIL) versus midline (MIL) ESI in patients with LBP attributed stenosis. Methods: This prospective, randomized study included and Participants were randomly assigned receive via either PIL or MIL route. Clinical...

Background: Melatonin, a hormone known for regulating sleep, may also play role in managing stress responses during anesthesia. Research suggests that it can reduce the required doses of anesthetics and minimize complications. This is particularly important patients with μ-opioid receptor addiction, who typically need higher are at increased risk cardiovascular Therefore, finding ways to lessen these complications this population crucial. Objectives: study aims investigate effects melatonin...

Background: Skin metastases occur in 5% - 30% of breast cancer patients, highlighting the need for effective treatments. Electrochemotherapy, which combines electric pulses with chemotherapy, enhances drug uptake but requires sedation due to muscle spasms caused by pulses. Dexmedetomidine, minimizes respiratory depression, and propofol, provides rapid sedation, are commonly used. However, research on their use specifically during electrochemotherapy is limited. Objectives: The aim this study...

Warfarin ought to be utilized for an extended duration in individuals with a predisposition thromboembolism, such as those atrial fibrillation or aortic valve replacement. While the primary complication of long-term warfarin usage is potential bleeding, there are also infrequent complications like vascular and tracheal calcification. We present case patient who experienced diffuse calcification result usage. A 74-year-old female patient, had been receiving chronic treatment fibrillation,...

: Primary hyperhidrosis (PH) is a condition characterized by excessive sweating. treatment options include antiperspirants or anticholinergics for symptomatic relief, while axillary and palmar can be addressed with surgery. Botulinum toxin type A (BTX-A) significant option these patients. This inhibits the release of acetylcholine, preventing overactive eccrine sweat glands from causing Despite its effectiveness in treating various neurological cosmetic conditions, Botox may pose risk severe...

Background: COVID-19 was a worldwide pandemic with international health emergencies and great challenges; care personnel shortage physician burnout is potential major challenge that should be planned managed; especially in those countries high occurrence. Objectives: This study designed to assess the attitudes of 3rd-year anesthesiology residents toward an independent one month-length clinical course for patients COVID-19. Methods: A closed self-administered questionnaire developed...

Percutaneous transforaminal endoscopic discectomy (PTED) has become popular over the years due to its safety and low invasiveness. This surgery can be performed with different anesthesia techniques; however, extent which surgeon patient are satisfied analgesia is debatable.This study investigated efficiency of S1 epidural block.This retrospective was conducted on 60 patients L4 - L5 lumbar disc herniation who underwent PTED under block. All had clinical symptoms associated unilateral...

Background: Trans-sphenoidal pituitary surgery is a minimally invasive procedure used for disorders. Objectives: This study aims to investigate the effects of dexmedetomidine and magnesium sulfate in improving anaesthesia conditions pain control during trans-sphenoidal surgery. Methods: prospective randomised clinical trial included 90 patients between 18 65 years age, with American Society Anaesthesiologists (ASA) physical status I II, who were undergoing elective Exclusion criteria change...

To reduce the drug side effects and facilitate emergence from anesthesia after complex spine surgery, various methods have been proposed. One of these is ESPB, which has less studied. Hence, we conducted this study to evaluate effectiveness ESPB on use anesthetic drugs in lumbar surgery.In study, 70 patients undergoing fusion surgery were Patients randomly divided into two groups: case group (n=35), bilateral was done, control (n=35). After standard protocols, maintained with isoflurane both...

Abstract Background : stereotactic frame-based brain biopsy is a minimally invasive neurosurgical procedure. Dexmedetomidine, an alpha-2 adrenergic agonist decreases heart rate, blood pressure, and stress response. Remifentanil short-acting opioid receptor agonist. In this study, we aim to compare the effects of dexmedetomidine remifentanil on sedation, hemodynamic alterations, analgesia, recovery profile patients who underwent biopsy. Method single-blind clinical trial was conducted. Forty...

Abstract Background Dexmedetomidine is an α2-adrenoceptor agonist that has good sedative effects with no cardiovascular instability or respiratory depression, and it might help facilitate endotracheal resection inhibit hemodynamic responses. This study's objective was to assess how intravenous affected response intubation in opium-addict patients. Materials Methods study a clinically randomized double-blind controlled trial. 100 patient diagnosis of supratentorial brain tumor undergoing...

<title>Abstract</title> <bold>Background</bold>: Sleep apnea is usually associated with negative outcomes and underdiagnoses. STOP-Bang Questionnaire a screening method for obstructive sleep (OSA) that recognized the diagnosis of OSA in surgical medical patients. This cross-sectional study aimed to evaluate ability test predict complications after supratentorial craniotomy. <bold>Methods</bold>: In study, 200 patients who were candidates craniotomy surgery referred Loghman Hospital from July...

Background: Post-lumbar surgery syndrome (PLSS) refers to persistent or recurrent pain following spinal with an unknown cause. It is commonly associated epidural fibrosis (EF). Some studies suggest that steroid injection (ESI) can effectively alleviate in PLSS, particularly when targeting the S1 nerve root using transforaminal (S1-TFESI). A key factor a successful block accurately visualizing first dorsal sacral foramen, and needle’s destination foramen. Although S1-TFESI often performed...

Introduction: Chordomas are very rare tumors infiltrating the central cranial base. Surgical resection of these is challenging, and long-term control difficult. The aim this study was to evaluate clinical presentation, radiological features, functional outcome after microsurgery adjuvant radiotherapy in a series patients harboring clival chordomas.

Objective: Arterial manifestations of Behcet’s disease are challenging and can lead to fatal complications. One the causes carotid aneurysm is disease. Extracranial internal artery aneurysms rare. This rare but important because it associated with a high risk neur thromboembolic events, cranial nerve damage, rupture. Method: We describe 19-year-old man history who presented gradual enlargement right neck mass shortness breath when he supine. Result: report examines challenges treating by...

Background: Esophageal spasm is a common problem after Foreign Body Ingestion (FBI) and causes difficulties for foreign bodies’ removal by endoscopic intervention. Sometimes, medication may help relieve spasms facilitate the of body. In current study, we introduce patient with esophageal due to FBI whom intravenous nitroglycerin was used treat spasm. Methods: The 48-year-old man who admitted emergency department Shohadaye Tajrish academic Hospital, Tehran, Iran following sever mid-anterior...

Achondroplasia is the result of a mutation in gene encoding type 3 receptor for fibroblast growth factor. This abnormality results malformation endochondral ossification. characterized by disproportionately short stature, lumbar lordosis, large head, midface hypoplasia, hands, and normal cognitive development. Our report about 28-year-old patient with achondroplasia who underwent surgery correction kyphosis due to spinal canal stenosis. In this present case we study management anesthesia.

Background: Brain tumour surgeries are high-risk because of their potential for postoperative fetal complications. This risk is exaggerated in the presence hypertrophic cardiomyopathy (HCM). Hypertrophic includes asymmetric left ventricular hypertrophy with mitral valve dysfunction that obstructs outflow tract. Various factors may accelerate this obstruction and lead to life-threatening consequences. obstructive (HOCM) a type HCM The most important parameters preload, afterload, contraction,...

Fanconi anaemia (FA) is a rare autosomal recessive inherited disease, which consists of bone marrow failure, skeletal deformities and multi organ nvolvement. Here, we report an emergency surgery on FA patient with mucormycosis infection paranasal sinuses. Since there are few reports about FA, no general consensus anaesthetic considerations so deal recommendations that based the pathology FA. Possible difficult air way main concern, low oxygen concentration avoidance nitrous oxide among...

Background: Current knowledge on antioxidant properties of anesthetics is inconclusive. Nevertheless, experiments different anesthesia-related drugs and techniques are growing. Objectives: The aim this prospective blinded randomized study was to assess the effect dexmedetomidine (Dex) infusion during anesthesia oxidative stress resulting from lumbar laminectomy. Methods: activity Dex compared placebo (normal saline) evaluated by measuring enzyme catalase (CAT), superoxide dismutase (SOD),...

Wolff-Parkinson-White syndrome is an electrophysiological disorder of the heart caused by pre-stimulation abnormal lateral pathway that can be asymptomatic or may accompanied palpitations shortness breath. We reported a case 66-yearold man with history Wolff-Parkinson who was transferred to operating room for simultaneous nephrectomy due RCC and abdominal aortic aneurysm. Managing anesthesia these patients challenging because they are prone life-threatening tachyarrhythmias. Observance all...

Down syndrome is the common chromosomal abnormality and involves multiple organs. So cardiac respiratory examinations management of anesthesia in patients with this are essential. Also complications intraoperatively common. Our case a 11-year-old patient who underwent atlas axis cervical subluxation surgery (C1-C2). The purpose to evaluate pay attention intubation its complications. Keywords: management; syndrome; difficultintubation.