A5025759506- Bone health and osteoporosis research
- Medical Imaging Techniques and Applications
- Advanced MRI Techniques and Applications
- Morphological variations and asymmetry
- Evolution and Paleontology Studies
- Advanced X-ray Imaging Techniques
- Forensic Anthropology and Bioarchaeology Studies
- Advanced X-ray and CT Imaging
- Energy Efficiency and Management
- Molecular Biology Techniques and Applications
- Endodontics and Root Canal Treatments
- Building Energy and Comfort Optimization
- Fecal contamination and water quality
- Advanced Neuroimaging Techniques and Applications
- Paleontology and Evolutionary Biology
- Genetic factors in colorectal cancer
- Fluoride Effects and Removal
- Rheumatoid Arthritis Research and Therapies
- Cerebrovascular and Carotid Artery Diseases
- Periodontal Regeneration and Treatments
- Sustainable Building Design and Assessment
- Bone Metabolism and Diseases
- Orthopaedic implants and arthroplasty
- Osteoarthritis Treatment and Mechanisms
- Physiological and biochemical adaptations
Kumasi Technical University
2022
University of Saskatchewan
2013-2021
Case Western Reserve University
2016
Food Safety Authority of Ireland
2004
In computed tomography (CT), there are many situations where reconstruction has to be performed with sparse-view data. CT imaging, strong streak artifacts may appear in conventionally reconstructed images due limited sampling rate that compromises image quality. Compressed sensing (CS) algorithm shown potential accurately recover from highly undersampled the past few years, total-variation-(TV-) based compressed algorithms have been proposed suppress artifact reconstruction. this paper, we...
Cortical bone is a dynamic tissue which undergoes adaptive and pathological changes throughout life. Direct longitudinal tracking of this remodeling process holds great promise for improving our understanding development, maintenance senescence. The application in vivo micro-computed tomography (micro-CT) has enabled trabecular microarchitecture with commercially available scanners generally operating the 10–20 µm voxel range absorbed doses reported between 0.5 1 Gy. Imaging cortical...
Abstract Cortical bone porosity and specifically the orientation of vascular canals is an area growing interest in biomedical research comparative/paleontological anatomy. The potential to explain microstructural adaptation great interest. However, determinants development canal remain unclear. Previous studies birds have shown higher proportions circumferential (called laminarity) flight bones than hindlimb bones, interpreted this as a sign that are feature for resistance torsional loading...
Abstract Objectives Differentiating human from nonhuman fragmented bone is often accomplished using histological methods if the observation of gross morphology proves insufficient. Linearly oriented primary and/or secondary osteonal systems, commonly referred to as osteon bands, are described a strong indicator bone, particularly occurrence multiple bands. This phenomenon has been conventionally documented two‐dimensional (2D) histology, but such analyses destructive and typically limited...
The orientation of vascular canals in cortical bone can reveal information about the growth rate and loading environment a bone. For example, birds it has been proposed that high proportion circumferential (a laminar cortex) is related to fast or torsional active flight. In this paper we present method measure three dimensional (3D) canals. Image data are obtained from micro-CT two angles measured: phi, determining how longitudinal canal is; theta, whether radial circumferential. This each...
Abstract Vascular canals in cortical bone during growth and development typically show an anisotropic pattern with falling into three main categories: circumferential, radial, longitudinal. Two major hypotheses attempt to explain the preferred orientations bone: that vascular canal orientation is optimized resist a predominant strain direction from functional loading, or it reflects requirements velocity. We use controlled experiment broiler chickens investigate effect of rate on...
Abstract Ancestors of the Antarctic icefishes (family Channichthyidae) were benthic and had no swim bladder, making it energetically expensive to rise from ocean floor. To exploit water column, benthopelagic hypothesized have evolved a skeleton with “reduced bone,” which gross anatomical data supported. Here, we tested hypothesis that changes icefish bones also occurred below level anatomy. Histology micro‐CT imaging representative craniofacial (i.e., ceratohyal, frontal, dentary, articular)...
Two probabilistic models were developed to estimate the acute and chronic exposure fluoride of exclusively formula-fed infants aged 0-4 months as a result consumption infant formula reconstituted with fluoridated tap water in Ireland. The estimates based on calculated accepted body weight standards, together reported concentrations powder measured values for content mean any single day areas served by 387 supplies was estimated be between 0.11 0.14 mg/kg depending age group (95th percentiles...
The orientation of vascular canals in cortical bone is thought to reflect the loading experienced by a during time when those were formed. This also be related growth rate bone, creating different patterns such as longitudinal, laminar, or radial. presence these would then faster slower that region cortex. Most our understanding canal comes from studies using histology: method which relies on 2D sections, and can only calculate relative plane sectioning. In this poster we present new method,...
The spatial distribution of vascular canals in cortical bone reflects the mechanical loading conditions present during formation bone. In flight bones birds, these have a laminar pattern, oriented circumferentially around medullary cavity. Evidence for this pattern and its relation to torsional has thus far come from histological studies, however exist 3D their cross sections 2D slice may vary actual morphology. We hypothesized that bats would show same high resolution imaging better reveal...
Cortical bone is a dynamic tissue which undergoes adaptive and pathological changes through life. An improved understanding of the spatio‐temporal nature these holds great promise for aiding study development, maintenance senescence. Commercial in vivo microCT scanners operate with maximal resolutions 10–20 um range producing doses 0.5–1 Gy trabecular imaging. As dose scales exponentially resolution, visualization cortical microarchitecture remains beyond reach systems. This explored...