Lu Yu

ORCID: 0000-0001-7842-9550
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About
Contact & Profiles
Research Areas
  • Functional Brain Connectivity Studies
  • Epilepsy research and treatment
  • EEG and Brain-Computer Interfaces
  • Neural dynamics and brain function
  • Pharmacological Effects and Toxicity Studies
  • Cholesterol and Lipid Metabolism
  • Drug Transport and Resistance Mechanisms
  • Genetics and Neurodevelopmental Disorders
  • Advanced Neuroimaging Techniques and Applications
  • Maternal and Perinatal Health Interventions
  • RNA and protein synthesis mechanisms
  • Cancer, Lipids, and Metabolism
  • Lipoproteins and Cardiovascular Health
  • Cancer Genomics and Diagnostics
  • Pregnancy-related medical research
  • Pharmacogenetics and Drug Metabolism
  • Bacterial Infections and Vaccines
  • Autoimmune Neurological Disorders and Treatments
  • Maternal and fetal healthcare
  • Infectious Encephalopathies and Encephalitis
  • Neuroscience and Neuropharmacology Research
  • Stoma care and complications
  • Cancer-related Molecular Pathways
  • Geochemistry and Geologic Mapping
  • Lipid metabolism and biosynthesis

First Affiliated Hospital of GuangXi Medical University
2014-2025

Guangxi Medical University
2014-2025

Taizhou People's Hospital
2025

Nanjing Medical University
2025

Nantong University
2025

Sichuan University
2024

West China Hospital of Sichuan University
2024

Union Hospital
2024

Huazhong University of Science and Technology
2024

Qingdao University
2024

Anatomical deficits and resting-state functional connectivity (FC) alterations in prefrontal-thalamic-cerebellar circuit have been implicated the neurobiology of schizophrenia. However, effect structural schizophrenia on causal this remains unclear. This study was conducted to examine biased by first-episode, drug-naive patients. Structural magnetic resonance imaging (fMRI) data were obtained from 49 patients 50 healthy controls. Data analyzed voxel-based morphometry Granger causality...

10.1093/schbul/sbu126 article EN Schizophrenia Bulletin 2014-08-28

Background: Early identification of individuals at high risk for aneurysms, particularly ruptured is critical timely intervention. However, existing imaging-free prediction models have significant limitations. This study aims to develop a robust model predicting aneurysm incidence and rupture by leveraging multi-omics data, including circulating proteomics, identifying specific biomarkers. Methods: UK Biobank participants (n = 502,389; mean age: 58.0 years; 54.4% female) without history...

10.1101/2025.02.25.25322902 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2025-02-26

Pheochromocytoma is a rare catecholamine-secreting tumor that can present with severe hypertensive episodes and other symptoms due to excessive catecholamine release. Approximately 30% of pheochromocytomas are associated hereditary syndromes, including multiple endocrine neoplasia type 2A (MEN2A), an autosomal dominant disorder caused by mutations in the RET proto-oncogene. MEN2A characterized presence medullary thyroid carcinoma, pheochromocytoma, primary hyperparathyroidism. We report case...

10.2147/imcrj.s504562 article EN cc-by-nc International Medical Case Reports Journal 2025-03-01

Abstract —Familial high density lipoprotein (HDL) deficiency (FHD) is a genetic disorder characterized by severe decrease in the plasma HDL cholesterol (-C) level (less than fifth percentile). Unlike Tangier disease, FHD transmitted as an autosomal dominant trait. subjects have none of clinical manifestations disease (lymphoid tissue infiltration with cholesteryl esters and/or neurological manifestations). Plasmas from contain pre–β-migrating HDLs but are deficient α-migrating HDLs. We...

10.1161/01.atv.19.1.159 article EN Arteriosclerosis Thrombosis and Vascular Biology 1999-01-01

We aimed to develop and validate a nomogram for effective prediction of vaginal birth after cesarean (VBAC) guide future clinical application.We retrospectively analyzed data from hospitalized pregnant women who underwent trial labor (TOLAC), at the Fujian Provincial Maternity Children's Hospital, between October 2015 2017. Briefly, we included singleton women, gestational age above 37 weeks primary section, in study. then extracted their sociodemographic characteristics, randomly divided...

10.1186/s12884-020-03233-y article EN cc-by BMC Pregnancy and Childbirth 2020-09-15

The exact prevalence of mirror syndrome remains unclear, and the precise clinical features need to be disclosed. We retrospectively reviewed 85 cases foetal hydrops from a total 98,484 deliveries. Of these 16 showed syndrome, while 69 did not. incidence among all deliveries was 0.0162%, that patients with 23.2%. Maternal symptoms included anaemia (n = 15), hypertension 7), proteinuria 8), pulmonary oedema 3), cardiac failure 2) HELLP 2). Placental thickness, placental weight amniotic fluid...

10.1080/01443615.2020.1718621 article EN Journal of Obstetrics and Gynaecology 2020-05-18

The brain network alterations associated with temporal lobe epilepsy (TLE) progression are still unclear. purpose of this study was to investigate altered patterns static and dynamic functional connectivity (sFNC dFNC) in TLE different durations disease. In study, 19 patients a disease duration ≤5 years (TLE-SD), 24 >5 (TLE-LD), 21 healthy controls (HCs) underwent resting-state magnetic resonance imaging attention test. We used group independent component analysis determine the target...

10.1002/jnr.24915 article EN Journal of Neuroscience Research 2021-07-16

This observational retrospective study was conducted on patients with epilepsy (PWE) in China who had at least one dose of COVID-19 vaccine and it investigated the safety vaccination by analyzing changes epileptic seizures their influencing factors. Consecutive PWE were followed up clinic between June 2021 May 2022 enrolled. Data type, demographic information, clinical characteristics epilepsy, treatment collected through a questionnaire survey retrospectively analyzed. divided into stable...

10.1080/21645515.2022.2141519 article EN cc-by-nc-nd Human Vaccines & Immunotherapeutics 2022-11-22

Abstract Objective To improve the diagnosis and treatment of anti-GABAB receptor (anti-GABABR) encephalitis prevent misdiagnosis or non-diagnosis. Methods We retrospectively examined chief clinical manifestations, auxiliary examination results, strategies, efficacy, long-term follow-up results seven consecutive patients with anti-GABABR encephalitis. Results Epileptic seizures were first symptom in 100% patients; 85.7% had memory deficit hospital, 42.8% residual symptoms cognitive impairment...

10.1007/s10072-019-04095-9 article EN cc-by Neurological Sciences 2019-10-28
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