A5046497568- Neuroinflammation and Neurodegeneration Mechanisms
- Stress Responses and Cortisol
- Phytochemicals and Antioxidant Activities
- Inflammasome and immune disorders
- Advanced Cellulose Research Studies
- Sphingolipid Metabolism and Signaling
- Autism Spectrum Disorder Research
- Medicinal Plants and Neuroprotection
- Tryptophan and brain disorders
- Bioactive natural compounds
- Biological Stains and Phytochemicals
- Nanocomposite Films for Food Packaging
- Skin Protection and Aging
- Biochemical Analysis and Sensing Techniques
- Essential Oils and Antimicrobial Activity
- Microplastics and Plastic Pollution
- Neonatal and fetal brain pathology
University of Coimbra
2019-2023
Eucalyptus globulus is planted extensively for pulp, paper and wood production. Although bioactive compounds obtained from its biomass are used as cosmetics ingredients, the skin effects were not yet fully explored. In order to fill this gap, work aimed study protective effect against damage provided by essential oil (EO) hydrodistillation of leaves, an extract residual water (HRW). The major compound identified in EO was 1,8-Cineole, phenolic acids HRW included gallic acid main constituent....
Autism Spectrum Disorders (ASDs) are a group of neurodevelopmental pathologies whose current treatment is neither curative nor effective. Anthocyanins naturally occurring compounds abundant in blueberries and other red fruits which have been shown to be successful the several neurological diseases, at least vitro vivo disease models. The aim present work was study ability an anthocyanin-rich extract (ARE) obtained from Portuguese alleviate autism-like symptoms valproic acid (VPA) mouse model...
Bacterial nanocellulose (BNC) membranes, with remarkable physical and mechanical properties, emerged as a versatile biopolymeric carrier of bioactive compounds for skin care applications. In this study, BNC membranes were loaded glycerol (as plasticizer humectant agent) different doses (1-3 μg cm-2) an aqueous extract obtained from the hydro-distillation Eucalyptus globulus Labill. leaves (HDE), application sheet facial masks. All are resistant highly malleable at dry wet states, similar or...
Diabetes during pregnancy has been shown to affect the central nervous system (CNS) of offspring, resulting in short- and long-term adverse effects. Children diabetic mothers are more likely develop cognitive impairment, also having increased susceptibility psychiatric disorders. Microglia, immune cells CNS, work as sensors environmental changes, namely metabolic challenges, early intrauterine period. During this period, microglia is actively involved processes neurogenesis, synaptic pruning...
The involvement of immunity in psychiatric disorders, such as anxiety, is typified by the morphologic adaptation microglia, immune cells brain, to anxiogenic stimuli. We previously reported sexually differentiated microglia morphology adult rodents, brain locations implicated including pre-frontal cortex. These physiologic differences likely drive sex-dependent patterns remodeling response varied stress conditions different periods life, that correlate with behavioral time-window appearance...
Ethnopharmacological relevanceSkin aging results from senescent cells accumulation, matrix metalloproteinases (MMPs) overproduction, and collagen elastin degradation, which in turn trigger skin pigmentation, dryness, wrinkles formation. In addition, the so-called inflammaging plays a role both several pathologies of skin. One most common invasive plants agroforest industrial forest plantations is Acacia dealbata, studies have been performed on pharmacological properties species due to their...