- Liver Disease Diagnosis and Treatment
- Metastasis and carcinoma case studies
- Sarcoma Diagnosis and Treatment
- Biliary and Gastrointestinal Fistulas
- Cutaneous Melanoma Detection and Management
- Pancreatitis Pathology and Treatment
- Gastric Cancer Management and Outcomes
- Parasites and Host Interactions
- Liver Diseases and Immunity
- Pneumocystis jirovecii pneumonia detection and treatment
- Helicobacter pylori-related gastroenterology studies
- Gastrointestinal Tumor Research and Treatment
- Renal and related cancers
- Renal cell carcinoma treatment
- Salivary Gland Tumors Diagnosis and Treatment
- Vascular Tumors and Angiosarcomas
- T-cell and Retrovirus Studies
- Toxin Mechanisms and Immunotoxins
- Gallbladder and Bile Duct Disorders
- Reconstructive Facial Surgery Techniques
- Vascular Malformations and Hemangiomas
- Genetic and Kidney Cyst Diseases
- Esophageal Cancer Research and Treatment
- HIV/AIDS oral health manifestations
- Tracheal and airway disorders
Hospital de Clínicas "José de San Martín"
1990-2023
University of Buenos Aires
1984-2023
Centro de Educación Médica e Investigaciones Clínicas Norberto Quirno
2011-2019
Hospital Británico de Buenos Aires
1984
Abstract Background & Aims Hepatocyte apoptosis, the hallmark of non‐alcoholic steatohepatitis ( NASH ) contributes to liver injury and fibrosis. Although, both intrinsic extrinsic apoptotic pathways are involved in pathogenesis , final common step apoptosis is executed by a family cysteine‐proteases termed caspases. Thus, our aim was ascertain if administration Emricasan, pan‐caspase inhibitor, ameliorates fibrosis murine model . Methods C57/ BL 6J‐mice were fed regular chow or high fat...
Summary Background Ursodeoxycholic acid (UDCA) is the first‐line therapy for primary biliary cholangitis (PBC). However, nearly 40% of patients have an incomplete response to UDCA. The addition bezafibrate has shown biochemical benefit in this group patients. Aim To evaluate long‐term effects UDCA combination with on histological outcomes UDCA‐refractory PBC. Methods Fifty‐nine refractory were included. Clinical parameters monitored and paired liver biopsy (PLB) was performed after 5 years...
To investigate infiltrating cells in the liver of children with type 1 autoimmune hepatitis (AH-1).
A unique case of pulmonary rhabdomyosarcoma with an isolated, symptomatic small bowel metastasis is presented. The tumor affected the middle lobe, and was treated a right pneumonectomy. Eleven months after operation, isolated metastasis, which produced intestinal obstruction, resected. patient currently alive, 11 operation. myogenous nature confirmed by immunohistochemical demonstration myoglobin in enteric lesion ultrastructural findings poorly developed sarcomeres.
Strongyloides (S.) stercoralis and hman T lymphotropic virus 1 (HTLV-1) share some endemic regions particularly in South America are mostly diagnosed elsewhere immigrants from areas such as Peru. This co-infection has not been documented Argentina although both pathogens the Northwest. We present a case of S. stercoralis. HTLV-1 with an atypical initial presentation due to gastrointestinal symptoms which presented neither eosinophilia nor presence larvae stool samples non-endemic area for...
Intrahepatic cholestasis as a paraneoplastic manifestation was first described by Dr. Maurice H. Stauffer in 1961. This primarily associated with renal cell carcinoma characterized abnormal liver enzymes without hepatic metastasis. syndrome is classified into 2 types: classical and jaundice variants. Indeed, the variant extremely rare only 13 published cases. We report case of intrahepatic type 1 papillary complete resolution after surgical treatment.
Background: Soft-tissue sarcomas (STS) are rare mesenchymal tumors with several histologic subtypes and different clinical patterns. Objective: The aim of this study was to describe the pathological characteristics surgical outcomes a series patients STS. Material methods: records 2403 undergoing surgery between October 2014 April 2018 were retrospectively reviewed. Twenty-two (0.91%) presented Results: Mean age 52 years (range: 19-92) 13 (59%) women. located in lower extremities 12 cases,...
Background: Head and neck melanomas (HNMs) have been associated with prognostic factors different from those on other locations. Objective: The goal of the present study was to compare demographic clinical characteristics outcomes surgical treatment between patients HNM trunk extremity melanoma (TEM). Material methods: records undergoing surgery for October 2014 April 2018 were retrospectively reviewed. Fifteen (22.3%) had 52 (77.7) presented TEM. Results: There no differences in age both...