A5063882493- Celiac Disease Research and Management
- Liver Disease Diagnosis and Treatment
- Microscopic Colitis
- Liver Diseases and Immunity
- Galectins and Cancer Biology
- Diabetes and associated disorders
- Systemic Lupus Erythematosus Research
- Pancreatitis Pathology and Treatment
- Immune Cell Function and Interaction
- Microbial Metabolites in Food Biotechnology
- Growth Hormone and Insulin-like Growth Factors
- Adipokines, Inflammation, and Metabolic Diseases
- Fatty Acid Research and Health
- Liver Disease and Transplantation
- Digestive system and related health
- Estrogen and related hormone effects
- Hypothalamic control of reproductive hormones
- Lipid metabolism and disorders
- Cholesterol and Lipid Metabolism
- Histone Deacetylase Inhibitors Research
- Mosquito-borne diseases and control
- T-cell and B-cell Immunology
- Intestinal and Peritoneal Adhesions
- Food composition and properties
- Peroxisome Proliferator-Activated Receptors
Consejo Nacional de Investigaciones Científicas y Técnicas
2017-2023
University of Buenos Aires
2007-2021
Hospital de Clínicas "José de San Martín"
2006-2021
Institute of Astronomy and Space Physics
2013-2015
Medical University of Graz
2013
Universidad del Rosario
2010
Renji Hospital
2010
Corporación para Investigaciones Biológicas
2010
Fundación Valle del Lili
2010
Oklahoma Medical Research Foundation
2010
Background/Aims: The aim of this exploratory trial was to establish if the probiotic Bifidobacterium natren life start (NLS) strain may affect clinical course and pathophysiological features patients with untreated celiac disease (CD). Positive findings would be helpful in directing future studies. Methods: Twenty-two adult having 2 positives CD-specific tests were enrolled. Patients randomized receive capsules before meals for 3 weeks either infantis super (Lifestart 2) (2×109...
Introduction The immune system acts on different metabolic tissues that are implicated in the pathogenesis of nonalcoholic fatty liver disease (NAFLD). Leptin and linoleic acid have ability to potentially affect cells, whereas curcumin is a known natural polyphenol with antioxidant anti-inflammatory properties. Aims This study was designed evaluate pro-inflammatory pro-oxidant effects leptin cells from patients NAFLD corroborate modulatory its preventive properties against progression using...
Obesity is associated with metabolic perturbations including liver and adipose tissue inflammation, insulin resistance, type 2 diabetes. Omega-6 fatty acids (ω6) promote omega-3 (ω3) reduce inflammation as they can be metabolized to pro- anti-inflammatory eicosanoids, respectively. 12/15-lipoxygenase (12/15-LO) enzymatically produces some of these metabolites induced by high fat (HF) diet. We investigated the effects altering dietary ω6/ω3 ratio 12/15-LO deficiency on HF diet-induced...
OBJECTIVE:Refractory sprue is a rare and severe malabsorptive disorder that mimics celiac disease but refractory to gluten-free diet without initial evidence of overt lymphoma.Treatment largely empiric often ineffective, with steroids immunosuppression being the mainstream therapeutic options.The aim this study was evaluate prospectively effect azathioprine on group patients diagnosed sprue. METHODS:We studied seven consecutive (five women two men) well-defined diagnosis lack response oral...
Toll-like receptors (TLRs) modulate T cell responses in diverse diseases. Co-stimulation of activation via TLR9 induces production interferon gamma (IFN-γ), priming which is critical for differentiation pro-inflammatory macrophages. These macrophages have a crucial role nonalcoholic fatty liver disease (NAFLD). We aimed to evaluate the expression protein on cells and consequences TLR9-mediated triggering these patients with NAFLD.Our study included 34 simple steatosis, steatohepatitis, eight...
To investigate infiltrating cells in the liver of children with type 1 autoimmune hepatitis (AH-1).
Summary What is already known about this subject Circulating immune cells such as monocytes and T infiltrate adipose tissue in the context of obesity. Plasma leptin free fatty acid levels are usually elevated Apart from involvement innate response obesity, role adaptive immunity now beginning to be unravelled. study adds committed a pro‐inflammatory state regardless their entry into obese children. Leptin linoleic effects on contribute promotion inflammation An increased Th1 cytotoxic...
Abstract During Gram-negative infections bacterial components, such as LPS and formylated peptides, exert profound physiological effects on polymorphonuclear neutrophils (PMN) resulting in increased neutrophil effector activities, including the generation of oxidative metabolites, degranulation, phagocytosis cytokine release. There is not enough evidence about relationships between peptides triggering regulation immune inflammatory response. In this study, we present indicating that...
Apoptosis of enterocytes is a feature that characterises the development lesions in coeliac disease (CD). However, intracellular pathways lead to apoptosis have not been completely clarified. Bak member Bcl-2 family proteins acts as an endogenous promoter normal enterocytes. its role has explored. We used small intestinal mucosa from patients with CD evaluate differential expression members proteins. Gene was analysed by RT-PCR biopsies 14 untreated and 19 controls without CD. In these...
Decreased dopaminergic and increased oestrogenic effects induce prolactin release DNA synthesis in secreting cells of the adult male rats. Oestrogen treatment for 7 days significantly levels prolactin, c-myc c-fos mRNAs. The effect oestrogens was reversed by administration agonist bromocriptine. There an early gradual increase mRNA beginning 30 min after injection steroid, sharply 15 oestrogen decreased to basal values later remain at this level over period time evaluated. Administration...