A5028008183- Liver Disease Diagnosis and Treatment
- Liver Diseases and Immunity
- Diabetes and associated disorders
- Hepatitis C virus research
- Pediatric Hepatobiliary Diseases and Treatments
- Liver Disease and Transplantation
- Plant Virus Research Studies
- Pancreatitis Pathology and Treatment
- Hepatitis B Virus Studies
- Viral-associated cancers and disorders
- Plant Disease Resistance and Genetics
- Liver physiology and pathology
- Hepatitis Viruses Studies and Epidemiology
- Congenital Heart Disease Studies
- Diet, Metabolism, and Disease
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Congenital Anomalies and Fetal Surgery
- Gallbladder and Bile Duct Disorders
- Renal and Vascular Pathologies
- Systemic Lupus Erythematosus Research
- Intestinal Malrotation and Obstruction Disorders
- HIV/AIDS drug development and treatment
Hospital General de Niños Ricardo Gutierrez
2008-2023
University of Buenos Aires
2012-2021
Consorci Institut D'Investigacions Biomediques August Pi I Sunyer
2011
Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas
2011
The University of Texas Health Science Center at San Antonio
2011
Abstract The immune response is critical in NAFLD pathogenesis, but the liver infiltrate’s composition and role of each T cell population still up for debate. To characterize pathogenesis pediatric adult cases, frequency localization populations [Cytotoxic Lymphocytes (CD8+), helper (CD4+), Regulatory lymphocytes (Foxp3+) Th17 (IL-17A+)] were evaluated. In portal/periportal (P/P) tracts, both age groups displayed a similar proportion CD8+ CD4+ lymphocytes. However, comparable Foxp3+ IL-17A+...
INTRODUCTION: Neonatal cholestasis due to endocrine diseases is infrequent and poorly reco-gnized. Referral the pediatric endocrinologist delayed. OBJECTIVE: We characterized in infants with congenital pituitary hormone deficiencies (CPHD), its resolution after replacement therapy (HRT). SUBJECTS AND METHODS: Sixteen patients (12 males) were included; eleven CPHD, five isolated central hypocortisolism. RESULTS: Onset of occurred at a median age 18 days life (range 2-120). Ten nine had...
Background Liver biopsy represents the gold standard for evaluating damage and progression in patients with chronic hepatitis C (CHC); however, developing noninvasive tests that can predict liver injury a growing medical need. Considering hepatocyte apoptosis plays role CHC pathogenesis; aim of our study was to evaluate presence different markers correlate cohort pediatric adult CHC. Methods biopsies concomitant serum samples from 22 were analyzed. Histological parameters evaluated. In...
The sequence variability of the Epstein-Barr virus has been extensively studied throughout previous years in isolates from various geographic regions and consequent variations at both genetic genomic levels have described. However, South America were underrepresented these studies. Here, we sequenced 15 complete EBV genomes that analyzed together with publicly available raw NGS data for 199 other parts globe by means a custom-built bioinformatic pipeline. phylogenetic relations genomes,...
Abstract Epstein Barr virus sequence variability has been deeply studied throughout the past years in isolates from various geographic regions and consequent variation at both genetic genomic levels described. However, South America have underrepresented these studies. Here, we sequenced 15 complete EBV genomes that analyzed, by means of a custom-built bioinformatic pipeline, together with publicly available raw NGS data for 199 other parts globe. Phylogenetic relations genomes, structure...
Congenital Portosystemic Shunts (CPSS) are rare vascular malformations that involve communication between the portal and systemic venous system. Patients with this condition may be asymptomatic or present severe complications such as hepatic encephalopathy (HE), hepatopulmonary syndrome (HPS), pulmonary arterial hypertension (PAH), liver nodules (LN). This study aimed to share our experience in diagnosis treatment of patients CPSS. is an observational, retrospective including diagnosed CPSS...
Introduction: Autoimmune hepatitis(AIH)in children is a progressive, severe liver disease that may be life threatening. Immunosuppression improve function and quality of life. We report 22 year follow up data in 18 pediatric patients with AIH type 2. Methods: From 1980 to 2002we followed 163 AIH:type1:138(84.6%), type2:18(11%)and 7(4.3%) autoantibodies −v e. In 2, 78 % were girls. Median ages: 6 yr mo (R:23 mo-16 yr-7 mo) Follow up: median 1yr9mo(R:2mo-15yr9mo). Autoantibodies determined by...
La derivación biliar parcial externa en pacientes con colestasis intrahepática familiar progresiva y síndrome de Alagille reduce los niveles sanguíneos sales biliares modificando su circulación enterohepática. Si esta cirugía es realizada antes la instalación cirrosis, podría mejorar sintomatología modificar progresión fibrosis hepática y, ello, evolución enfermedad, evitando o retrasando necesidad trasplante hepático. Presentamos casos ocho a quienes se les realizó una externa: cinco...