- Pediatric Pain Management Techniques
- Anesthesia and Sedative Agents
- Anesthesia and Neurotoxicity Research
- Intensive Care Unit Cognitive Disorders
- Tracheal and airway disorders
- Cardiac, Anesthesia and Surgical Outcomes
- Family and Patient Care in Intensive Care Units
- Anesthesia and Pain Management
- Airway Management and Intubation Techniques
- Respiratory Support and Mechanisms
- Neonatal Respiratory Health Research
- Congenital Diaphragmatic Hernia Studies
- Music Therapy and Health
- Child and Adolescent Psychosocial and Emotional Development
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Nausea and vomiting management
- Esophageal and GI Pathology
- Congenital Heart Disease Studies
- Infant Development and Preterm Care
- Epilepsy research and treatment
- Glycogen Storage Diseases and Myoclonus
- Identity, Memory, and Therapy
- Cardiovascular and Diving-Related Complications
- Abdominal Surgery and Complications
- Peripheral Neuropathies and Disorders
Erasmus MC - Sophia Children’s Hospital
2010-2024
Erasmus University Rotterdam
2023
University of Amsterdam
2019
Erasmus MC
2014-2018
Radboud University Nijmegen
2004-2011
Radboud University Medical Center
2004-2011
Pre-operative anxiety in children is very common and associated with adverse outcomes.The aim of this study was to investigate if virtual reality exposure (VRE) as a preparation tool for elective day care surgery lower levels anxiety, pain emergence delirium compared control group receiving usual (CAU).A randomised controlled single-blind trial.A single university children's hospital the Netherlands from March 2017 October 2018.Two-hundred children, 4 12 years old, undergoing under general...
Perioperative music interventions have been shown to reduce anxiety and pain in adults. This inexpensive, easily applicable intervention could be of benefit children as well. Our objective was determine the effects on distress, anxiety, postoperative infants undergoing surgery.The Music Under Surgery In Children study designed a parallel, single-blind, randomized controlled trial with an priori formulated hypothesis. Data were collected between August 2015 October 2016 single tertiary care...
Preoperative anxiety in children is highly prevalent and associated with adverse outcomes. Existing psychosocial interventions to reduce preoperative are often aimed at distraction of limited efficacy. Gradual exposure a far more effective way anxiety. Virtual reality (VR) provides unique opportunity gradually expose all aspects the operating theater.The aims our study (1) develop virtual (VRE) tool prepare psychologically for surgery; (2) examine efficacy VRE randomized controlled trial...
The long-term neurodevelopment of children born with oesophageal atresia (OA) is unclear. Therefore, we assessed the neurocognitive domains and their predictors. Patients OA between February 2006 December 2014, who were routinely seen at eight years as part a structured prospective longitudinal follow-up program, included. Main outcome measures need for school support, performance in various potential predictors problems. We analysed data 65 mean (SD) age 8.1 (0.2) years, whom 89% type C....
Background: Sugammadex reverses rocuronium-induced neuromuscular block (NMB). In all published studies investigating sugammadex, the primary outcome parameter was a train-of-four (TOF) ratio of 0.9. The recovery time T1 not described. This retrospective investigation describes vs. TOF after reversal NMB with sugammadex. Methods: Two were analyzed. study A, phase II dose-finding study, ASA I–II patients received an intravenous (IV) dose rocuronium 1.2 mg/kg, followed by IV sugammadex (2.0,...
Objective Approximately 50% of adolescents who have undergone scoliosis surgery still experience severe pain one year postoperatively. We explored the postoperative trajectory and potential value preoperative Thermal Quantitative Sensory Testing (T-QST) as predictor chronic postsurgical after surgery. Design Single-center prospective cohort study in undergoing Outcomes Prevalence (CPSP) course during this year. The need for rescue medication relationship between pre-operative T-QST, acute...
Intravenous opioid therapy is frequently used for postoperative pain management in children after orthopedic surgery but causes side effects such as respiratory depression, vomiting, sedation, and urinary retention. To investigate whether a continuous incisional fascia iliaca compartment (FIC) block provides more effective relief with fewer than IV morphine, we performed prospective, double-blind, randomized study to compare both techniques.Thirty (ASA physical status I-II) aged 3 mo 6 yr...
Accurate measurement of preoperative anxiety is important for pediatric surgical patients' care as well monitoring anxiety-reducing interventions. The modified Yale Preoperative Anxiety Scale-short form validated this purpose in children aged 2 years and above, but not younger children.We aimed to validate the Dutch version measuring less than old.Two investigators independently assessed infants' at holding area during induction anesthesia with COMFORT-Behavior scale-live from video...
Abstract In children, intense levels of anxiety during anesthetic induction are associated with a higher risk pain, poor recovery, and emergence delirium. Therefore, it is important to identify these high-risk children at hospital arrival. The current study examined internalizing behavior (Child Behavior Checklist, CBCL) state measures (modified Yale Preoperative Anxiety Scale, mYPAS, State Trait Inventory for Children, STAIC) arrival as predictors anesthesia. One hundred (aged 4 12 years)...
Postoperatively, young infants are admitted overnight in view of the risk for respiratory complications such as desaturation and apnea. This seems much lower than previously reported. Until what age this persists, which might actually qualify day-care treatment, is unknown.We retrospectively reviewed medical charts from preterm <45 weeks postconceptional (PCA), 45-60 PCA, term <3 months after inguinal hernia repair, January 2011 to December 2015 a large tertiary children's hospital....
Introduction Tracheomalacia (TM) often occurs in children with oesophageal atresia (OA), leading to recurrent respiratory symptoms and severe cases blue spells or ultimately arrest. In some patients, a secondary posterior tracheopexy may then be indicated. This surgery, as well morbidity, prevented by performing primary (PPT) concurrent OA correction. The aim of this trial is determine if PPT can decrease—or prevent—tracheal collapse newborns TM. Additionally, the aims whether potential...
Abstract Background Arterial blood gas analysis is the gold standard for monitoring of P a CO 2 and PaO during mechanical ventilation. However, continuous measurements would be preferred. Transcutaneous sensors continuously measure gases diffusing from locally heated skin. These have been validated in children mostly intensive care settings. Accuracy general anesthesia largely unknown. Aims We conducted study undergoing to validate use determine accuracy transcutaneous partial pressures PCO...
Summary Background Pompe disease is a rare metabolic disorder caused by deficiency of the lysosomal enzyme acid α‐glucosidase. Glycogen accumulation damages skeletal, cardiac, and smooth muscles, causing progressive debilitating muscle weakness cardiomyopathy. As life expectancy has much improved since introduction replacement therapy an increasing number patients are referred for surgical procedures. Due to potential cardiopulmonary complications, these form high‐risk group...
Background Epidural analgesia (EDA) is used as postoperative pain treatment in children, but little known about its efficacy after laparotomy children. This retrospective study investigated the of EDA children and frequencies adverse effects complications. Materials Methods Data all aged 0 to 18 years undergoing treated with our hospital from January 2014 December 2015 were collected. was classified successful either if catheter removed when there no further need, patient comfortable...
Summary We report on a case where craniosynostosis surgery for left‐sided coronal synostosis was performed successfully an 11‐month old infant with hypoplastic left ventricle dysplastic mitral valve, double outlet right ventricle, transposition of the great arteries, atrial septal defect, multiple ventricular defects, and surgically applied pulmonary banding. Craniosynostosis is considered high‐risk surgery, because possible sudden extensive blood loss, usually in cardiopulmonary healthy...
Staals, L.; Snoeck, M MJ.; Flockton, E.; Heeringa, M.; Driessen, J J. Author Information