- Reproductive Biology and Fertility
- Ovarian function and disorders
- Sperm and Testicular Function
- Endometriosis Research and Treatment
- Reproductive Health and Technologies
- Cardiac, Anesthesia and Surgical Outcomes
- Assisted Reproductive Technology and Twin Pregnancy
- Gynecological conditions and treatments
- Sexual function and dysfunction studies
- Thyroid and Parathyroid Surgery
- Reproductive System and Pregnancy
- Thyroid Cancer Diagnosis and Treatment
- Uterine Myomas and Treatments
- Sexual Differentiation and Disorders
- Biochemical Acid Research Studies
- Ectopic Pregnancy Diagnosis and Management
- Urologic and reproductive health conditions
- Pregnancy and preeclampsia studies
- Testicular diseases and treatments
- Pituitary Gland Disorders and Treatments
- Pain Management and Opioid Use
- Airway Management and Intubation Techniques
- Pelvic floor disorders treatments
- Cardiac Imaging and Diagnostics
- COVID-19 Impact on Reproduction
Ospedale Sandro Pertini
2016-2025
University of Pisa
2000-2024
ASL Roma
2020-2021
Azienda Ospedaliera Universitaria Pisana
2016-2021
Sapienza University of Rome
1997-2019
Ospedale Santa Maria Goretti
2007-2015
Casa Sollievo della Sofferenza
2012-2014
Istituti di Ricovero e Cura a Carattere Scientifico
2012-2014
Clinica Valle Giulia
2012
Centro Medicina della Riproduzione
2012
Abstract Background The beginning of 2020 was characterized by the COVID-19 pandemic. world governments have adopted restrictive measures to reduce spread infection. These could affect sexual function and quality life women living with their partner. Aim aim is assess impact social distancing caused pandemic on noninfected reproductive-age women, Methods Observational analysis sexually active partner, without infection performed. population previously answered FSFI, FSDS, SF-36...
A great deal of attention has recently been given to the essential role polyunsaturated fatty acids (PUFA) sperm membranes. We studied acid composition immature germ cells (IGC) and populations separated by Percoll gradient in ejaculate normozoospermic patients. Fatty pattern was analysed combined gas chromatography–mass spectrometry on a capillary column. In IGC, differences were found compared with mature spermatozoa, higher percentage saturated acids. On contrary, long-chain PUFA...
Short-stay thyroid surgery (<24 h hospital stay) is becoming increasingly popular but some potentially lethal complications are considered strong arguments against shortening hospitalization after thyroidectomy. The authors reviewed the data of 1,571 patients undergoing one-day over a 3-year period to determine safety and patient satisfaction. There were 1,244 females 327 males. Mean age was 43 years. Patient satisfaction evaluated by questionnaire given on discharge, while post-discharge...
Evaluation of the optimal number embryos, their quality, and precise timing for transfer are critical determinants in reproductive success, although still remaining one main challenges assisted reproduction technologies (ART). Indeed, success vitro fertilization (IVF) treatments relies on a multitude events factors involving both endometrium embryo. Despite concerted efforts fronts, overall rates IVF techniques continue to range between 25% 30%. The role implantation has been recently...
Summary Previous reports showed altered fatty acid content in subjects with sperm parameters compared to normozoospermic individuals. However, these studies focused on a limited number of acids, included short and results varied widely. We conducted case–control study involving 155 patients allocated into four groups, including normozoospermia ( n = 33), oligoasthenoteratozoospermia 32), asthenozoospermia 25), varicocoele 44). Fatty profiling, 30 species, was analyzed by validated gas...
Aim of this pilot study is to examine the effects myo-inositol administration on ovarian response and oocytes embryos quality in non PolyCystic Ovary Syndrome (PCOS) patients undergoing multiple follicular stimulation vitro insemination by conventional fertilization or intracytoplasmic sperm injection.One hundred non-PCOS women aged <40 years with basal FSH <10 mUI/ml were down-regulated triptorelin acetate from mid-luteal phase for 2 weeks, before starting protocol recovery. All received...
The advent of modern treatments together with the improvement surgical techniques has significantly increased 5-year survival rates young patients cancer. Although deleterious effects chemotherapy and radiation are well documented, controversies exist about effect cancer itself on semen parameters before treatment. We collected data 236 representative different types cancers reoffered at our institution for sperm cryopreservation aim to correlate pre-freeze type cancer, disease stage quality...
Polycystic ovary syndrome (PCOS) is the most common female endocrine disorder, and it has two main pathological aspects: reproductive metabolic. Overweight/obesity a risk factor in terms of adverse effects during hormone stimulation, reduced response to ovulation induction regimens, success IVF, an increased obstetric complications. To resolve this vicious cycle events, weight loss lifestyle modifications are promising strategies. Among these possible approaches, consumption very-low-calorie...
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Abstract Background This randomized clinical trial was performed in a single institution to compare the results of minimally invasive video-assisted parathyroidectomy (MIVAP) conducted under regional anaesthesia (RA) or general (GA). Methods Fifty-one patients undergoing MIVAP for primary hyperparathyroidism were assigned randomly either RA (26 patients) GA (25). involved bilateral deep cervical block, and local infiltration incision site with mixture 0·25 per cent lignocaine 0·15...
Premature ejaculation is the most common male sexual disorder. The aim of study was to evaluate possible therapeutic role pelvic floor muscle rehabilitation in patients affected by lifelong premature ejaculation.We treated 40 men with ejaculation, reporting, a baseline intravaginal ejaculatory latency time (IELT) ≤ 1 min, 12-week rehabilitation.At end rehabilitation, mean IELTs were calculated effectiveness therapy. At treatment, 33 (82.5%) gained control their reflex, IELT 146.2 s (range:...
Reduction in motility and number of spermatozoa change their morphology are some the most relevant causes male infertility. Production reactive oxygen species may affect motility, DNA stability spermatozoa. This study aimed at evaluating effect combined treatment with myo-inositol, alpha-lipoic acid, folic betaine vitamins (namely, Sinopol®) on semen parameters sub-fertile men.We recruited 143 men, 26-53 years aged, no-smokers, without any testicular pathologies, a normal...
Some 30% to 80% of male sub-fertility may be associated with oxidative stress that damages spermatozoa and can decrease success in vitro fertilization (IVF) techniques. This multicenter, longitudinal, prospective study aimed investigate whether oral antioxidant supplementation improved the reproductive competence men who had low rates their previous intracytoplasmic sperm injection (ICSI) cycles without azoospermia or severe oligozoospermia any identifiable andrological disease....
Tubal and uterine cavity diseases commonly compromise female fertility. At the present time, hysteroscopy, laparoscopy with chromopertubation RX-Hysterosalpingography (RX-HSG) are widely accepted screening procedures enabling effective assessment of both tubal patency cavity. Nevertheless, consistent evidence supports reliability Hysterosalpingocontrast sonography (HyCoSy) in investigation, as a part standard infertility work-up. This prospective study was aimed at evaluating tolerability...
Cholesterol is a main lipid component of sperm cell that essential for membrane fluidity, capacitation, and acrosomal reaction. Recent data obtained in bovine showed capacitation associated to the formation oxysterols, oxidized products cholesterol. The aim this study was profile oxysterol content human semen, investigate their potential role pathophysiology. Among 12 oxysterols analyzed, 25-hydroxycholesterol (25-HC) resulted most represented normozoospermic samples, its concentration...