A5028804098- Sepsis Diagnosis and Treatment
- Statistical Methods in Epidemiology
- MicroRNA in disease regulation
- Autophagy in Disease and Therapy
- Immune Response and Inflammation
- Inflammation biomarkers and pathways
- Toxoplasma gondii Research Studies
- NF-κB Signaling Pathways
Central South University
2022-2023
Third Xiangya Hospital
2022-2023
Chronic obstructive pulmonary disease (COPD) is associated with chronic inflammation that predominantly affects the lung and peripheral airways. Previous investigation has underlined efficacy of luteolin in treatment inflammation-related symptoms. Accordingly, our study concentrates on unveiling effect COPD. Mice or A549 cells were treated cigarette smoke (CS) to establish COPD models vivo vitro. Then, serum bronchoalveolar lavage fluid mice harvested. The tissues subjected hematoxylin-eosin...
Autophagy is a regulatory mechanism that packages damaged organelles, proteins, and pathogens to form vesicles transports lysosomes for degradation, enabling the recycle of useful components. Therefore, autophagy plays an important role in biological growth regulation homeostasis. In past two decades, growing evidence has shown microRNA (miRNA) closely related autophagy. MiRNA-21 promotes or inhibits via regulating relevant pathways different downstream target genes, tumors,...
Abstract Background Prognostic models in intensive care unit (ICU) were extensively applied high-income countries, but limited lower income countries for lack of resource. A simple prognostic model easy use ICU was more attractive. The modified early warning score (MEWS), age, body mass index (BMI), red cell distribution width(RDW), neutrophil to lymphocyte ratio (NLR), lactate (lac) and osmolarity easily accessible objective indexes resource settings predict mortality patients ICU. However,...
Abstract Background Prognostic models in intensive care unit (ICU) were extensively applied high-income countries, but limited lower income countries for lack of resource. A simple prognostic model easy use ICU was more attractive. The modified early warning score (MEWS), age, body mass index (BMI), red cell distribution width(RDW), neutrophil to lymphocyte ratio (NLR), lactate (lac) and osmolarity easily accessible objective indexes resource settings predict mortality patients ICU. However,...