A5018562275- Innovations in Medical Education
- Global Health and Surgery
- Ophthalmology and Visual Health Research
- Telemedicine and Telehealth Implementation
- Cardiac, Anesthesia and Surgical Outcomes
- Mobile Health and mHealth Applications
- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Pancreatic and Hepatic Oncology Research
- Hernia repair and management
- Drug-Induced Hepatotoxicity and Protection
- Empathy and Medical Education
- Trauma Management and Diagnosis
- Pancreatitis Pathology and Treatment
- Berberine and alkaloids research
- Health and Well-being Studies
- Radiology practices and education
- Computational Drug Discovery Methods
- COVID-19 and healthcare impacts
- Surgical Simulation and Training
- Cancer Mechanisms and Therapy
- Clinical Reasoning and Diagnostic Skills
- Peptidase Inhibition and Analysis
- Thyroid and Parathyroid Surgery
- Social Media in Health Education
Shaheed Zulfiqar Ali Bhutto Institute of Science and Technology
2014-2024
Pakistan Institute of Medical Sciences
2001-2022
The ZF2001 vaccine, which contains a dimeric form of the receptor-binding domain severe acute respiratory syndrome coronavirus 2 and aluminum hydroxide as an adjuvant, was shown to be safe, with acceptable side-effect profile, immunogenic in adults phase 1 clinical trials.
Disorders of steroid synthesis are a group anomalies caused by defects in any step conversion cholesterol into hormones. The disorders characterized leading to abnormalities salt-water balance and/or sexual differentiation. Congenital lipoid adrenal hyperplasia (CLAH) is the most severe form disorder accumulation outer mitochondrial membrane due steroidogenic acute regulatory protein (StAR) deficiency. Pathogenic sequence variants gene STAR encoding StAR leads CLAH. In present study,...
To evaluate the possible association of ABCB1 single nucleotide polymorphism (SNPs) gene with tacrolimus dosages, concentration-to-dose ratios (CDR) and adverse effects in Pakistani liver transplant recipients.This observational study was conducted at Shifa International Hospital, Tameer-e-Millat University, Islamabad Basic Medical Sciences Institute, Karachi from September 2016 to July 2020. Eighty-one recipients were included. Demographics, clinical data, trough levels doses monitored....
Objective: To determine the frequency of depression, anxiety, and stress among medical students to compare between undergraduate postgraduate students. Study Design: Comparative cross-sectional study. Place Duration Study: Pak Emirates Military Hospital Rawalpindi, Public Sector Medical College, Pakistan Jul Dec 2019. Methodology: A study was carried out on 200 One hundred undergraduates from all five years 100 postgraduates/residents varying specialities were asked complete DASS...
The Covid-19 pandemics caused by SARS-CoV-19, and the inadequacy of targeted medications, compelled scientists to seek new antiviral drugs. We present our current understanding plant extracts containing polyphenols that inhibit Covid-19. Natural phytochemicals (polyphenols) derived from plants have potential establish research using and/or individual compounds in treatment prevention coronavirus. polyphenolic drugs (antivirus) capable inhibiting coronavirus protein, are vital for infection...
The Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2) pandemic has become a global challenge based on its replication within the host cells that relies non-structural proteins, protease (Mpro). Flavonoids, an important class of naturally occurring compounds with medicinal importance, are frequently available fruits and vegetables. Herein, we report in silico studies flavonoids consisting molecular docking evaluation theoretical kinetics. In this study, prepared library nine...
The underlying mechanism of fibroblast growth factor receptor 1 (FGFR1) mediated carcinogenesis is still not fully understood. For instance, FGFR1 upregulation leads to endocrine therapy resistance in breast cancer patients. current study aimed identify FGFR1-linked genes devise improved therapeutic strategies. RNA-seq and microarray expression data 1,425 patients from two independent cohorts were downloaded for the analysis. Gene Set Enrichment Analysis (GSEA) was performed differentially...
Telemedicine involves the innovative application of technology to provide remote patient healthcare services especially those relating emergency care and contagious disease spread. is less developed in low-and-middle-income countries like Pakistan there little published literature on its function efficiency. Our institution was established triage patients with COVID-19 symptoms ease load departments. To conduct an analysis first month a telemedicine/tele-triage center Pakistan. determine...
The tick-borne bacterium, Borrelia burgdorferi has been implicated in Lyme disease-a deadly infection, formerly confined to North America, but currently widespread across Europe and Asia. Despite the severity of this disease, there is still no human disease vaccine available. A reliable immunoinformatic approach urgently needed for designing a therapeutic against Gram-negative pathogen. Through research, we explored immunodominant proteins B. developed novel design with great immunological...
Background: Ki-67 is a proliferation marker that used not only to categorize patients in luminal A and B subtypes of breast cancers, but also determine the aggressiveness disease triple negative human epidermal growth factor 2 (HER2) over expressed molecular subtypes. The present study was designed evaluate role with cut off value 14% subgroups its association patient prognosis. Methods: Immunostaining performed on histopathologically confirmed sections (n = 278) assess expression Ki-67,...
Objective: We assessed the effectiveness of oral Hydroxychloroquine (HC), Azithromycin (AZ) and Oseltamivir (OS), alone or combined, among patients hospitalized with mildly symptomatic coronavirus infectious disease (COVID-19).
 Methods: Following approval National Bioethics Committee prospective registration (clinicaltrials.gov NCT04338698), a multicenter randomized clinical trial adaptive design was conducted at 10 multispecialty hospitals in Pakistan. Patients were into seven...
Objective: To evaluate effectiveness of one minute preceptor Model Teaching in Ophthalmology students MBBS, MC, Mirpur, AJK.Study Design: Cross-sectional Study.Place and Duration Study: Mohtarma Benazir Bhutto Shaheed Medical College, AJK , Pakistan, from Oct 2019- Sep 2021. Methodology: After permission RERC, sampling was done by Census method, Non-Probability convenience sampling. An orientation session about teaching held, so that can understand its methodology. The were exposed to OMP...