Novel colorimetric receptors for fluoride ion sensing containing anthraquinone as a chromogenic signaling unit and imidazo-2,2'-bithiophene binding sites are reported. Well-defined color change was observed upon addition of ions to acetonitrile solutions 2. Compounds 2a−c, deprotonated after addition, were studied metal chemosensors in the presence Zn(II), Hg(II), Cu(II) solutions, especially compound 2a which displayed marked from pink yellow-gold colors complexation.

Four imidazoanthraquinone derivatives (2a-d) were synthesized and characterized their coordination behavior against selected anions cations tested. Acetonitrile solutions of probes showed charge-transfer absorptions in the 407-465 nm range. The four emitted 533-571 interval. recognition ability 2a-d was evaluated presence F(-), Cl(-), Br(-), I(-), OCN(-), BzO(-), ClO4(-), AcO(-), HSO4(-), H2PO4(-), CN(-). Only H2PO4(-) induced a new red-shifted absorption band that attributed to...

In chronic wound (CW) scenarios, Staphylococcus aureus-induced infections are very prevalent. This leads to abnormal inflammatory processes, in which proteolytic enzymes, such as human neutrophil elastase (HNE), become highly expressed. Alanine-Alanine-Proline-Valine (AAPV) is an antimicrobial tetrapeptide capable of suppressing the HNE activity, restoring its expression standard rates. Here, we proposed incorporation peptide AAPV within innovative co-axial drug delivery system, liberation...

Chronic wounds represent a serious worldwide concern, being often associated with bacterial infections. As the prevalence of infections increase, it is crucial to search for alternatives. Essential oils (EOs) constitute promising option antibiotics due their strong anti-inflammatory, analgesic, antioxidant and antibacterial properties. However, such compounds present high volatility. To address this issue, drug delivery system composed coaxial wet-spun fibers was engineered different EOs,...

Fluorescent labelling is a versatile tool to visualize biomolecules containing primary amines in their cellular environment, allowing the study of function or interactions. Here, three organic fluorophores that can irreversibly bind amine group on target biomolecule are reported. They consist push–pull heterocyclic dyes based bithiophene and incorporating terminal N -hydroxysuccinimidyl ester as reactive for groups from (poly)amines, peptides proteins. Their potential chemosensors amines,...

The incidence of bacterial infections associated with chronic wounds (CWs) has increased in recent years.

Abstract A series of nonlinear optical chromophores 6 containing a substituted benzothiazole ring have been synthesized and characterized. 1,3‐Benzothiazoles were prepared by treating various formyl derivatives thienyl compounds with ortho ‐aminobenzenethiol in fair to excellent yields. These turn Suzuki coupling between aryl precursors. The electronic interactions donor acceptor end groups the conjugated 1,3‐benzothiazoles are revealed intense markedly solvatochromic CT transitions....

A family of heterocyclic thiosemicarbazone dyes (3a-f and 4) containing furyl groups was synthesized in good yields, characterized their response acetonitrile the presence selected anions studied. Acetonitrile solutions 3a-f 4 showed absorption bands 335-396 nm range which are modulated by electron donor or acceptor strength systems appended to moiety. Fluoride, chloride, bromide, iodide, dihydrogen phosphate, hydrogen sulphate, nitrate, acetate cyanide were used recognition studies. From...

The synthesis and comprehensive characterization of the excited states four novel triphenylamine-benzimidazole derivatives has been undertaken in solution (ethanol methylcyclohexane) at room temperature. This includes determination absorption, fluorescence, triplet-triplet absorption spectra, together with quantum yields internal conversion, intersystem crossing, singlet oxygen. From overall data radiative radiationless rate constants could be obtained, it is shown that compounds are highly...

Seven new bioinspired chemosensors (2–4 and 7–10) based on fluorescent peptides were synthesized characterized by elemental analysis, 1H 13C NMR, melting point, matrix-assisted laser desorption–ionization time-of-flight mass spectrometry (MALDI-TOF-MS), IR UV–vis absorption emission spectroscopy. The interaction with transition- post-transition-metal ions (Cu2+, Ni2+, Ag+, Zn2+, Cd2+, Hg2+, Pb2+, Fe3+) has been explored fluorescence spectroscopy MALDI-TOF-MS. reported peptide systems,...

Dipeptide biomaterials are strong piezoelectric materials that can convert applied mechanical forces into electricity. We have developed large-scale hybrid electrospun arrays containing N-tert-butoxycarbonyl (Boc) diphenylalanine in the form of nanotubes embedded biocompatible polymers. These nanofibers exhibit properties when a periodic force is applied. The nanostructured were produced by electrospinning technique. Optical absorption measurements show four bands spectral region 240-280 nm...

Novel imidazo-anthraquinones functionalised with indole and carbazole have been synthesised characterised their evaluation as colorimetric chemosensors was carried out in acetonitrile well acetonitrile/H2O (97:3) the presence of several anions such F− , Cl− Br− I− CN− AcO− BzO− . In addition, behaviour H+ OH− also studied. Upon addition to solutions compounds 1–3, a marked colour change from yellow orange observed fluorescence emission 1 2 switched 'on'. The recognition organic aqueous...

Unnatural amino acids with enhanced properties, such as increased complexing ability and luminescence, are considered to be highly attractive building blocks for bioinspired frameworks, probes biomolecule dynamics, sensitive fluorescent chemosensors, peptides molecular imaging, among others. Therefore, a novel series of emissive heterocyclic alanines bearing benzo[d]oxazolyl unit functionalized different π-spacers (aza)crown ether moieties was synthesized. The new compounds were completely...

The synthesis of new fluorescent probes containing the thiophene andbenzoxazole moieties combined with an alanine residue is described. resulting highlyfluorescent heterocyclic derivatives respond via a quenching effect, withparamagnetic Cu(II) and Ni(II) metal ions diamagnetic Hg(II), as shown by theabsorption steady-state fluorescence spectroscopy studies. formation ofmononuclear or dinuclear complexes was postulated based on presence thefree carboxylic acid binding site also interaction...