A5075265320- Salmonella and Campylobacter epidemiology
- Viral gastroenteritis research and epidemiology
- Listeria monocytogenes in Food Safety
- Bacteriophages and microbial interactions
- Food Safety and Hygiene
- Animal Nutrition and Physiology
- Vibrio bacteria research studies
- Viral Infections and Vectors
- Cancer Research and Treatments
- Advanced Chemical Sensor Technologies
- Genomics and Phylogenetic Studies
- Bacillus and Francisella bacterial research
- Bartonella species infections research
- Microbial Inactivation Methods
- Bacterial Genetics and Biotechnology
- Meat and Animal Product Quality
- Probiotics and Fermented Foods
- Escherichia coli research studies
- Plant and animal studies
- Bacterial biofilms and quorum sensing
- Rabies epidemiology and control
- Clostridium difficile and Clostridium perfringens research
- Vector-borne infectious diseases
- Yersinia bacterium, plague, ectoparasites research
- Congenital gastrointestinal and neural anomalies
Sécurité des Aliments et Microbiologie
2010-2024
Oniris
2010-2024
University of Blida
2023
Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
2020-2022
Agence Nationale de Sécurité Sanitaire de l’Alimentation, de l’Environnement et du Travail
2022
Statens Serum Institut
2022
Bipar
2004-2020
École Nationale Vétérinaire d'Alfort
2004-2020
Mycologie et Sécurité des Aliments
2016-2019
Université Nantes Angers Le Mans
2012-2016
According to the World Health Organization estimates in 2015, 600 million people fall ill every year from contaminated food and 420,000 die. Microbial risk assessment (MRA) was developed as a tool reduce prevent risks presented by pathogens and/or their toxins. MRA is organized four steps analyse information assist both designing appropriate control options implementation of regulatory decisions programs. Among steps, hazard characterisation performed establish probability severity disease...
Campylobacter jejuni is the leading cause of bacterial enteritis in Europe. Human campylobacteriosis cases are frequently associated to consumption contaminated poultry meat. To survive under environmental conditions encountered along food chain i.e. from digestive tract its natural reservoir consumer's plate, this pathogen has developed adaptation mechanisms. Among those, biofilm lifestyle been suggested as a strategy environment and atmospheric conditions. Recently, clinical isolate C. Bf...
Campylobacter jejuni is a leading cause of bacterial gastroenteritis worldwide. Infection generally occurs after ingestion contaminated poultry products, usually conserved at low temperatures. The mechanisms promoting survival C. in the cold remain poorly understood despite several investigations. present study provides insight into mechanism by establishing involvement polynucleotide phosphorylase (PNPase), 3'-5' exoribonuclease with multiple biological functions survival. role PNPase was...
Campylobacter jejuni is a leading cause of bacterial enteritis worldwide. This microaerophilic bacterium can survive in aerobic environments, suggesting it has protective mechanisms against oxidative stress. The clinical C. Bf strain characterized by an increased resistance to oxygen. study aimed characterize the behavior under atmosphere and response ROS-promoter agents. Growth was studied both microaerobic conditions using classic cultivable methods. Electronic microscopy mreB gene...
Polynucleotide phosphorylase, encoded by the pnp gene, is known to degrade mRNA, mediating post-transcriptional regulation and may affect cellular functions. The role of PNPase pleiotropic. As two major ribonucleases (RNase E RNase II) Escherichia coli are absent from Campylobacter genome, this study was focused on PNPase. effect mutation C. jejuni phenotypes proteome investigated. inactivation gene reduced significantly ability adhere invade Ht-29 cells. Moreover, mutant strain exhibited a...
Campylobacter jejuni accounts for one of the leading causes foodborne bacterial enteritis in humans. Despite being considered an obligate microaerobic microorganism, C. is regularly exposed to oxidative stress. However, its adaptive strategies survive atmospheric oxygen level during transmission humans remain unclear. Recently, atypical clinical Bf strain was shown by unexpected ability grow under ambient atmosphere. Here, we aimed understand better biological mechanisms underlying...
Transposon mutagenesis of Bacillus cereus ATCC 14579 yielded cold-sensitive mutants. Mutants genes encoding enzymes the central metabolism were affected by cold, but also other stresses, such as pH or salt, whereas a mutant with transposon insertion in promoter region BC0259 gene, putative DEAD-box RNA helicase displaying homology Escherichia coli CsdA and subtilis CshA helicases, was only cold-sensitive. Expression gene at 10 degrees C is reduced mutant. Analysis 5' untranslated revealed...
Waardenburg syndrome (WS) is a genetic disorder characterized primarily by depigmentation of the skin and hair, heterochromia irides, sensorineural deafness, sometimes dystopia canthorum, Hirschsprung disease. WS presents large clinical heterogeneity. Four different types have been individualized linked to 5 genes. We report 2 cases type II 1 case IV from Lebanon Syria. The studies revealed novel mutations in <i>MITF</i> gene homozygous mutation <i>EDNRB</i> case....
Campylobacter jejuni is a foodborne bacterial pathogen, which now considered as leading cause of human gastroenteritis. The information regarding ribonucleases in C. very scarce but there are hints that they can be instrumental virulence mechanisms. Namely, PNPase (polynucleotide phosphorylase) was shown to allow survival refrigerated conditions, facilitate swimming, cell adhesion, colonization and invasion. In several microorganisms synthesis auto-controlled an RNase III (ribonuclease...
Campylobacter jejuni has been reported as a major cause of bacterial food-borne enteritides in developed countries during the last decade. Despite its fastidious growth requirements, including low level oxygen and high CO2, this pathogen is able to persist environment without permanent loss viability virulence. As C. not multiply outside host, cells spend significant amount time stationary phase growth. The entry into often correlated resistance various stresses bacteria. switching between...
ABSTRACT In this study, we describe the draft genome sequence of a Campylobacter jejuni clinical isolate issued from French patient suffering severe campylobacteriosis. This atypical strain is characterized by an unusual resistance to oxygen and ability grow under aerobic atmosphere, characteristic as-of-yet unique species.