A5035439377- Vector-borne infectious diseases
- Bartonella species infections research
- Viral Infections and Vectors
- Rabies epidemiology and control
- Vector-Borne Animal Diseases
- Microbial infections and disease research
- Yersinia bacterium, plague, ectoparasites research
- Mosquito-borne diseases and control
- Zoonotic diseases and public health
- Toxin Mechanisms and Immunotoxins
- Animal Disease Management and Epidemiology
- Mycobacterium research and diagnosis
- Autoimmune Bullous Skin Diseases
- Insect and Pesticide Research
- Oral and gingival health research
- Streptococcal Infections and Treatments
- Immune Cell Function and Interaction
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- T-cell and B-cell Immunology
- Bacillus and Francisella bacterial research
- Genital Health and Disease
- Herpesvirus Infections and Treatments
- Virus-based gene therapy research
- Diphtheria, Corynebacterium, and Tetanus
- Veterinary Oncology Research
Bipar
2014-2024
École Nationale Vétérinaire d'Alfort
2015-2024
Agence Nationale de Sécurité Sanitaire de l’Alimentation, de l’Environnement et du Travail
2018-2024
Département Santé Animale
2018-2024
Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
2018-2024
Paris-Est Sup
2012-2018
Université Paris-Est Créteil
2012-2016
Hôpital Saint-Louis
1999
Inserm
1999
École Normale Supérieure - PSL
1997
ABSTRACT Ecological changes are recognized as an important driver behind the emergence of infectious diseases. The prevalence infection in ticks depends upon ecological factors that rarely taken into account simultaneously. Our objective was to investigate influences forest fragmentation, vegetation, adult tick hosts, and habitat on three tick-borne bacteria, Borrelia burgdorferi sensu lato, Anaplasma phagocytophilum , Rickettsia sp. spotted fever group, questing Ixodes ricinus ticks, taking...
There has been a growing interest in camel anaplasmosis due to its recent emergence this reservoir species and concerns for zoonotic potential. The epidemiology of camels therefore remains poorly understood mostly because belong marginalised poor often transhumant populations whose interests are largely neglected. Most studies have relied on microscopy serology diagnosis only three studies, undertaken Tunisia, Saudia Arabia China, used molecular diagnostics. present work characterises...
Bartonella henselae (Rhizobiales: Bartonellaceae) is a Gram-negative fastidious bacterium of veterinary and zoonotic importance. The cat flea Ctenocephalides felis (Siphonaptera: Pulicidae) the main recognized vector B. henselae, transmission among cats humans occurs mainly through infected feces. present study documents use quantitative molecular approach to follow daily kinetics within its excreted feces after exposure blood for 48 h in an artificial membrane system. DNA was detected both...
There are a few investigations into endometritis in the bitch and its relationship with failure to conceive remains unclear. This may be because of difficulty collecting uterine samples for further investigations. Recently, transcervical catheterization by vaginal endoscopy has been introduced allowing evaluation endometrium. In this study, cytology bacteriology were evaluated 26 infertile bitches. Endometritis was bacterial origin most cases (70% affected bitches), but these results...
Two strains of bacteria isolated from the blood French domestic cows were found to be similar Bartonella species on basis phenotypic characteristics. Genotypic analysis based sequence comparison 16S rRNA and citrate synthase (gltA) genes DNA-DNA hybridization showed that two isolates represent a distinct new Bartonella. Moreover, phylogenetic inferred gltA sequences demonstrated is related other ruminant-derived species. The name chomelii proposed for type strain sp. nov. A828T (=CIP...
Screening of extended-spectrum β-lactamase (ESBL)-producing Gram-negative bacteria in companion animals living the Paris area France identified a high rate CTX-M-15-producing Klebsiella pneumoniae. Those isolates were recovered during 2010-2011 period from both infections and asymptomatic colonizations. Sequence typing revealed that most these belonged to sequence type ST274. Interestingly, bla(CTX-M-15) gene was located on specific novel plasmid scaffold. These findings highlight may be...
In Escherichia coli, only one essential oligoribonuclease (Orn) can degrade oligoribonucleotides of five residues and shorter in length (nanoRNA). Bacillus subtilis, NrnA NrnB, which do not show any sequence similarity to Orn, have been identified as functional analogues Orn. Sequence comparisons did identify orn, nrnA or nrnB homologues the genomes Chlamydia/Cyanobacteria Alphaproteobacteria family members. Screening a genomic library from Bartonella birtlesii, member Alphaproteobacteria,...
Ixodid ticks are hematophagous arthropods considered to be prominent ectoparasite vectors that have a negative impact on cattle, either through direct injury or via the transmission of several pathogens. In this study, we investigated molecular infection rates numerous tick-borne pathogens in sampled cattle from Kabylia region, northeastern Algeria, using high-throughput microfluidic real-time PCR system. A total 235 belonging seven species genera Rhipicephalus, Hyalomma, and Ixodes were...
Molecular epidemiology represents a powerful approach to elucidate the complex epidemiological cycles of multi-host pathogens, such as Anaplasma phagocytophilum. A. phagocytophilum is tick-borne bacterium that affects wide range wild and domesticated animals. Here, we characterized its genetic diversity in populations French cattle; then compared observed genotypes with those found horses, dogs, roe deer determine whether are shared among different hosts. We sampled 120 animals (104 cattle,...
Bartonella spp. are small hemotropic bacteria infecting mammals. Four species have been recently described in cattle and wild ruminants. To date, the biology possible pathogenic role of isolated from ruminants poorly understood. Therefore, a dairy herd 448 cows heifers was surveyed order to establish prevalence bovis B. chomelii infections, level bacteremia, relationship between bacteremia age or pregnancy status. The putative impact infection on production performance (individual milk cell...
Bartonella are hemotropic bacteria responsible for emerging zoonoses. These heme auxotroph alphaproteobacteria must import their growth, since they cannot synthesize it. To exogenous heme, genomes encode a complete uptake system enabling transportation of this compound into the cytoplasm and degrading it to release iron. In addition, these four or five outer membrane binding proteins (Hbps). The structural genes highly homologous expressed differently depending on oxygen, temperature...
A cross-sectional study was conducted to determine the species of Anaplasma spp. and estimate its prevalence in cattle three main cattle-producing Galapagos Islands (Santa Cruz, San Cristóbal Isabela) using indirect PCR assays, genetic sequencing ELISA. Ticks were also collected from scanned for 47 tick-borne pathogens a 48 × real-time chip. mixed effects logistic regression performed identify potential risk factors explaining infection cattle. A. phagocytophilum not detected any tested...
The causative agent of tick-borne fever and human granulocytic anaplasmosis, Anaplasma phagocytophilum, is transmitted by Ixodes ricinus, currently considered an emerging disease throughout Europe. In this study, we established a model A. phagocytophilum sheep infection I. ricinus transmission using the European Norway variant 2 ovine strain (NV2Os) propagated in both IDE8 ISE6 tick cells. Two were inoculated with cells infected NV2Os. Both developed as determined qPCR PCR, presence 4 days...