A5085583612- Salmonella and Campylobacter epidemiology
- Animal Nutrition and Physiology
- Viral gastroenteritis research and epidemiology
- Listeria monocytogenes in Food Safety
- Animal Virus Infections Studies
- Clostridium difficile and Clostridium perfringens research
- Veterinary medicine and infectious diseases
- vaccines and immunoinformatics approaches
- Probiotics and Fermented Foods
- Bacteriophages and microbial interactions
- Bacterial biofilms and quorum sensing
- Chemical and Physical Properties in Aqueous Solutions
- Milk Quality and Mastitis in Dairy Cows
- Biosensors and Analytical Detection
- Ruminant Nutrition and Digestive Physiology
- Cancer Research and Treatments
- Vibrio bacteria research studies
- Agricultural safety and regulations
- Antibiotic Resistance in Bacteria
- Enterobacteriaceae and Cronobacter Research
- Protein Hydrolysis and Bioactive Peptides
- Contact Dermatitis and Allergies
- Bacterial Genetics and Biotechnology
- Advancements in Transdermal Drug Delivery
- Leptospirosis research and findings
Agence Nationale de Sécurité Sanitaire de l’Alimentation, de l’Environnement et du Travail
2014-2025
Sécurité et Qualité des Produits d'Origine Végétale
2013-2024
CEA Paris-Saclay
2022
Université Bretagne Loire
2016-2018
Université Européenne de Bretagne
2015
Université de Lorraine
2015
Laboratoire Animal et Agroécosystèmes
2015
Université de Rouen Normandie
2008-2014
Laboratoire de Biotechnologie et Chimie Marines
2008
Université de Bretagne Sud
2008
Poultry meat is the major source of human campylobacteriosis, most frequently reported zoonosis in EU. The prevalence Campylobacter colonization European broiler flocks 71%. Despite considerable efforts, there still no effective strategy available to prevent or reduce broilers. This study tested a wide variety feed additives shedding primary poultry production. Twelve containing organic fatty acids, monoglycerides, plant extracts, prebiotics, probiotics were tested. For each additive,...
Campylobacteriosis is the most prevalent bacterial foodborne gastroenteritis affecting humans in European Union. Human cases are mainly due to Campylobacter jejuni or coli , and contamination associated with handling and/or consumption of poultry meat. In fact, constitutes bacteria’s main reservoir. A promising way decreasing incidence campylobacteriosis would be decrease avian colonization. Poultry vaccination potential for this purpose. However, despite many studies, there currently no...
This report describes the work developed during execution of Review Impact MICrobiome In Assesment (RIMICIA) project. project has performed a comprehensive and critical assessment evidence-based research about: i) impact dietary compounds in human some domestic animals (i.e., poultry, ruminants pigs) gut microbiome; ii) most representative vitro vivo models microbiota currently used microbiome studies; iii) methodology to measure changes microbiota. also gathered appraised information about...
Campylobacter is the leading cause of human bacterial gastroenteritis in European Union. Birds represent main reservoir bacteria, and campylobacteriosis mainly occurs after consuming and/or handling poultry meat. Reducing avian intestinal loads should impact incidence diseases. At primary production level, several measures have been identified to reach this goal, including vaccination poultry. Despite many studies, however, no efficient vaccine currently available. We recently new candidates...
A total of 636 day-of-hatch Ross 308 broilers chicks were used in 4 independent trials carried out to screen the effect 12 feed additives on reducing cecal colonization Campylobacterin broilers. The tested probiotics based B. subtilis and S. cerevisae, a garlic extract, blend herbal substances essential oils, two different combinations oils organic acids (OA), mixtures flavoring compounds, medium chain fatty (MCFA), monoglycerides (MG) MCFA MG-MCFA+OA. At 14 days age, all birds orally...
Abstract Background Pseudomonas fluorescens is present in low number the intestinal lumen and has been proposed to play a role Crohn's disease (CD). Indeed, highly specific antigen, I2, detected CD patients correlated severity of disease. We aimed determine whether P. was able adhere human epithelial cells (IECs), induce cytotoxicity activate proinflammatory response. Results Behaviour clinical strain MFN1032 compared that psychrotrophic MF37 opportunistic pathogen aeruginosa PAO1. Both...
The effect of hyperosmotic condition on the outer membrane protein (Omp) composition Pseudomonas fluorescens was investigated by proteomic analyses. abundances 12 proteins, including porins, lipoproteins, and flagella subunit FliC, were modified. This at least partly explained altered gene expression, as shown mRNA level study. In agreement with Omp changes, resulted in vesicle formation modifications mobility antibiotic susceptibility.
Campylobacteriosis is reported to be the leading zoonosis in Europe, and poultry main reservoir of Campylobacter. Despite all efforts made, there still no efficient vaccine fight this bacterium directly poultry. Recent studies have interactions between chicken immune system gut microbiota response Campylobacter colonisation. The present study was designed analyse more depth responses caecal following vaccination with a DNA prime/protein boost flagellin-based that induces some protection...
Poultry and poultry meat are considered the most important sources of human campylobacteriosis salmonellosis. However, data about occurrence Campylobacter Salmonella concomitantly with intestinal protozoa such as Blastocystis sp. in remain very scarce. Therefore, this study aimed to investigate presence possible interactions between these three microorganisms fecal samples from 214 chickens collected either on farms or live bird markets Egypt. The results obtained showed that spp., were...
The poultry reservoir, especially broiler meat, is generally recognized as one of the most-important sources for human Campylobacteriosis. measures to control
Campylobacter infections traced mainly to poultry products are major bacterial foodborne zoonoses. Among the many control strategies evaluated at primary level reduce these infections, vaccination could be a solution, but no effective vaccines available date. A better understanding of immune mechanisms involved in protection against would helpful for designing novel vaccine strategies. The present study was designed analyze more depth responses developed broilers order potentially identify...
ABSTRACT Most animal experiments on cosmetics safety are prohibited and since March 2013, this obligation includes sensitization tests. However, until now there has been no validated alternative in vitro method. In work, 400 compounds used the cosmetic industry were selected to cover greatest diversity of structures, biological activities sensitizing potential. These molecules submitted a series tests aimed at reproducing essential steps distinguish between irritations, i.e., transcutaneous...
Campylobacter infections, traced to poultry products, are major bacterial foodborne zoonoses, and vaccination is a potential solution reduce these infections. In previous experimental trial using plasmid DNA prime/recombinant protein boost vaccine regimen, two candidates (YP437 YP9817) induced partially protective immune response against in broilers, an impact of the batch on efficacy was suspected. This new study designed evaluate different batches previously studied recombinant proteins...
Summary A randomized controlled trial ( RCT ) was carried to evaluate the effect of a feed additive on Campylobacter contamination broilers reared in commercial conditions. Twenty‐four broiler flocks naturally contaminated with were enrolled : 12 assigned control group (C) fed conventional finishing from 4 weeks age slaughter (around 35 days), and other (S) supplemented 250 ppm patented (an ion‐exchanged clay compound) previously proven reduce caeca under experimental Enumeration colonies (8...
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