A5104060093- Glioma Diagnosis and Treatment
- Obesity, Physical Activity, Diet
- Eosinophilic Esophagitis
- Metabolism and Genetic Disorders
- Boron Compounds in Chemistry
- Birth, Development, and Health
- Neurological and metabolic disorders
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Animal Genetics and Reproduction
- Drug-Induced Adverse Reactions
- Diabetes Management and Research
- Food Allergy and Anaphylaxis Research
- Mast cells and histamine
- Nausea and vomiting management
- Maternal and Neonatal Healthcare
- Fungal Infections and Studies
- Sinusitis and nasal conditions
- Electroconvulsive Therapy Studies
- Indigenous Health and Education
- Nutritional Studies and Diet
- Pesticide Exposure and Toxicity
- Liver Disease Diagnosis and Treatment
- Chemical Reactions and Isotopes
- Neurological diseases and metabolism
- Medieval Architecture and Archaeology
Administração Regional de Saúde de Lisboa e Vale do Tejo
2025
Universidade do Porto
2020-2025
Hospital de São João
2023-2024
Hospital Dr. Nélio Mendonça
2024
Centro Hospitalar de Lisboa Central
2023
Hospitais da Universidade de Coimbra
2023
Diabetes Australia
2023
Centro Hospitalar do Porto
2009-2020
Hospital Prof. Dr. Fernando Fonseca
2018
Universidade Federal de São Paulo
2018
Background Anti-calcitonin gene-related peptide (CGRP) monoclonal antibodies (mAbs) are considered a safe and well-tolerated option for migraine prophylaxis. However, caution is advised in patients with vascular comorbidities. In hereditary transthyretin amyloidosis (ATTRv amyloidosis), amyloid deposition leptomeningeal vessels has been reported, potentially leading to cerebral angiopathy. The efficacy safety of anti-CGRP this condition have not described. Methods We present three ATTRv...
To characterize a cohort of pediatric thyroid cancer patients, focusing on clinical features and outcomes stratified by age. Subjects and. This retrospective analysis included 63 differentiated patients treated at Portuguese reference hospital over period 20 years. Data extracted from records covered demographics, presentation, family history, tumor characteristics, treatment modalities, complications, disease status, survival outcomes. Patients younger than 12 years were compared to those...
Various risk factors for portal vein thrombosis (PVT) development in patients with cirrhosis have been identified, but the role of systemic inflammatory reaction is unknown. The study aims to assess association between markers inflammation and PVT cirrhosis.Between January 2014 October 2015, 107 outpatients no were recruited, followed till February 2017. White blood cell count, serum concentrations high-sensitive C-reactive protein, ferritin, tumor necrosis factor-alpha interleukin-6 (IL-6)...
The majority of acute iron toxicity cases occur in young children from accidental ingestion. In adults, poisoning is rare and mostly due to intentional Physicians, particularly those who do not routinely treat pediatric patients, are often unfamiliar with the clinical manifestation poisoning, its management, potential for multiple organ failure, especially liver damage. Severe hepatotoxicity treated transplantation very limited published literature. We report a case severe tablet overdose...
Introducao : A gravidez na adolescencia tem assumido uma expressao significativa sociedade portuguesa com prevalencia a rondar os 14%. Este facto, aliado ao recente alargamento de atendimento pediatrico para 18 anos, coloca novos desafios pediatra. Objectivos Conhecer padroes sexualidade e contracepcao adolescencia, procurando avaliar condutas sexuais risco gravidez. Metodos: Estudo transversal, desenvolvido numa Escola Secundaria Publica urbana, no qual foram englobados 177 adolescentes,...
Brazil is experiencing a nutritional transition characterized by reduction in the prevalence of deficits and an increase overweight obesity, not only adults but also children adolescents.This study was designed to evaluate factors associated with obesity Brazilian 5-year-old preschoolers.A cross-sectional cohort 232 preschoolers born Diamantina/Minas Gerais, Brazil, undertaken. The data, including socioeconomic status, anthropometry, diet, previous history family history, were collected...
Introducao: Nas ultimas decadas, a melhoria dos cuidados de saude perinatais, refletiu-se numa significativa diminuicao da mortalidade associada prematuridade. No entanto, esta nao se acompanhou forma proporcional reducao morbilidade, particularmente nivel do neurodesenvolvimento. Objectivos: Avaliar o desenvolvimento psicomotor (DPM) grandes prematuros, identificar perturbacoes neurodesenvolvimento, analisar possiveis associacoes entre as variaveis perinatais e DPM. Metodos: Estudo...
Cow’s milk protein allergy (CMPA) is the leading cause of food in children under three years age, although its gastrointestinal manifestations may occur all age groups. In suspicion CMPA based on anamnesis and physical examination, an elimination diet should be initiated for a variable length time according to clinical picture, followed by oral challenge (OFC) confi rming or excluding diagnosis. Complementary exams such as skin prick tests specifi c IgE necessary. Treatment demands...
Chronic hepatic disease can present with extrapyramidal symptoms. We describe two cases that presented highly unusual movement disorders: ballism and gait freezing.Patient 1 is a 42-year-old man previous episodes of encephalopathy (HE) who upper limb dystonia generalized chorea progressed to ballism. Patient 2 55-year-old woman pronounced freezing. In both patients, features HE acquired hepatocerebral degeneration coexisted. They improved markedly, though transiently,...
Introduction: Craniopharyngiomas (CP) are tumors in the sellar region that, despite a high survival rate, associated with significant morbidity, including hypothalamic, hormonal, and visual dysfunction. This study aimed to assess quality of life (QoL) pediatric patients CP evaluate its relationship various factors, focus on impact endocrine Methods: In this observational cross-sectional study, aged between 0 18 years, currently followed up tertiary hospital by multidisciplinary team, were...
<strong>Background:</strong> Chronic hepatic disease can present with extrapyramidal symptoms. We describe two cases that presented highly unusual movement disorders: ballism and gait freezing. <strong>Case report:</strong> Patient 1 is a 42-year-old man previous episodes of encephalopathy (HE) who upper limb dystonia generalized chorea progressed to ballism. 2 55-year-old woman pronounced In both patients, features HE acquired hepatocerebral degeneration coexisted. They improved markedly,...
The association between glycemic control and metabolic status is poorly defined in children adolescents with T1D, besides being biologically plausible. We aimed to evaluate the body mass index (BMI), blood pressure (BP), lipid profile T1D.Observational cross-sectional study including (5-18 years old) followed our outpatient clinic diagnosis of T1D for at least a year. used linear regression models (unadjusted adjusted sex age) glycated hemoglobin (A1c) time range (TIR), several prespecified...
Introducao: O consumo abusivo de substâncias como alcool, medicamentos ou drogas ilicitas em adolescentes tem uma incidencia cada vez maior idades mais precoces. alcool e a substância comummente implicada intoxicacoes voluntarias adolescentes, sendo que maioria destes consumos ocorre durante convivio social. As sao causa frequente recorrencia ao Servico Urgencia (SU) importante morbilidade. objetivo deste trabalho caracterizar as recorreram SU do Centro Hospitalar Entre Douro Vouga (CHEDV)...
Introduction: SHOX gene (short stature homeobox gene) deficiency is one of the most frequent genetic causes isolated or familial short stature, with highly variable clinical severity.Case-report: The authors describe a 14 year-old-girl, limbs and stature. wrist X-ray showed Madelung deformity. molecular study deletion (FISH del (X) (Xp22.3Xp22.3) (SHOX). A very careful physical examination, including measurement body proportions, extreme importance in evaluation deformity can only appear...
A urticária aquagénica é uma forma rara de física, precipitada pelo contacto da água com a pele, independentemente sua temperatura e natureza. fisiopatologia não está completamente esclarecida. Descreve-se o caso criança observada na consulta aos 6 anos por lesões pele maculopapulares eritematosas vezes palidez associada, que surgiam especialmente no tórax, membros superiores inferiores quando contactava água, origem desta. Nessa altura colocou- -se como hipótese diagnóstico aquagénica....
Exercise is determinant to the management of type 1 diabetes mellitus.Despite being crucial for a healthy development, it brings several challenges patients, families and professionals that deal with insulin therapy.In fact, type, duration, intensity exercise (among other factors) can have an important impact on glycemic control.For reason, this paper aims present overview some basic concepts related in children adolescents diabetic will be useful clinicians develop effective enables...