A5082718557- Electroconvulsive Therapy Studies
- Alzheimer's disease research and treatments
- Transcranial Magnetic Stimulation Studies
- Neurological Disorders and Treatments
- Bipolar Disorder and Treatment
- Obsessive-Compulsive Spectrum Disorders
- Dementia and Cognitive Impairment Research
- Advanced Glycation End Products research
- Literature, Culture, and Criticism
- Religion, Spirituality, and Psychology
- Psychedelics and Drug Studies
- Biochemical Analysis and Sensing Techniques
- S100 Proteins and Annexins
- Natural Compound Pharmacology Studies
- Dietary Effects on Health
- Attention Deficit Hyperactivity Disorder
- Synthesis and Biological Evaluation
- Synthesis and biological activity
- Linguistics and Education Research
- Pain Management and Treatment
- Neurology and Historical Studies
- Adolescent and Pediatric Healthcare
- Context-Aware Activity Recognition Systems
- Maternal Mental Health During Pregnancy and Postpartum
- Neurological disorders and treatments
Universidade Federal Fluminense
2025
University of Coimbra
2014-2023
Hospitais da Universidade de Coimbra
2016-2019
Universidade Nova de Lisboa
2019
Newcastle University
2012
Newcastle Hospitals - Campus for Ageing and Vitality
2012
Background: Cerebrospinal fluid (CSF) measures of tau and amyloid proteins have now been largely accepted to be a diagnostic tool aid the clinical diagnosis Alzheimer's disease (AD), but CSF is not routinely obtained in most settings. There need, therefore, uncover additional readily accessible peripheral biomarkers that will enable comprehensive detection AD-specific blood derivates. Objectives: Blood platelets contain found neuronal cell lines, including protein. Since protein...
Background Clusterin protein in plasma has been found to differentiate between people with and without cognitive changes. However, these findings are not conclusive, despite the clusterin gene variations repeatedly being linked increased risk for dementia, particular Alzheimer's disease (AD). Method We analysed level of platelet 25 subjects a clinical diagnosis AD 26 no impairment. Results In current study, we report that levels both similar cognitively intact individuals. levels, as well...
Background: the diagnosis of dementia, in particular Alzheimer's disease (AD), is enhanced with use molecular biomarkers. Since cerebrospinal fluid analysis and neuroimaging are not routinely used many countries, blood biomarker molecules may be more readily applicable a routine clinical setting. Methods: twenty-five subjects AD 26 control participants were assessed for cognitive behavioural functioning. Platelet measures amyloid protein precursor (APP), tau protein, clusterin, α-synuclein...
Currently there are no effective treatments available for dementia. Attention has turned to defining preventive strategies and identifying modifying effects of lifestyle, including physical activity, diet, alcohol intake smoking, in reducing cognitive decline overt memory problems the elderly.In this study, we addressed aspects various components lifestyle two ageing samples explored possible that exercise, diet spiritual religious beliefs have upon mental health. A total 251 subjects (128...
We report a 16.5% increase in platelet immunoglobulin (Ig) content subjects with Alzheimer's disease (AD) relation to cognitively intact individuals (p = 0.021), whereas the plasma Ig levels were unaltered 0.428). The upregulation of plate
Introduction Obsessive-compulsive disorder (OCD) has high rates of comorbidity with mood disorders, mainly major depressive (MDD). Symptoms depression are usually secondary to severe and disabling OCD. Electroconvulsive therapy (ECT) been an effective well tolerated therapeutic alternative in the management refractory MDD. Other neuromodulation techniques, such as repetitive transcranial magnetic stimulation (rTMS), have known efficacy MDD also shown positive results, clinical trials,...
Abstract Artificial Intelligence is driving a revolution in the most diverse domains of computational services and user interaction. Data collected large quantities becoming useful for feeding intelligent systems that analyse, learn provide insights help decision support systems. Machine learning usage algorithms are importance to extract features, reason over data so it becomes preventive, exposing discoveries augmenting knowledge about processes. Human driven applications, as those related...
Introduction OCD could be a very disabling condition, implying severe impairment of social and occupational functioning decreased quality life. is treated with combination psychopharmacological treatments cognitive-behavioural therapy. Clomipramine was the first anti-obsessive drug, followed by selective serotonin re-uptake inhibitors (SSRIs), both modulating serotoninergic transmission. Low dose atypical anti-psychotic are sometimes used to potentiate agents. Growing evidence based on...
Introduction Transcranial Magnetic Stimulation (TMS) is a non-invasive neuromodulation tool with growing body of clinical evidence demonstrating positive outcomes in patients treatment-resistant depression (TRD) as sole or adjuvant therapy. Theta-burst stimulation (TBS), specifically intermittent TBS (iTBS), uses short pulse trains to cut each session’s duration 10% the original repetitive TMS protocol sessions, making it more appealing option given that shows similar efficacy. Nevertheless,...