Yong Gao

ORCID: 0000-0001-7962-7196
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About
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Research Areas
  • Advanced Polymer Synthesis and Characterization
  • Pickering emulsions and particle stabilization
  • Surfactants and Colloidal Systems
  • Polymer Surface Interaction Studies
  • Nanoplatforms for cancer theranostics
  • Polymer Nanocomposites and Properties
  • Conducting polymers and applications
  • Luminescence and Fluorescent Materials
  • Advanced Condensed Matter Physics
  • Proteins in Food Systems
  • Carbon Nanotubes in Composites
  • Molecular Sensors and Ion Detection
  • Advanced biosensing and bioanalysis techniques
  • Hydrogels: synthesis, properties, applications
  • Advanced Nanomaterials in Catalysis
  • Electrochemical sensors and biosensors
  • Physics of Superconductivity and Magnetism
  • Advanced Cellulose Research Studies
  • biodegradable polymer synthesis and properties
  • Photochromic and Fluorescence Chemistry
  • Electrochemical Analysis and Applications
  • Magnetic and transport properties of perovskites and related materials
  • Advanced Sensor and Energy Harvesting Materials
  • Bone Tissue Engineering Materials
  • Synthesis and properties of polymers

Zhejiang University
2023-2024

University of Hong Kong
2020-2024

Huazhong University of Science and Technology
2023-2024

Changzhou University
2022-2024

Northwestern Polytechnical University
2024

Hebei University of Science and Technology
2024

Union Hospital
2023-2024

Fujian Normal University
2022-2023

State Key Laboratory of Surface Physics
2019-2022

Fudan University
2008-2022

Bacterial infection is one of the greatest challenges to public health, requiring new therapeutic methods. Herein, an innovative nanozyme-armed phage (phage@palladium (Pd)) system fabricated for combating bacterial infection. The proposed phage@Pd preserves function phages achieve precise recognition and adhesion host Escherichia coli. In aid phages, ultrasmall Pd nanozymes equipped with conspicuous pH-dependent peroxidase-like activity can generate toxic hydroxyl radical around bacteria in...

10.1002/adma.202301349 article EN Advanced Materials 2023-04-21

Electrochemistry offers a sustainable synthesis route to value-added fine chemicals but is often constrained by competing electron transfer between the electrode and redox-sensitive functionalities distinct from target site. Here, we describe an ion-shielding heterogeneous photoelectrocatalysis strategy impose mass-transfer limitations that invert thermodynamically determined order of transfer. This showcased enable decarboxylative trifluoromethylation sensitive (hetero)arenes using...

10.1126/science.adm8902 article EN Science 2024-05-09

10.1016/j.physrep.2024.03.004 article EN Physics Reports 2024-04-04

Background:The current clinical treatment of osteomyelitis is limited by the emergence drug-resistant bacteria, which often leads to failure traditional antibiotic and large bone defects.Sonodynamic therapy (SDT) a new strategy that widely used overcome problem bacterial resistance as well poor tissue penetration using near-infrared light in photodynamic (PDT).Therefore, it necessary develop sonosensitizer can kill bacteria promote repair.Methods: Herein, we developed sonosensitizer,...

10.7150/thno.81511 article EN cc-by Theranostics 2023-01-01

A kind of manipulative oil in water Pickering emulsion stabilized by heterogeneously modified cellulose nanocrystals (CNCs) and its application as a template for the creation functional polystyrene microspheres were presented this study. First, 18-carbon alkyl long chains selectively introduced at reducing ends CNCs through two-step chemical process including hydrazone reaction amidation reaction. The as-obtained (CNC–C18) then used emulsifiers formation emulsions. Compared with pristine...

10.1021/acssuschemeng.7b00375 article EN ACS Sustainable Chemistry & Engineering 2017-07-31

Abstract Switchable organic fluorescent materials are attracting much interest in many fields including flexible display, information storage, anti‐counterfeit, and bioimaging, due to their prominent properties relatively low cost. Herein, a class of novel photoswitchable polymeric nanoparticles (PFPNs) toolbox that shows switchable full‐colored emission white light is described. This consists series reversibly non‐PFPNs with red, green, blue fluorescence, built up from three primary dyes...

10.1002/adfm.201804759 article EN Advanced Functional Materials 2018-10-01

The neuroinflammatory responses following ischemic stroke cause irreversible nerve cell death. Cell free-double strand DNA (dsDNA) segments from tissue debris are engulfed by microglia and sensed their cyclic GMP-AMP synthase (cGAS), which triggers robust activation of the innate immune stimulator interferon genes (STING) pathway initiate chronic inflammatory cascade. decomposition immunogenic dsDNA inhibition STING synergistic immunologic targets for ameliorating neuroinflammation. To...

10.1016/j.bioactmat.2023.07.002 article EN cc-by Bioactive Materials 2023-07-18

Probiotics have the potential as biotherapeutic agents for cancer management in preclinical models and human trials by secreting antineoplastic or immunoregulatory tumor microenvironment (TME). However, current probiotics lack ability to dynamically respond unique TME characteristics, leading limited therapeutic accuracy efficacy. Although progress has been made customizing controllable through synthetic biology, engineering process is complex predictability of production relatively low. To...

10.1002/adma.202304257 article EN Advanced Materials 2023-10-04

Abstract Background Most bone defects caused by disease or trauma are accompanied infection, and there is a high risk of infection spread defect expansion. Traditional clinical treatment plans often fail due to issues like antibiotic resistance non-union bones. Therefore, the infected requires strategy that simultaneously achieves antibacterial efficiency promotes regeneration. Results In this study, an ultrasound responsive vanadium tetrasulfide-loaded MXene (VSM) Schottky junction...

10.1186/s12951-023-02283-6 article EN cc-by Journal of Nanobiotechnology 2024-01-16

Abstract Herein, a class of novel photoswitchable tristate fluorescent polymeric nanoparticles (TS‐PFPNs) consisting well‐designed perylenediimide‐spiropyran conjugate (PDI‐SP), two energy‐matched photochromics as spiropyran‐linked methacrylate and diarylethene (DTE) derivative (DTEo‐1) is described. By optimizing the feed ratio three dyes controllable switching fluorescence resonance energy transfer from excited PDI to SP or DTE moiety with different lights stimuli, emission these TS‐PFPNs...

10.1002/adom.202101227 article EN Advanced Optical Materials 2021-09-04

The asymmetric total syntheses of four pleurotin natural products, namely, (−)-pleurotin, (+)-leucopleurotin, (+)-leucopleurotinic acid, and (+)-dihydropleurotinic were described in a concise manner. Key transformations feature Johnson–Claisen rearrangement, diastereo-controlled sequential hydroboration-oxidation, SOMO/photoredox activated aldehyde α-alkylation, oxidative cyclizations.

10.1021/jacs.4c06746 article EN Journal of the American Chemical Society 2024-06-26

10.1016/j.colsurfa.2017.06.056 article EN Colloids and Surfaces A Physicochemical and Engineering Aspects 2017-06-22

10.1016/j.saa.2013.12.098 article EN Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy 2014-01-04
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