A5066493488- Natural product bioactivities and synthesis
- Traditional and Medicinal Uses of Annonaceae
- Ginger and Zingiberaceae research
- Phytochemistry and Bioactive Compounds
- Phytochemistry and Biological Activities
- Piperaceae Chemical and Biological Studies
- Essential Oils and Antimicrobial Activity
- Plant biochemistry and biosynthesis
- Phytochemical Studies and Bioactivities
- Medicinal Plants and Neuroprotection
- Biological and pharmacological studies of plants
- Phytochemistry and Bioactivity Studies
- Phytochemical compounds biological activities
- Biological Activity of Diterpenoids and Biflavonoids
- Marine Sponges and Natural Products
- Oil Palm Production and Sustainability
- Coastal wetland ecosystem dynamics
- Chromatography in Natural Products
- Pharmacological Effects of Medicinal Plants
- Polysaccharides and Plant Cell Walls
- Computational Drug Discovery Methods
Hue University of Agriculture and Forestry
2020-2025
Hue University
2017-2025
A new 14-membered cembrane-type diterpenoid, jatrophainolide D (1), along with six known compounds, (E)-phytol (2), lupeol (3), stigmasterol (4), ergosta-4,6,8 (14),22-tetraen-3-one (5), stigmast-4-ene-3-one (6), and ergosterol peroxide (7) were isolated from the aerial parts of Jatropha integerrima. The structure isolates was elucidated by IR, UV, 1D-/2D-NMR, HRESI-TOFMS data as well comparison reported spectroscopic data. All evaluated antibacterial activity against S. enterica, E. coli,...
Distichochlamys benenica is a native black ginger that grows in Vietnam. In point of fact, there limitation available information the literature making mention chemical constituents and bioactive properties this plant. This study aimed at isolating trans-o-coumaric acid (1), trans-cinnamic (2), borneol (3) from rhizomes D. Q.B.Nguyen & Škorničk evaluate anti-inflammatory antimicrobial activities 1-3 using carrageenan paw edema model dilution broth method, respectively. revealed 1 was as...
Sixteen sesquiterpenoids including two new ones, homalolides A - B (1‒2), were firstly isolated from the methanolic extract of rhizomes Homalomena pendula collected in Vietnam. The structures and relative stereochemistry compounds elucidated by 1D-/2D-NMR, IR, UV HRESIMS analyses. GCMS experiment demonstrated that homalolide (1) is an artifact due to methylation during extraction process. All isolates (1‒16) tested for their inhibitory activities against lipopolysaccharide-induced nitric...
The aim of the research was to study active constituents Anodendron paniculatum Roxb. (Apocynaceae). A new triterpene ester, named anopaniester (1), and cycloartenol (2), ursolic acid (3), esculenic (4), bis-(2-ethylhexyl) phthalate (5), desmosterol (6), stigmasterol (7), vaniline (8), (E)-phytol (9), were isolated from aerial parts A. paniculatum. Compounds 3 6 showed significant inhibitory effect (IC50 values ranging 30.89 ± 3.60 44.37 5.40 μg/ml) against tested human cancer cell lines...
Four novel compounds, conarubins A–D (1–4), were isolated from the whole plants of Conamomum rubidum collected in Vietnam. Their structures elucidated by extensive spectroscopic analyses and quantum chemical calculations NMR ECD. Compounds 1 2 first examples monoterpene–monoterpene–chalcone conjugates nature, whereas compound 4 was an unprecedented monoterpene-substituted chalcone containing a 3,4,5-trioxygenated cyclohexa-2,5-diene-1-one ring. The anti-inflammatory cytotoxic activities all...
A new compound, conamonin (
Two new sesquiterpenoids, homalolides C − D (1‒2), were co-isolated from the rhizomes of Homalomena pendula (Blume) Bakh.f collected in Vietnam with five known ones, aromadendrane-4α,10α-diol (3), bullatantriol (4), 1β,4β,6α-trihydroxy-eudesmane (5), 1β,4β,6β-trihydroxyeudesmane (6), and 1β,4β,7α-trihydroxy-eudesmane (7). The structures relative configuration compounds elucidated by 1 D-/2D-NMR, IR, UV HRESIMS analyses, comparisons to reported data literature. Homalolide presented an...
Five sesquiterpenoids including 2α-hydroxyoplopanone (1), oplopanone (2), 1β,4β,6α-trihydroxy-eudesmane (3), 1β,4β,7α-trihydroxy-eudesmane (4) and bullatantriol (5) were isolated from Homalomena pendula. The structure of the previously reported compound, 5,7-diepi-2α-hydroxyoplopanone (1a), has been revised to 1 by spectroscopic evidences (1D-/2D-NMR, IR, UV HRESIMS) comparison between experimental theoretical NMR data using DP4+ protocol. Furthermore, absolute configuration was...
Objectives: This study aims to evaluate the cytotoxicity of compounds isolated from Buxus latistyla Gagnep. against selected cell lines. Methods: The isolation process was carried out using combined chromatographic techniques. structural elucidation achieved by combining 1D-/2D-NMR and HRESIMS data. absolute configurations new were also confirmed ECD experiments. sulforhodamine B colorimetric assay employed assess toxicity isolates tested Results: Two lupane-type derivatives, 3...
Lung cancer stands out as a leading cause of death among various types, highlighting the urgent need for effective anticancer drugs and discovery new compounds with potent therapeutic properties. Natural sources, such
Objective: This study aimed to analyze the essential oil obtained from Litsea balansae Lecomte leaves and investigate its potential as an anti-inflammatory antioxidant agent. Methods: Fresh L were collected in Quangtri, Vietnam, subjected hydro-distillation using a Clevenger-type apparatus extract oil. The composition was analyzed gas chromatography–mass spectrometry (GC-MS). Antioxidant capacity evaluated through 2,2-Diphenyl-1-picrylhydrazyl assay, while inhibition of nitric oxide...
A phytochemical investigation of whole Aspidistra letreae plants led to the isolation 2H-chromen-2-one (1), α-tocopherol (2), (E)-phytol (3), asparenydiol (4) and (25S)-spirost-1β,3α,5β-triol (5). Their structures were determined on basis NMR spectral evidences in comparison with reported data. Of these, was isolated from genus for first time. This is also report separation structural determination (5) as a pure compound. The methanol extract exhibits moderate cytotoxicity against LU-1,...