Piper lolot is a species of herb used as popular food in Vietnam. Furthermore, the has been Vietnamese traditional medicine to treat many diseases.Chemical constituents essential oil from leaves were determined using GC/MS analysis. The anti-gout and anti-diabetic activities through inhibitory assays against xanthine oxidase, α-glucosidase α-amylase enzymes. In addition, molecular docking simulations elucidate mechanism between main compounds enzymes.The dominant oils β-caryophyllene...

Using various chromatographic separations, four compounds, including one new steroid saponin named vernoamyoside E (1), were isolated from the leaves of Vietnamese medicinal plant Vernonia amygdalina Delile (Asteraceae). Their structures established by spectroscopic methods such as 1D- and 2D-NMR, HR-ESI-MS, HPLC analysis. The inhibitory activities against α-glucosidase α-amylase compounds V. reported for first time. results indicated that compound 1 significantly inhibited both activity.

Two new lignans (7S,7'R,8S,8'R)-3,3'-dimethoxy-7,7'-epoxylignan-4,4',9-triol 4-O-β-D-glucopyranoside (1) and 9-O-formylaviculin (2) together with other thirteen known secondary metabolites were isolated from the leaves of Antidesma hainanensis. Their chemical structures determined using NMR, electrospray ionization (ESI)-MS, circular dichroism (CD) spectroscopic methods, as well by comparison those reported in literature. Neuro-inflammatory activity compounds was evaluated their inhibition...

Hypericum sampsonii is an important medicinal plant used in Vietnam to treat many diseases such as backache, burns, diarrhea, and swelling. In order study the chemical constituents aerial parts of H. sampsonii, five compounds, including two xanthones (1–2), three benzophenones (3–5) were isolated from with various chromatographic separations. Their structures established on basis spectroscopic data 1D- 2D-NMR, HR-ESI-MS. anti-inflammatory activities investigated by measuring nitric oxide...

A new compound, conamonin (

Two planthopper species of the family Nogodinidae are added to fauna Vietnam, both from two localities in Thua Thien-Hue Province: Bach Ma National Park and Phong Dien District. The first belongs Goniopsarites Meng, Wang & Wang, 2014, G. mientrunganus Constant Pham, sp. nov. , second Pisacha Distant, 1906, P. yinggensis 2014. was previously recorded Hainan Island, China. These new records greatly extend distribution genera, which were known southern China, North south, reaching mid area...

A phytochemical investigation of Physalis minima led to the isolation six withanolides, including withanolide E (1), withaperuvin C (2), 4β-hydroxywithanolide (3), 28-hydroxywithaperuvin (4), physaperuvin G (5), and 4-deoxywithaperuvin (6). Their chemical structures were elucidated by 1 D-NMR 2 data, as well comparison with data reported in literature. All isolated compounds evaluated for their cytotoxic activity against HepG2, SK-LU-1, MCF7 cancer cell lines. As obtained results, 3...

Industrial wastewater often consists of toxic chemicals and pollutants, which are extremely harmful to the environment. Heavy metals considered one major hazards aquatic ecosystem. Analytical techniques, such as potentiometric methods, some methods detect heavy in wastewaters. In this work, quantitative structure–property relationship (QSPR) was applied using a range machine learning techniques predict stability constant (logβML) sensitivity (PSML) 200 ligands complexes with metal ions Cu2+,...

Mangrove plant endophytic bacteria are prolific sources of bioactive secondary metabolites. In the present study, twenty-three were isolated from fresh roots mangrove Rhizophora apiculata. The identification isolates by 16S rRNA gene sequences revealed that belonged to nine genera, including Streptomyces, Bacillus, Pseudovibrio, Microbacterium, Brevibacterium, Microbulbifer, Micrococcus, Rossellomorea, and Paracoccus. ethyl acetate extracts bacteria’s pharmacological properties evaluated in...

A new ursane-type triterpene, 3β,23,24-trihydroxyurs-12-en-28-oic acid (1), together with eight known compounds (2-9) were isolated from the aerial parts of Ophiorrhiza baviensis. Among them, 2-5 found for first time genus Ophiorrhiza, while 6-9 reported O. baviensis time. Their structures elucidated by analysis HR-ESI-MS and NMR (1H-NMR, 13C-NMR, HSQC, HMBC) spectra, as well comparison those in literature. Moreover, all evaluated their cytotoxic activities against MCF-7, Hela, KB, A549,...

A new steroidal saponin, torvoside R (1), was isolated along with Q (2) and macaoside (3) from dichloromethane soluble-portion of the aerial parts Solanum torvum. Their chemical structures were elucidated using HRESIMS, 1 D- 2 D-NMR as well comparison those reported in literature. All compounds (1 - 3) exhibited cytotoxicity against SK-LU-1, HepG2, MCF-7, T24 cancer cell lines IC50 values ranging 14.18 to 89.31 µg/mL.

In this study, chemical components, α-glucosidase inhibitory activities, and molecular modelling studies of the essential oil extracted from Cleistocalyx operculatus leaves were investigated. total, thirty compounds identified using GC/MS, representing 98.3% oil. Of these, two most dominant constituents determined as (Z)-β-ocimene (30.4%) allo-ocimene (31.6%). The experiments indicated that exhibited potent with IC50 values 61.82 ± 3.91 µg/mL. For further investigation into mechanisms,...

Using various chromatographic methods, two new alkaloids, antidesoic acids A (1) and B (2) along with fourteen known compounds (3-16) were isolated from the leaves of Antidesma ghaesembilla Gaertn. Their chemical structures elucidated by physical methods. All evaluated for their inhibitory activity on LPS-stimulated nitric oxide (NO) production in BV2 cells RAW 264.7 macrophages. Bisflavone 8 significantly inhibited LPS- stimulated NO macrophages IC₅₀ values 5.4 8.0 μM, respectively....

Abstract In this article, four secosteroids, including physalin B ( 1 ), D 2 F 3 and G 4 ) were isolated from the dichloromethane extract of P. angulata growing in Thai Binh, Vietnam by using various chromatographic methods. Their chemical structures determined analyses 1D 2D‐NMR spectral data as well comparison with those published literature. Anti‐microbial assays showed that compounds ‐ exhibited anti‐microbial against a panel clinically significant microorganisms MIC values 32 to 128 μg/mL.

A phytochemical investigation of Solanum torvum led to the isolation eleven steroidal glycosides, including neochlorogenin 6-O-β-D-quinovopyranoside (1), (22 R,23S,25R)-3β-6α,23-trihydroxy-5α-spirostane 6-O-β-D-xylopyranosyl-(1→3)-β-D-quinovopyranoside (2), 6-O-α-L-rhamnopyranosyl-(1→3)-β-D-quinovopyranoside (3), solagenin (4), paniculonin (5), B (6), 6α-O-[β-D-xylopyranosyl-(1→3)β-D-quinovopyranosyl]-(25S)-5α-spirostan-3β-ol (7), torvoside J (8), K (9), L (10) and (11). Their chemical...

Chemical investigation of the methanol extract aerial parts Buddleja asiatica resulted in isolation a new iridoid glycoside, buddlejasiaside A (1) and 11 known compounds: 6- O -[α-L-(4-isoferuloyl)-rhamnopyranosylcatalpol (2), specioside (3), verminoside (4), minecoside (5), -( p -hydroxybenzoyl)-ajugol (6), -caffeoyl ajugol (7), litanthosalin 8), eurostoside (9), 10- -caffeoylaucubin (10), phlorizin (11), garashangin (12). Their chemical structures were identified based on MS NMR...

Abstract From the dichloromethane extract of whole plant P. angulata growing in Vietnam, three withanolides including physagulin L ( 1 ), M 2 and withaminimin 3 ) were isolated by using various chromatography methods. Their chemical structures determined detailed analysis 1D 2D‐NMR data comparison with reported data. All compounds tested for their inhibitory activities against NO production LPS‐stimulated RAW 264.7 macrophages. The results showed that compound had a weak anti‐inflammatory...

Background: Traditional Chinese medicines have attracted increasing interest as potential sources of novel drugs with a wide range biological and pharmacological activities. The leaves Antidesma acidum Retz. were used in traditional medicine for treatment stomachache children, digestion related issues diabetes. Moreover, phytochemical investigations this plant confirmed the presence alkaloids, triterpenes, flavonoids. Methods: Using chromatographic methods to isolate compounds from methanol...

In the present study, rare true bug Bannacoris hyalinus (Schaefer & Ashlock, 1970), comb. nov. (Hemiptera, Heteroptera, Pentatomomorpha, Pentatomoidea, Saileriolidae), which is endemic to Vietnam, redescribed and transferred from genus Saileriola China Slater, 1956 Hsiao, 1964 based on morphological characteristics. Adults nymphs of this species congregate in groups several individuals suck sap abaxial side leaves Litsea sp. (Lauraceae). They cause visible feeding damage adaxial leaves,...

Two new planthopper species of the tropiduchid genus Connelicita Wang & Bourgoin, 2015, C. bachmaensis Constant Pham, sp. nov. , and phongdienensis are described from Bach Ma National Park Centre for Conservation Vietnam Natural Resources Rescue Animals plants, Phong Dien District in Thua Thien-Hue Province, respectively. These records greatly extend distribution genus, which was known southern China (Guangxi) North Vietnam, to south, reaching mid area Central Vietnam. New provided...

Entada phaseoloides (L.) Merr. belongs to Fabaceae family and widely distributes throughout Vietnam, Thailand, Malaysia, Indonesia, Philippines, China, New Guinea, Australia. In Vietnamese traditional medicine, the seeds of were used for treatment stomachache, haemorrhoids, hernia diseases. this article, we report isolation structural elucidation four glycosides from water extract E. including phaseoloideside C (1), E (2), acanthoside D (3),...