A5009176114- SARS-CoV-2 and COVID-19 Research
- Essential Oils and Antimicrobial Activity
- Biochemical and Structural Characterization
- Computational Drug Discovery Methods
- COVID-19 Clinical Research Studies
- Medicinal Plant Research
- Phytochemicals and Antioxidant Activities
- SARS-CoV-2 detection and testing
- Andrographolide Research and Applications
- Natural product bioactivities and synthesis
- Plant-derived Lignans Synthesis and Bioactivity
- Toxin Mechanisms and Immunotoxins
- Phytochemical compounds biological activities
- Diverse Scientific Research Studies
- Phytochemistry and Bioactive Compounds
Universidad Nacional de Asunción
2022-2024
The COVID-19 pandemic has led to the search for new molecules with antiviral activity against SARS-CoV-2. entry of virus into cell is one main targets inhibiting SARS-CoV-2 infection. Natural products are an important source therapeutic alternatives diseases. Pseudotyped viruses allow study viral inhibitors, and due their simplicity, they screening a large number candidates in Biosafety Level 2 facilities. We used pseudotyped HIV-1 D614G spike glycoprotein test its ability infect...
Medicinal herbs have long been utilized to treat various diseases or relieve the symptoms of some ailments for extended periods. The present investigation demonstrates phytochemical profile, molecular docking, anti-Candida activity, and anti-viral activity Saussurea costus acetic acid extract. GC-MS analysis extract revealed presence 69 chemical compounds. compounds were alkaloids (4%), terpenoids (79%), phenolic hydrocarbons (7%), sterols (6%). Molecular docking was used study inhibitory...
The chemical composition of extracts (CEs) and essential oils (EOs) from Tetradenia riparia leaves, flower buds, stems was analyzed. Antiproliferative activity against tumor cell lines, NO production inhibition, antioxidant antiviral activities were assessed. CEs contained flavonoids, phenolic acids, coumarins, saturated fatty acids. EOs included monoterpenes, oxygenated sesquiterpenes, diterpenes. inhibition ranged 76 to 247 µg mL−1, antiproliferative exhibited GI50 between 20 >204 with...
Siddha medicine is one of the oldest medical systems in world and believed to have originated more than 10,000 years ago prevalent across ancient Tamil land. It undeniable that inhibitor preferences rise with increasing solubility water due considerations pertaining bioavailability ease which unabsorbed residues can be disposed of. In this study, we showed phytochemical discrimination Saussurea costus extracted at room temperature as a green extraction procedure. A total 48 compounds were...
Severe Acute Respiratory Syndrome-Coronavirus-2 Virus (SARS-CoV-2) is responsible for Coronavirus Disease 2019 (COVID-19). A substantial number of SARS-CoV-2 infection cases have been reported during the pandemic, and vaccination coverage in some regions, particularly developing countries, remains very low. variants concern (VOCs) also emerged as most pressing public health issues. In this scenario, it crucial to know whether COVID-19 convalescent antibodies cross-neutralizing action against...