A5046728330- COVID-19 and healthcare impacts
- Healthcare cost, quality, practices
- COVID-19 Clinical Research Studies
- Vaccine Coverage and Hesitancy
- SARS-CoV-2 and COVID-19 Research
- SARS-CoV-2 detection and testing
- Long-Term Effects of COVID-19
- Venous Thromboembolism Diagnosis and Management
- COVID-19 Impact on Reproduction
- Medical Coding and Health Information
- Health and Medical Research Impacts
- Chronic Disease Management Strategies
- Muscle and Compartmental Disorders
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Healthcare Systems and Challenges
- Religious Studies and Spiritual Practices
- Biomedical and Engineering Education
- Chronic Lymphocytic Leukemia Research
- Quality and Safety in Healthcare
- Acute Myocardial Infarction Research
- Cardiac Imaging and Diagnostics
- Heparin-Induced Thrombocytopenia and Thrombosis
- Blood groups and transfusion
- Cardiovascular Effects of Exercise
- Peripheral Neuropathies and Disorders
International Biometric Society
2024
IBM (United States)
2020-2022
Mental Health Commission
2010
Pregnancy outcome identification and precise estimates of gestational age (GA) are critical in drug safety studies pregnant women. Validated pregnancy algorithms based on the International Classification Diseases, Tenth Revision, Clinical Modification/Procedure Coding System (ICD-10-CM/PCS) have not previously been published.
Preventable errors are common in healthcare. Over the last decade, Root Cause Analysis (RCA) has become a key tool for healthcare services to investigate adverse events and try prevent them from happening again. The purpose of this paper is highlight work New South Wales (NSW) RCA Review Committee. benefits correctly classifying, aggregating disseminating data clinicians will be discussed. In NSW, we perform an average 500 RCAs per year. It estimated that each takes between 20 90 h perform....
The U.S. Food and Drug Administration (FDA) Biologics Effectiveness Safety (BEST) Initiative conducts active surveillance of adverse events special interest (AESI) after COVID-19 vaccination. Historical incidence rates (IRs) AESI are comparators to evaluate safety.We estimated IRs 17 in six administrative claims databases from January 1, 2019, December 11, 2020: Medicare for adults ≥ 65 years commercial (Blue Health Intelligence®, CVS Health, HealthCore Integrated Research Database, IBM®...
Healthcare administrative claims data hold value for monitoring drug safety and assessing effectiveness. The U.S. Food Drug Administration Biologics Effectiveness Safety Initiative (BEST) is expanding its analytical capacity by developing claims-based definitions-referred to as algorithms-for populations outcomes of interest. Acute myocardial infarction (AMI) was interest due potential association with select biologics the lack an externally validated International Classification Diseases,...
Claims-based algorithms are used in the Food and Drug Administration Sentinel Active Risk Identification Analysis System to identify occurrences of health outcomes interest (HOIs) for medical product safety assessment. This project aimed apply machine learning classification techniques demonstrate feasibility developing a claims-based algorithm predict an HOI structured electronic record (EHR) data.We 2015-2019 IBM MarketScan Explorys Claims-EMR Data Set, linking administrative claims EHR...
Aim: Understanding barriers and facilitators to pharmacogenomics (PGx) implementation how structure a clinical program with the Veterans Health Administration (VA). Materials & methods: Healthcare provider (HCP) survey at 20 VA facilities assessing PGx knowledge/acceptance qualitative interviews understand best design sustain national program. Results: 186 (12% response rate) surveyed believed informs drug efficacy (74.7%) adverse events (71.0%). Low confidence in knowledge (43.0%) ability...
Vaccine use during pregnancy affects maternal and infant health. Many women do not receive vaccines recommended pregnancy; conversely, inadvertent exposure to contraindicated or may occur. We assessed two among privately Medicaid-insured in the United States.This study includes a retrospective cohort of pregnancies aged 12-55 years resulting live birth, spontaneous abortion, stillbirth identified IBM® MarketScan® Commercial, Blue Health Intelligence® (BHI®) IBM MarketScan Multi-State...
The Food and Drug Administration’s Biologics Effectiveness Safety Initiative conducts active surveillance to protect public health during the coronavirus disease 2019 (COVID-19) pandemic. This study evaluated performance of International Classification Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) diagnosis code U07.1 in identifying COVID-19 cases claims compared with severe acute respiratory syndrome 2 (SARS-CoV-2) nucleic acid amplification test results linked electronic...
Abstract Background Longitudinal patterns of immune globulins (IG) use have not been described in large populations. Understanding IG usage is important given potential supply limitations impacting individuals for whom the sole life‐saving/health‐preserving therapy. The study describes US utilization from 2009 to 2019. Study Design and Methods Using IBM MarketScan commercial Medicare claims data, we examined four metrics overall by condition‐specific categories during 2009–2019: (1)...
COVID-19 infections have contributed to substantial increases in hospitalizations. This study describes demographics, baseline clinical characteristics and treatments, outcomes among U.S. patients admitted hospitals with during the prevaccine phase of pandemic. A total 20,446 hospitalized a positive nucleic acid amplification test were identified from three large electronic health record databases 5 February-30 November 2020 (Academic Health System: n = 4504; Explorys; 7492; OneFlorida:...
<title>Abstract</title> Background Many neurologic or immune-mediated conditions have been evaluated as potential adverse events (AEs) in coronavirus disease 2019 (COVID-19) vaccine safety surveillance. To contextualize United States (US) surveillance findings, it is important to quantify the risk of AEs associated with COVID-19 diagnosis among adults US before introduction vaccines. Methods Cohort and self-controlled interval (SCRI) designs were used 2 administrative claims data...
Abstract Purpose This study evaluated the association between coronavirus disease 2019 (COVID-19) diagnosis and adverse events (AEs), including cardiovascular AEs appendicitis, in US adults before introduction of COVID-19 vaccines. Real-world studies after suggest that diagnoses frequently occur on same day may be a source bias. Methods Cohort self-controlled risk interval (SCRI) designs were used 2 administrative claims data sources—Merative™ MarketScan® (ages 18-64 years) Medicare ≥ 65...
Thrombosis with thrombocytopenia syndrome (TTS) has been reported following receipt of adenoviral vector-based COVID-19 vaccines. However, no validation studies evaluating the accuracy International Classification Diseases-10-Clinical Modification (ICD-10-CM)-based algorithm for unusual site TTS are available in published literature.The purpose this study was to assess performance clinical coding 1) leverage literature review and input develop an ICD-10-CM-based identify as a composite...
Monitoring COVID-19 testing volumes and test positivity is an integral part of the response to pandemic. We described characteristics individuals who were tested positive for SARS-CoV-2 during pre-vaccine phase pandemic in United States (U.S.).This descriptive study analyzed three U.S. electronic health record (EHR) databases (Explorys, Academic Health System, OneFlorida) between February November 2020, identifying patients received interpretable nucleic acid amplification (NAAT) result....
Background: The U.S. Food and Drug Administration (FDA) Biologics Effectiveness Safety (BEST) Initiative conducts active surveillance of adverse events special interest (AESI) after COVID-19 vaccination. Historical incidence rates (IRs) AESI are comparators to evaluate safety.Methods: We estimated IRs 17 in six administrative claims databases from January 1, 2019, December 11, 2020: Medicare for adults ≥65 years commercial (Blue Health Intelligence®, CVS Health, HealthCore Integrated...