A5052817979- Gastroesophageal reflux and treatments
- Eosinophilic Esophagitis
- Esophageal and GI Pathology
- Helicobacter pylori-related gastroenterology studies
- Esophageal Cancer Research and Treatment
- Dysphagia Assessment and Management
- Acute Myocardial Infarction Research
- Coronary Interventions and Diagnostics
- Respiratory and Cough-Related Research
- Cardiac Arrhythmias and Treatments
- Cardiovascular Disease and Adiposity
- Ultrasound and Hyperthermia Applications
- SARS-CoV-2 and COVID-19 Research
- Cardiac pacing and defibrillation studies
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Cardiac Valve Diseases and Treatments
- Phagocytosis and Immune Regulation
- Anesthesia and Pain Management
- Pericarditis and Cardiac Tamponade
- Antiplatelet Therapy and Cardiovascular Diseases
- Enzyme function and inhibition
- Cardiac, Anesthesia and Surgical Outcomes
- Myasthenia Gravis and Thymoma
- Neuroendocrine Tumor Research Advances
- dental development and anomalies
Michigan Medicine
2024
Northwestern University
2015-2021
Illinois College
2020-2021
University of Illinois Chicago
2020-2021
University of Illinois Urbana-Champaign
2020
Northwestern Medicine
2019
Craft Engineering Associates (United States)
2016
Tufts University
1961
Esophagogastric junction (EGJ) distensibility and distension-mediated peristalsis can be assessed with the functional lumen imaging probe (FLIP) during a sedated upper endoscopy. We aimed to describe esophageal motility assessment using FLIP topography in patients presenting dysphagia.In all, 145 (aged 18-85 years, 54% female) dysphagia that completed endoscopy 16-cm assembly high-resolution manometry (HRM) were included. HRM was analyzed according Chicago Classification of disorders; major...
INTRODUCTION: To compare the utility of distensibility index (DI) on functional lumen imaging probe (FLIP) topography to other esophagogastric junction (EGJ) metrics in assessing treatment response achalasia context esophageal anatomy. METHODS: We prospectively evaluated 79 patients (at ages 17–81 years; 47% female patients) with during follow-up after pneumatic dilation, Heller myotomy, or per-oral endoscopic myotomy timed barium esophagram, high-resolution impedance manometry, and FLIP....
We aimed to evaluate the value of novel high-resolution impedance manometry (HRIM) metrics, bolus flow time (BFT), and esophagogastric junction (EGJ) contractile integral (CI), as well EGJ pressure (EGJP) integrated relaxation (IRP), indicators treatment response in achalasia.We prospectively evaluated 75 patients (ages 19-81, 32 female) with achalasia during follow-up after pneumatic dilation or myotomy Eckardt score (ES), timed-barium esophagram (TBE), HRIM. Receiver-operating...
Abstract Background There is a need to identify factors outside of abnormal reflux that contribute gastroesophageal disease (GERD). Esophageal hypervigilance psychological process impacting symptom experience in esophageal disease. However, little known about the presence GERD phenotypes, especially those with acid exposure or index scores. The primary aim was assess differences self‐reported across different presentations. secondary evaluate as predictor severity. Methods We conducted...
Abstract Background Increased esophagogastric junction ( EGJ ) distensibility is thought to contribute gastroesophageal reflux disease GERD ). Using the functional lumen imaging probe FLIP ), we aimed assess esophageal response distension among patients undergoing pH monitoring. Methods 25 (ages 22‐73; 13 females) who underwent ambulatory wireless testing while off proton‐pump inhibitors were evaluated with during sedated upper endoscopy. Esophageal was quantified by total percent acid...
Up to 50% of patients with reflux symptoms do not manifest a satisfactory symptom response proton pump inhibitor (PPI) therapy. Our primary aim in this study was identify factors associated perception among PPI non-responder phenotypes.This prospective observational cohort performed from September 2014 January 2017 at single academic medical center and included non-responders who underwent 24-h impedance-pH monitoring completed questionnaire set measuring patient-reported severity, quality...
Zones of epithelioid cells from single fragments adult human skin and oral mucosa develop on gelatin film. Although the initial appearance these was somewhat slower this substrate, their subsequent migration or growth appeared to be comparable that in plasma clot. Proliferation fibroblast-like observed some cultures film when medium consisted a modified Eagle's basal solution supplemented with 15% calf serum but not 20% 10% 5% serum. Cultural characteristics were similar except more rarely...
// Jerusha Boyineni 1 , Simone T. Sredni 2 3 Naira V. Margaryan 4 Lusine Demirkhanyan Michael Tye Robert Johnson Fernando Gonzalez-Nilo 5 6 Mary J.C. Hendrix 7 Evgeny Pavlov 8 Marcelo B. Soares Eleonora Zakharian * and Sergey Malchenko Department of Cancer Biology & Pharmacology, University Illinois College Medicine, Peoria, Illinois, USA Surgery, Feinberg School Northwestern University, Chicago, Division Pediatric Neurosurgery, Ann H. Lurie Children's Hospital Biochemistry, C. Byrd Health...
The Chicago Classification v3.0 proposed extending the distal contractile integral (DCI) measurement domain to include lower esophageal sphincter (LES) enhance detection of hypercontractility. However, normative and clinical data for this approach are unreported. We aimed describe application an extended DCI in asymptomatic controls patients.High-resolution manometry (HRM) 65 72 patients with normal motility were evaluated retrospectively. Dysphagia chest pain symptoms assessed using brief...
Supragastric belching (SGB) and rumination are behavioral disorders associated with proton pump inhibitor (PPI) non-response can be diagnosed using multichannel intraluminal impedance-pH (MII-pH) post-prandial high-resolution impedance manometry (PPHRIM). This pilot study compared diagnostic yield inter-rater agreement for SGB MII-pH PPHRIM.
Introduction Atherosclerotic coronary artery disease (CAD) is the major cause of mortality in USA. CAD requiring percutaneous intervention (PCI) can have a wide spectrum presentations. We reviewed cost admission and PCI at tertiary care center stratified for different presentation types. Methods performed retrospective study 7,389 patients undergoing angiogram our facility from 2015 to 2017. Patients were selected CathPCI registry. Chart review was done readmission death data. Cost data...