- Chronic Kidney Disease and Diabetes
- Renal and related cancers
- Diet and metabolism studies
- Thyroid Disorders and Treatments
- Dialysis and Renal Disease Management
- Renal Diseases and Glomerulopathies
- Biomedical Ethics and Regulation
- Peroxisome Proliferator-Activated Receptors
- Chronic Disease Management Strategies
- Single-cell and spatial transcriptomics
- Clinical practice guidelines implementation
- Ethics in Clinical Research
- Hepatitis Viruses Studies and Epidemiology
- Digital Imaging for Blood Diseases
- Artificial Intelligence in Healthcare and Education
- Metabolism, Diabetes, and Cancer
- Diabetes Management and Education
- Cardiac Arrhythmias and Treatments
- Cell Image Analysis Techniques
- Healthcare Policy and Management
- Regulation of Appetite and Obesity
- Pharmacology and Obesity Treatment
- Parathyroid Disorders and Treatments
- Lipid metabolism and disorders
- Bone health and osteoporosis research
The University of Texas Southwestern Medical Center
2003-2024
Mashhad University of Medical Sciences
2024
Southwestern Medical Center
2020-2021
The University of Texas Health Science Center at Houston
2000-2001
Lyndon Baines Johnson Hospital
2000
The Kidney Precision Medicine Project (KPMP) is a multisite study designed to improve understanding of CKD attributed diabetes or hypertension and AKI by performing protocol-driven kidney biopsies. Study participants their tissue samples undergo state-of-the-art deep phenotyping using advanced molecular, imaging, data analytical methods. Few patients participate in research design concepts for discovery science. A major goal the KPMP include as equal partners inform clinically relevant...
Background Both bisphosphonates and testosterone are known to improve bone mineral density (BMD) in men with low mass, but whether combination therapy is superior these agents used alone not clear. We compared the changes lumbar spine BMD when mass were treated each agent or as therapy. Methods In a retrospective study, we analyzed serum data from 149 who had been evaluated Endocrinology Clinic at Dallas Veterans Affairs Medical Center, Dallas, Texas. The subjects divided into three cohorts:...
An understanding of the ethical underpinnings human subjects research that involves some risk to participants without anticipated direct clinical benefit-such as kidney biopsy procedure part Kidney Precision Medicine Project (KPMP)-requires a critical examination risks well diverse set countervailing potential benefits participants. This kind deliberation has been foundational development and conduct KPMP. Herein, we use illustrative features this paradigm develop more comprehensive...
Background: Renal cell carcinoma (RCC) is the 9th most common cancer in men and 14th women. To date, there remains considerable uncertainty regarding factors that influence survival of RCC patients. Objectives: This study aimed to determine clinicopathologic characteristics outcomes over a 15-year period northeast Iran. Methods: Data were collected from patient records at Omid Imam Reza Hospitals Radiation Oncology Center 2001 2016. Demographic clinicopathological data extracted records,...
People with diabetes and poor glycemic control (HbA1c ≥9%) have a greater likelihood of complications, increased healthcare utilization, higher total cost care (TCOC). Novel approaches to identify patients at high risk for worsening can improve outcomes contain costs within ACNs. We used XGBoost Decision Trees build validate model predicting increase ≥1.5% over 12 months) using Medicare ACN administrative claims electronic health record data. Eligible members had ≥18 mos. continuous...
This article describes a quality improvement project to reduce the number of patients with diabetes who have poor glycemic control in large tertiary care endocrinology clinic. The used Lean Six Sigma Define-Measure-Analyze-Improve-Control process methodology develop clinic workflow processes for obtaining A1C measurements timely manner facilitate interventions improve control. percentage poorly controlled (A1C >9.0% or missing value past 12 months) significantly improved from 26.4% at baseline 16% (
<h3>Background</h3> Diabetes is a major driver of healthcare cost and utilization in the United States, with one fourth U.S. health care costs spent on caring for people living diabetes approximately 11% American adults having diabetes. <h3>Objectives</h3> To approach from population-based perspective. <h3>Methods</h3> We present framework multidisciplinary care, designed to maximize outcomes available resources (figure 1). The involves population stratification, based complexity risk. At...
Abstract Background: Ventricular arrythmias are a rare, often lethal complication of thyrotoxicosis. We describe patient with uncontrolled hyperthyroidism and pre-ventricular complexes (PVCs) who presented ventricular tachyarrhythmia cardiac arrest was successfully resuscitated. Clinical Case: A 64 year old woman diagnosed thyrotoxicosis secondary to Graves’ disease [TSH &lt; 0.01 (0.40 – 4.5 mcIU/mL) free T4 2.8 (0.8 1.8 ng/dL)] 1 ago in the setting 6 month history weight loss,...
A 54 year old man with Child’s C liver cirrhosis resulting from alcohol abuse presented pleuritic right upper quadrant abdominal pain. He did not have ascites or any history of gastrointestinal bleeding. On examination, his was palpable 4 cm below the costal margin and lobular non-tender. Abdominal ultrasound revealed a mass in lobe (later proved by biopsy to be hepatoma) as well shunt on Doppler study. Magnetic resonance angiography (fig 1) (S) between portal vein (PV) hepatic (HV) which is...