Background Due to the outbreak of coronavirus disease 2019 (COVID-19), school openings were postponed worldwide as a way stop its spread. Most classes are moving online, and this includes medical classes. The authors present their experience running such online with offline clinical clerkship under pandemic conditions, also data on student satisfaction, academic performance, preference. Methods changed every first-year fourth-year course an format except clerkship, skills training, basic...

Biliary atresia (BA) is the major cause of cholestasis and leading indication for liver transplantation (LT). However, incidence BA in Korea has not been reported. The aim this study was to investigate clinical outcomes Korea. We used Korean universal health insurance database extracted data regarding patients younger than 18 years age admitted between 2011 2015. calculated by dividing number live births. Two hundred forty infants were newly diagnosed with BA. A total 963 followed up 5...

The current COVID-19 pandemic have affected our daily lifestyle, pressed us with fear of infection, and thereby changed life satisfaction mental health. study investigated influencing cascade changes during the among personal attitudes, (dis)satisfaction for medical students, using network-based approaches. This cross-sectional survey used self-reports 454 students June July 2020. Depressive mood, anxiety, intention to drop out school were observed in 11.9, 18.5, 38.3% respectively. Directed...

Since the beginning of 2014, Republic Korea has experienced a resurgence measles cases. Among 220 cases confirmed as during epidemiological weeks 1-20 (December 29, 2013 to May 17, 2014), 10 imported were identified. The predominant genotype was B3, which reflects circulating virus in adjacent countries. Even with verification elimination March 2014 by World Health Organization, recent importation been related international travel. Targeted control measures have implemented addition proper...

Inflammatory bowel disease (IBD) is characterised by dysregulated mucosal immune responses associated with genetic, environmental and microbial factors. Recent therapies targeting key inflammatory mediators such as tumor necrosis factor (TNF)-α emphasise the importance of innate immunity in development IBD. We examined distribution cells lymphoid (ILCs) myeloid intestinal epithelium from children diagnosed IBD murine models colitis induced dextran sulphate sodium (DSS) or an anti-CD40...

An elevated alanine aminotransferase (ALT) level is a surrogate marker of non-alcoholic fatty liver disease (NAFLD), the most common disorder in adolescents. The majority previous NAFLD studies adolescents were performed selected obese populations or had cross-sectional design without time-trend analysis. purpose this study was to estimate prevalence and time trends ALT levels general adolescent population identify factors associated with elevation. We analysed data participants (aged 10–18...

ABSTRACT Objectives: This study aims to develop a new prognostic score based on changes in serial laboratory data from patients with pediatric acute liver failure (PALF). Methods: We retrospectively reviewed 146 PALF at the Seoul National University Children Hospital (SNUCH) and Asan Medical Center (AMC). Daily morning records were obtained for up 7 days after diagnosis of PALF: total bilirubin (TB) (mg/dL), international normalized ratio prothrombin time (INR) enrolment; peak TB, INR,...

An Outbreak of Measles in a University Korea, 2014 has been declared eliminated from the Korea since 2006.In April 2014, measles outbreak occurred at Seoul.A total 85 cases were identified.In order to estimate vaccine effectiveness vaccine, we reviewed vaccination records university students.The two doses containing was 60.0% (95% CI, 38.2-74.1;P < 0.05).Transmission interrupted after introduction outbreak-response immunization.The shows that pockets under-immunity among college students may...

Purpose: Monogenic inflammatory bowel disease (IBD) patients do not respond to conventional therapy and are associated with a higher morbidity.We summarized the clinical characteristics of monogenic IBD compared their outcomes that non-monogenic patients.Methods: We performed retrospective cohort study all children ＜18 years old who were diagnosed between 2005 2016.A total 230 enrolled.Monogenic was defined as presentation age less than 6 confirmation genetic disorder.We subdivided groups...

Vitamin D deficiency is a condition widespread throughout the world. Recent studies have suggested that vitamin was associated with obesity and metabolic syndrome. The purpose of study to examine relationship between nonalcoholic fatty liver disease (NAFLD) in adolescents.The data were obtained from Korean National Health Nutrition Examination Survey 2008-2014. A total 3,878 adolescents included study. defined as 25-hydroxyvitamin concentration <20 ng/mL suspected NAFLD an alanine...

It is critical to develop remedial education for underperforming medical students, but little known about how create an effective remediation program. Deliberate practice (DP) a structured and reflective activity that designed optimize performance. Here we applied the concept of DP improve clinical practices students. We also analyzed effectiveness program.Based on expert performance approach DP, 4-week program included feedback reflection. There were 74 student participants in this from...

Developmental trajectories of clinical skills in training physicians vary among tasks and show interindividual differences. This study examined the predictors medical internship performance residency entrance found subtypes trajectory physicians.

Background:The aim of this study was to compare the long-term efficacy entecavir (ETV) and lamivudine (LAM) therapy in children with chronic hepatitis B (CHB) who had not received nucleoside analogue treatment.Methods: In multicenter, retrospective study, we included pediatric CHB patients younger than 20 years ETV or LAM treatment for at least 12 months no concomitant diseases.All were followed up every 1 3 months.At each visit, underwent clinical evaluation biochemical testing.Results:...

Pancreaticopleural fistula (PPF) a fistulous connection between the pancreas and pleural space due to prolonged chronic pancreatitis (CP). PPF is very rare complication which presents in 0.4% of cases, especially among children. We report case involving 3-year-old boy who presented with effusion caused by PPF, hereditary pancreatitis, was, for first time Korea, successfully managed endoscopic treatment. Chest radiography computed tomography showed massive effusion. Percutaneous catheter...

Seoul National University College of Medicine operates a faculty development program for clinical teachers at multiple affiliated teaching hospitals. In 2020, the was moved online due to coronavirus disease 2019. The purpose this study determine whether it is feasible and effective provide programs in terms teachers' participation satisfaction comparison with offline programs.Clinical participated methods 2019 2020. We analyzed rate level. All surveys items were rated on 5-point Likert...

Pediatric Crohn's disease (CD) is directly related to growth and has a high probability of requiring surgical intervention(s); therefore, more active treatment for CD required children. This study investigated the impact biologics on course associated with surgery.This was retrospective cohort involving patients diagnosed at Seoul National University Children's Hospital (Seoul, Korea) between January 2006 October 2017. The aim determine characteristics pediatric whether affected course.Among...

Longitudinal integrated clerkships (LICs) have been adopted by medical schools to overcome the limitations of traditional block clerkship rotations and promote continuity care. In 2018, Seoul National University College Medicine introduced a patient-centered LIC program as part new curriculum in parallel with rotation clerkships. The purpose this study was present investigate its educational effects.In 2018 2019, total 298 third-year students participated program. We divided into groups...

Vitamin D deficiency is common in Crohn disease (CD). The aim of the study was to examine prevalence vitamin and evaluate association between status growth outcome Korean pediatric CD patients.In this retrospective study, 17 children younger than 18 years old diagnosed with were enrolled their serum 25-hydroxy (25[OH]D) checked 2011 2015. We categorized patients into two groups, Group 1 2. included 25(OH)D levels below 10 ng/mL, 2 for a ng/mL 30 ng/mL. z-scores height (Htz), weight (Wtz),...

Giant cell hepatitis with autoimmune hemolytic anemia (AHA) is a rare disease of infancy characterized by the presence both Coombs-positive and progressive liver giant transformation hepatocytes. Here, we report case involving seven-month-old male infant who presented AHA followed cholestatic hepatitis. The clinical features included jaundice, pallor, red urine. Physical examination showed generalized icterus splenomegaly. laboratory findings suggested warm-type Liver biopsy revealed...

The Objective Structured Clinical Examination (OSCE) is a cornerstone of medical education that uses structured approach to assess clinical skills and competency. A well-designed checklist essential enhance the validity OSCE exams. This study aimed determine whether clinically discriminatory (CDC) improves compared with an assessment using thoroughness (TC), particular focus on reasoning.

Patients with lysosomal acid lipase (LAL) deficiency and glycogen storage disease (GSD) demonstrated hepatomegaly dyslipidemia. In our case, a 6-year-old boy presented hepatosplenomegaly. At 3 years of age, GSD had been diagnosed by liver biopsy at another hospital. He showed elevated serum enzymes Liver revealed diffuse microvesicular fatty changes in hepatocytes, septal fibrosis foamy macrophages. Ultrastructural examination numerous lysosomes that contained lipid material intracytoplasmic...

Purpose: Longitudinal integrated clerkships (LICs) have been introduced in medical schools, as learning relationships with clinical faculty or peers are important components of education. The purpose this study was to investigate the characteristics student-faculty and student-student interactions LIC identify other factors related whether students understood acquired program’s main outcomes.Methods: conducted among 149 third-year who participated 2019. We divided into groups eight. These...