A5039944418- Systemic Sclerosis and Related Diseases
- Inflammatory Myopathies and Dermatomyositis
- Spondyloarthritis Studies and Treatments
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Gout, Hyperuricemia, Uric Acid
- Autoimmune Bullous Skin Diseases
- Dermatologic Treatments and Research
- Rheumatoid Arthritis Research and Therapies
- Urticaria and Related Conditions
- Systemic Lupus Erythematosus Research
- Cancer Immunotherapy and Biomarkers
- Eosinophilic Disorders and Syndromes
- Mast cells and histamine
- Psoriasis: Treatment and Pathogenesis
- Vasculitis and related conditions
- Dermatological and Skeletal Disorders
- Cancer Diagnosis and Treatment
- Autoimmune and Inflammatory Disorders Research
- Health Systems, Economic Evaluations, Quality of Life
- Inflammasome and immune disorders
- Colorectal Cancer Treatments and Studies
- Bone Metabolism and Diseases
- Bone and Joint Diseases
- Wnt/β-catenin signaling in development and cancer
- Sarcoidosis and Beryllium Toxicity Research
University of Patras
2016-2025
General University Hospital of Patras
2013-2023
General Hospital Asklepieio Voulas
2022
Laiko General Hospital of Athens
2019
National and Kapodistrian University of Athens
2019
Aristotle University of Thessaloniki
2019
University of Glasgow
2019
University of Thessaly
2018
University Hospital of Larissa
2017-2018
Center for Rheumatology
2013-2018
To assess the efficacy of rituximab (RTX) in SSc.Fourteen patients with SSc were evaluated. Eight randomized to receive two cycles RTX at baseline and 24 weeks [each cycle consisted four weekly infusions (375 mg/m(2))] addition standard treatment, whereas six (control group) received treatment alone. Lung involvement was assessed by pulmonary function tests (PFTs) chest high-resolution CT (HRCT). Skin both clinically histologically.There a significant increase forced vital capacity (FVC)...
Dkk-1 is an inhibitory molecule that regulates the Wnt pathway, which controls osteoblastogenesis. This study was undertaken to explore potential role of in ankylosing spondylitis (AS), a prototypical bone-forming disease.Serum levels were measured 45 patients with AS, rheumatoid arthritis (RA), 15 psoriatic (PsA), and 50 healthy subjects by sandwich enzyme-linked immunosorbent assay (ELISA). A functional ELISA used assess binding its receptor (low-density lipoprotein receptor-related...
Background Accurate diagnosis of cardiovascular involvement in systemic lupus erythematosus (SLE) remains challenging, due to limitations echocardiography. We hypothesized that magnetic resonance can detect cardiac lesions missed by echocardiography SLE patients with atypical symptoms. Aim To use symptoms and investigate the possibility silent heart disease, Patients/methods From 2005 2015, 80 symptoms/signs (fatigue, mild shortness breath, early repolarization sinus tachycardia) aged 37 ± 6...
Data on the safety and efficacy of immune checkpoint inhibitors (ICI) in patients with concurrent autoimmune diseases (AID) are limited.We performed a retrospective multicenter review medical records cancer underlying AID who received ICI. The primary endpoint was progression-free survival (PFS).Among 123 pre-existing ICI, majority had been diagnosed non-small cell lung (NSCLC, 68.3%) melanoma (14.6%). Most rheumatologic (43.9%), or an endocrine disorder (21.1%). Overall, 74 (60.2%)...
Abstract Objective To present the clinical and imaging characteristics of patients with Axial Psoriatic Arthritis (PsA) to identify possible subtypes. Methods Data were retrieved from Greek-multicentre PsA study. (axPsA) was defined as (CASPAR criteria) accompanied by inflammatory back pain (present or ever) positive findings sacroiliac joints and/or spine (MRI: active inflammation spine; X-rays: 1984 New York-criteria for radiographic sacroiliitis presence syndesmophytes in spine)....
The present study aimed to evaluate the prevalence and associations of renal dysfunction in patients with rheumatoid arthritis (RA). It specifically addressed hypotheses that these may associate presence insulin resistance, dyslipidaemia, uric acid levels and/or current systemic inflammation.Renal function was assessed by estimated glomerular filtration rate (GFR) using modification diet disease equation 400 consecutive RA for this cross-sectional, single-centre study. Risk factors were...
Several aquaporins (AQPs) are present in the salivary glands, likely contributing to their secretions. AQP dysfunction may contribute gland SS. Antibodies AQP4 and AQP1 detected neuromyelitis optica believed play a pathogenic role. We aimed search for antibodies several AQPs sera from SS patients an effort shed light on mechanisms of SS.We searched six 34 without neurological findings using ELISAs with synthetic peptides corresponding three extracellular domains each AQP, radioimmunoassays...
Comorbidities are common in chronic systemic connective tissue diseases and associated with adverse outcomes, increased morbidity mortality. Although the prevalence of comorbidities has been well-studied isolated diseases, comparative studies between different autoimmune limited. In this study, we compared patients sclerosis (SSc) rheumatoid arthritis (RA). Between 2016 2017, 408 consecutive SSc, aged 59 ± 13 years (87% women), were matched 1:1 for age gender RA; mean disease duration was 10...