A5082715619- Rheumatoid Arthritis Research and Therapies
- VLSI and Analog Circuit Testing
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Monoclonal and Polyclonal Antibodies Research
- Chronic Lymphocytic Leukemia Research
- Systemic Sclerosis and Related Diseases
- Autoimmune and Inflammatory Disorders Research
- Hepatitis C virus research
- Systemic Lupus Erythematosus Research
- 3D IC and TSV technologies
- Interconnection Networks and Systems
- Integrated Circuits and Semiconductor Failure Analysis
- Inflammatory Myopathies and Dermatomyositis
- Cardiac, Anesthesia and Surgical Outcomes
- Ocular Surface and Contact Lens
- COVID-19 Clinical Research Studies
- Salivary Gland Disorders and Functions
- SARS-CoV-2 and COVID-19 Research
- Sarcoidosis and Beryllium Toxicity Research
- Anesthesia and Pain Management
- Toxin Mechanisms and Immunotoxins
- Psoriasis: Treatment and Pathogenesis
- Spondyloarthritis Studies and Treatments
- Case Reports on Hematomas
- Gout, Hyperuricemia, Uric Acid
Agios Andreas Hospital
2007-2023
St. Josef-Hospital
2023
Witten/Herdecke University
2023
University of Crete
2022
University of Ioannina
2000-2019
401 General Military Hospital of Athens
2018
National and Kapodistrian University of Athens
2018
General University Hospital of Patras
2018
Technological Educational Institute of Epirus
2015
University of Patras
2006-2013
Τo report outcomes of breakthrough COVID-19 in comparison with unvaccinated patients systemic rheumatic diseases (SRDs).Patients SRD (vaccinated and unvaccinated) were included by their rheumatologists a registry operated the Greek Rheumatology Society voluntarily basis. Type, date doses SARS-CoV-2 vaccines recorded, demographics, type SRD, concurrent treatment, comorbidities (hospitalisation, need for oxygen supplementation death) compared between vaccinated patients.Between 1 March 2020 31...
The reciprocal relationship between systemic lupus erythematosus (SLE) and pregnancy was investigated in a controlled study.The outcome of 47 pregnant SLE patients with 59 pregnancies compared that 57 healthy control women pregnancies. results were also those non-pregnant patients.All but one remission at the onset being treated low doses prednisone (< or = 10 mg/day, 26 patients), hydroxychloroquine (200 eight patients) azathioprine (100 patient). Sixty-one per cent delivered term 5% had...
Abstract Introduction This study aimed to determine whether the introduction of anti-SARS-CoV-2 vaccines and dominance omicron variant had a significant impact on outcome COVID-19 in patients with systemic autoimmune rheumatic diseases (SAIRDs). Methods Using data entered Greek Rheumatology Society registry, we investigated incidence hospitalization death due COVID-19, during successive periods pandemic according prevalent strain (wild-type, Alpha, Delta, Omicron) vaccinated unvaccinated...
Patients with rheumatoid arthritis (RA) are at increased risk for serious infections. Pneumococcal vaccination is among the most important preventive measures, however, vaccine uptake suboptimal. We explored rate and factors associated pneumococcal in a contemporary RA cohort. Multi-center, prospective, cohort study Greece. Patient disease characteristics influenza vaccinations were documented baseline 3 years later. One thousand six hundred ninety-seven patients included 34.5% had already...
We have examined the expression of three members ets family genes, ETS1, ETS2 and ERGB/Fli-1, in lymphocytes from patients with systemic lupus erythematosus two murine autoimmune model systems. The ERGB/Fli-1 gene is expressed at a higher level disease than healthy individuals. In addition, we found that splenic T-cells prone mice infiltrating salivary glands HTLV-I tax transgenic mice. Taken together, these results suggest elevated may be prelude to development diseases.
The ETS1 gene encodes a sequence-specific transcription factor binding to purine-rich DNA sequences (-GGAA-) present in the transcriptional regulatory regions of many cellular and viral promoters/enhancers, including lymphokine genes. is expressed at high levels resting T cells very low after cell activation, suggesting it may suppress expression genes induced during activation. To find out if regulates IL-2 gene, we have ectopically antisense (AS) Jurkat block formation proteins. AS...
Aim of the study : To evaluate current disease characteristics, treatment and comorbidities rheumatoid arthritis (RA) in Greece. Methods Multicenter, cross-sectional with a 9-month recruitment period between 2015 2016. Demographics, were collected via web-based platform. Results: 2.491 RA patients recruited: 96% from tertiary referral centers, 79% females mean age 63.1 years duration 9.9 years. Fifty-two percent factor and/or anti-CCP positive, while 41% had erosive disease. Regarding...
Data regarding the real-life predictors of low disease activity (LDA) in rheumatoid arthritis (RA) patients are limited. Our aim was to evaluate rate and LDA treatment patterns RA.This a multicenter, prospective, RA cohort study where were evaluated two different time points approximately 12 months apart. Statistical analysis performed order identify while disease-modifying anti-rheumatic drug [DMARDs; conventional synthetic (csDMARD) or biologic (bDMARD)] glucocorticoid (GC) use also...
To evaluate the effect of phosphodiesterase 4 inhibitor apremilast in biologic-naïve patients with early peripheral PsA terms disease activity, clinical manifestations, patient-perceived outcomes, as well apremilast's safety profile routine care settings Greece. Non-interventional, multicenter, 52-week prospective cohort study, enrolling active who started after intolerance or inadequate response (within first 12 months treatment) to an initial conventional synthetic (cs)DMARD treatment....
Georgiou, P.; Zotou, A.; Siampalioti, Tagari, Tsiotsi, Filos, K. S. Author Information
<h3>Background</h3> We have previously shown that rituximab (RTX) may favorably affect lung function and skin fibrosis in patients with systemic sclerosis (SSc). <h3>Objectives</h3> To assess long term data on efficacy safety of RTX SSc <h3>Methods</h3> Thirty were recruited from three rheumatology departments. Patients treated at baseline, 6, 12 18 months. Beyond two years, retreatment was decided by the treating physician. Follow-up exist for 30, 16, 13, 6 4 1, 2, 3, 5 7 year time points,...
Through-silicon vias (TSVs) are used as high-speed vertical interconnects between dies in a 3-D system-on-a-chip (SoC). However, their speed cannot be exploited during test application due to inherent limitations of the scan-chains cores, which prevent use high shift frequencies scan-in/out operations. Moreover, area cost, only limited number TSVs can utilized for application. As result, become bottleneck transferring large volume test-data various layers stack, and time testing chip...
The use of multiple voltage levels introduces new challenges for testing Multi-V <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">dd</sub> SoCs. Time-Division-Multiplexing (TDM) tackles many these and offers very effective test-schedules. However, the effectiveness TDM minimizing test time depends on Test-Access-Mechanism (TAM) in SoC. Single-V TAM optimization techniques consider neither highly constrained environment multi-V SoCs nor benefits...
Through-silicon vias (TSVs) are used as high-speed interconnects between dies in a 3D System-on-Chip (SoC). However, their speed cannot be utilized during test application due to inherent limitations of the scan chains cores, which prevent use high shift frequencies. Moreover, area cost, only limited number TSVs can for application. As result, time needed transferring data cores multiple considerable. We propose an efficient test-access mechanism (TAM) architecture, exploits minimize testing...