A5019208657- Gut microbiota and health
- Probiotics and Fermented Foods
- CO2 Sequestration and Geologic Interactions
- Animal Nutrition and Physiology
- Diet and metabolism studies
- Food composition and properties
- Hydrocarbon exploration and reservoir analysis
- Drilling and Well Engineering
- Animal Virus Infections Studies
- Carbon Dioxide Capture Technologies
- Concrete and Cement Materials Research
- Clostridium difficile and Clostridium perfringens research
- Gastrointestinal motility and disorders
- Microbial Metabolites in Food Biotechnology
- Geological formations and processes
- Tunneling and Rock Mechanics
- Nitric Oxide and Endothelin Effects
- Food Chemistry and Fat Analysis
- Antioxidant Activity and Oxidative Stress
- Geological and Geochemical Analysis
- Aquaculture disease management and microbiota
- Immune responses and vaccinations
- Gas Dynamics and Kinetic Theory
- Phytochemicals and Antioxidant Activities
- Fatty Acid Research and Health
Netherlands Organisation for Applied Scientific Research
2013-2019
Wageningen University & Research
2003-2004
Schothorst Feed Research
2002
Institute of Animal Sciences
2002
1. The aim of the experiments was to evaluate whether selected probiotic lactobacillus strains have different immunomodulating effects in layer- and meat-type strain chickens. 2. Humoral cellular specific non-specific immune responses were studied by on proliferation, entry survival Salmonella bacteria gut spleen leukocytes, immunoglobulin isotypes titres. 3. two feeding regimes (short continuous feeding) doses for administration lactobacilli studied. 4. that evaluated showed modulating...
The vasorelaxing properties of chocolate and wine might relate to the presence phenolic compounds. One potential mechanisms involved is stimulation endothelial nitric oxide (NO) production, as NO a major regulator vasodilatation. This study aimed develop an in vitro assay using hybrid human cell line EA.hy926 rapidly screen compounds for their NO-stimulating potential. was optimized, selection 33 phenolics, namely, procyanidins, monomeric flavan-3-ols, flavonols, flavone, flavanone,...
Abstract Background Antibiotic associated diarrhea and Clostridium difficile infection are frequent complications of broad spectrum antibiotic therapy. Probiotic bacteria used as therapeutic preventive agents in these disorders, but the exact functional mechanisms mode action poorly understood. The effects clindamycin probiotic mixture VSL#3 (containing 8 bacterial strains Streptococcus thermophilus , Bifidobacterium breve longum infantis Lactobacillus acidophilus plantarum paracasei...
Aim of this study was to investigate the digestion transglutaminase cross-linked caseinate (XLC) versus native (NC) in solution and cheese spread under digestive conditions for adults children mimicked a gastrointestinal model. Samples were collected gel electrophoresis nitrogen analysis. The results showed no relevant differences between XLC NC total α-amino digested fraction adult child conditions. However, rate depending on food matrix. Gel gastric breakdown without formation pepsin...
The bioaccessibility of eicosapentaenoic acid (EPA) in the forms monoacylglycerol (EPA-MAG), triacylglycerol (EPA-TAG), and phospholipid (EPA-PL) during gastrointestinal passage was compared this study using a dynamic model (TIM system). TIM system simulated average upper tract conditions healthy human adults after intake meal (fed state conditions). In study, three EPA-rich oils were separately homogenized with full fat milk to obtain oil-in-water emulsions. Plain yogurt added into mixture...
Oral administration of immunoprobiotic bacteria may support animal health. Species specificity such microorganisms requires appropriate selection. An in vitro assay for the selection lactic acid was developed chicken. The allowed testing large numbers individual strains. Immune stimulation correlated well with vivo situation two experiments and no false negative results occurred. Therefore this is an tool immunomodulating properties
Abstract Samples from Rupel Clay across the Netherlands were analysed for assessment of its heterogeneity in geochemistry and mineralogy. X-ray fluorescence (XRF) bulk clay fraction diffraction (XRD) analyses 152 samples 17 different cores are presented statistically interpreted. The results show a wide variation quartz, feldspar, mineral carbonate content between samples. Factor analysis showed that main variance can be explained by quartz concentration, pyrite plus organic matter. In south...
In the current intensive live stock industry gut flora can be disturbed as aresult of several stressors that affect intestinal tract. New food safety regulations demand to replace antimicrobial additives in poultry feed and still produce healthy poultry. Probiotic micro-organisms like lactic acid bacteria administered with may contribute a strategy comply these demands.Lactobacilli have been shown stimulate immunity, increase colonisation resistance competitive exclusion. This review...
In developing an oral bait BCG vaccine against tuberculosis in badgers we wanted to understand the conditions of gastrointestinal tract and their impact on viability. Conditions mimicking stomach small-intestine caused substantial reduction We performed vivo experiments using a telemetric pH monitoring system used data parameterise dynamic vitro (TIM-1) small intestine. Some died compartment through duodenum jejunum compartments. survival was greatest when absent but by time reached jejunum,...
Currently, there is a constant need to find microbial products for maintaining or even improving host microbiota balance that could be targeted selected consumer group. Blood group secretor status, determining the ABO used stratify group.We have applied validated upper intestinal tract model (TIM-1) and culturing methods screen potential probiotic bacteria from faeces of blood non-secretor individuals.Faecal samples healthy volunteers were pooled age- sex-matched pools. Faecal pools run...
Abstract not provided to SSRN.
Non-isothermal reactive transport modelling is carried out using TOUGHREACT for simulating the near-well behaviour of CO2 injection into compartment two P18 gas field. A representative model was built that contains three geological deposits with va
Many uncertainties exist in geochemical modeling. Mineral reactive surface area is one of the uncertain parameters. QEMSCAN analyses are performed on sandstone samples from a Dutch CO2 natural analogue to determine areas. Geochemical modeling using areas and which conventionally used The model predicts that result higher reaction rates faster equilibration sandstones with CO2. fact reactions predicted occur has been contact for geological times suggests reservoir mineralogy not yet...
One of the challenges in geological CO2 storage still remaining is degradation wellbore cement by acid brine. Laboratory experiments are performed on cement, obtained from an actual well Poland, at high pressure and temperature surplus CO2-sa
Large scale implementation of CO2 storage can significantly reduce emission greenhouse gasses into the atmosphere. However, safe and long-term containment in reservoirs must be ensured. Wellbores subsurface present possible leakage pathways for to surface hence wellbore cement reactivity is major concern. Previous experimental studies often use high brine ratios which may lead overestimations rate alteration. We aim study under more realistic conditions. Limited used represent a environment...