- Advanced Radiotherapy Techniques
- MRI in cancer diagnosis
- Radiation Therapy and Dosimetry
- Radiomics and Machine Learning in Medical Imaging
- Radiation Dose and Imaging
- Prostate Cancer Diagnosis and Treatment
- Head and Neck Cancer Studies
- Medical Image Segmentation Techniques
- Medical Imaging Techniques and Applications
- Advanced X-ray and CT Imaging
- Quality and Safety in Healthcare
- Lung Cancer Diagnosis and Treatment
- Radiopharmaceutical Chemistry and Applications
- Radiation Effects and Dosimetry
- Health Systems, Economic Evaluations, Quality of Life
- Radiation Detection and Scintillator Technologies
- Breast Cancer Treatment Studies
- Prostate Cancer Treatment and Research
- Advanced MRI Techniques and Applications
- Lanthanide and Transition Metal Complexes
University of Maryland, Baltimore
2015-2025
University of Maryland Medical Center
2017
University of Minnesota
2014-2016
Resonance Research (United States)
2016
University of Oklahoma
2010
University of Oklahoma Health Sciences Center
2009
Purpose To develop multiparametric magnetic resonance (MR) imaging models to generate a quantitative, user-independent, voxel-wise composite biomarker score (CBS) for detection of prostate cancer by using coregistered correlative histopathologic results, and compare performance CBS-based with that single quantitative MR parameters. Materials Methods Institutional review board approval informed consent were obtained. Patients diagnosis underwent before surgery treatment. All voxels in the...
Abstract Purpose This study evaluates the impact of a two-year Diversity, Equity, and Inclusion (DEI) intervention program within radiation oncology department. We analyzed employee perceptions inclusivity, bias, training, career development, recognizing challenges assessing DEI initiatives in an evolving sociopolitical context. Methods A voluntary survey was distributed 2021 2023. The assessed four domains: Inclusivity, Department Bias, Training/Education, Career Development. Responses were...
Purpose To present a novel registration approach called LATIS (Local Affine Transformation guided by Internal Structures) for coregistering post prostatectomy pseudo ‐whole mount (PWM) pathological sections with in vivo MRI (magnetic resonance imaging) images. Materials and Methods Thirty‐five patients biopsy‐proven prostate cancer were imaged at 3T an endorectal coil. Excised specimens underwent quarter step‐section pathologic processing, digitization, annotation, assembly into PWM....
This paper describes an LED-based optically stimulated luminescence (OSL) system for dose profile measurements using OSL detector strips and investigates its performance in x-ray computed tomography (CT) dosimetry. To compensate the energy response of Al2O3:C detectors, which have effective atomic number 11.28, field-specific correction factors were determined two methods: (a) comparing profiles with ionization chamber point (0.3 cm3 chamber) (b) integrated over a 100 mm length long pencil...
In vitro T 1 and 2 * relaxivities ( r ) of Gd‐DTPA (GaD) in oxygenated human venous blood (OVB) aqueous solution (AS) at 3 7 were calculated. GaD concentrations ([GaD]) OVB AS prepared the range 0‐5 mM. All measurements acquired 37 ± °C. At both T, a linear relationship was observed between [GaD] R OVB. decreased by 7.5% p = 0.045) while there negligible change With respect to , with only AS, more complex OVB; quadratic below above mM field strengths. There significant increase over 4‐fold...
Abstract Purpose This study aims to illustrate how a script‐based automated tool can efficiently verify documentation for LDR prostate brachytherapy. Methods and Materials: An in‐house Python‐scripts‐based was developed automatically the specific checklists, aligned with our institutional practice guidelines seed implants (PSI). The scripts, compatible radiation oncology information system, could be executed an optional web‐based middleware access evaluate Aria documents. Optimized based on...
Well-designed routine multileaf collimator (MLC) quality assurance (QA) is important to assure external-beam radiation treatment delivery accuracy. This study evaluates the clinical necessity of a comprehensive weekly (C-Weekly) MLC QA program compared American Association Physics in Medicinerecommended picket fence test (PF-Weekly), based on our seven-year experience with QA.The C-Weekly used this includes 5 tests analyze: (1) absolute leaf position; (2) interdigitation (3) positions at...
Purpose: To quantify the factors leading to thermoplastic mask bolus‐associated‐increased skin dose in head and neck IMRT/VMAT using EBT2 film. Methods: film placed beneath a dual layer 3‐point ORFIT head, shoulder was used test effect of thickness, beam modulation, air gap, obliquity on bolus effect. Mask thickness varied based distribution 1.6mm Orfilight top 2 mm Efficast layer. Beam modulation by irradiating with an open field (no modulation) step shoot (beam modulation). Air gap between...
Purpose: Appropriate MLC QA is important to assure treatment accuracy. In addition the TG-142 recommended picket fence test, our institution performs four tests on a weekly basis. The purpose of this study was evaluate clinical necessity program after two-year run. Methods: Our Weekly tests: 1) positioning; 2) Interdigitation for testing hard motion; 3) Picket at static gantry angle; 4) Leaf-end leakage and 5) dose match between VMAT plan same with static-gantry-sliding window. For study,...
Purpose: Calculation‐based patient‐specific IMRT/VMAT QA, as a DICOM‐RT‐based plan verification system, has been commissioned and is currently being used at our institution. We report investigation of failures/warnings out more than 1,000 plans verified over an 18‐month period. Methods: Seven patients with QA from calculation‐based were selected. Dose to 95% PTV volume (D95%) mean dose difference greater 3%, global gamma passing rate less 95%, organ risk (OAR) larger 5% set the...
Purpose: It is important to estimate dose pacemaker (PM)/Implantable Cardioverter Defibrillator (ICD) before undertaking Accelerated Partial Breast Treatment using High Dose Rate (HDR) brachytherapy. Kim et al. have reported HDR PM/ICD a single‐source balloon applicator. To the authors knowledge, there so far not been any published dosimetry literature for Strut Adjusted Volume Implant (SAVI, Cianna Medical, Aliso Viejo, CA). This study aims fill this gap by generating look up table (LUT)...