A5028414176- Viral gastroenteritis research and epidemiology
- Respiratory viral infections research
- Tuberculosis Research and Epidemiology
- Mycobacterium research and diagnosis
- Mosquito-borne diseases and control
- Viral Infections and Immunology Research
- COVID-19 Impact on Reproduction
- Virus-based gene therapy research
- SARS-CoV-2 and COVID-19 Research
- Diagnosis and treatment of tuberculosis
- Global Maternal and Child Health
- Trypanosoma species research and implications
- COVID-19 Clinical Research Studies
- Breastfeeding Practices and Influences
- Pediatric health and respiratory diseases
- Animal Disease Management and Epidemiology
- Tracheal and airway disorders
- Endoplasmic Reticulum Stress and Disease
- Plant Virus Research Studies
- Innovation and Socioeconomic Development
- Public Health and Social Inequalities
- Inflammatory Biomarkers in Disease Prognosis
- Sarcoidosis and Beryllium Toxicity Research
- PI3K/AKT/mTOR signaling in cancer
- Genomics, phytochemicals, and oxidative stress
Universidad Veracruzana
2015-2025
Institut Pasteur de Montevideo
2025
Instituto de Oncología y Radiobiología
2018
Instituto de Salud Pública de Navarra
2015
Centro de Ingeniería Genética y Biotecnología
2007
Early during the infection process, rotavirus causes shutoff of cell protein synthesis, with nonstructural viral NSP3 playing a vital role in phenomenon. In this work, we have found that translation initiation factor 2alpha (eIF2alpha) infected cells becomes phosphorylated early after virus and remains state throughout replication cycle, leading to further inhibition synthesis. Under these restrictive conditions, however, proteins some cellular are efficiently translated. The phosphorylation...
ABSTRACT Initiation is the rate-limiting step in protein synthesis and therefore an important target for regulation. For initiation of translation most cellular mRNAs, cap structure at 5′ end bound by factor eukaryotic 4E (eIF4E), while poly(A) tail, 3′ end, recognized poly(A)-binding (PABP). eIF4G a scaffold that brings together eIF4E PABP, causing circularization mRNA thought to be efficient translation. Early infection, rotaviruses take over host machinery, severe shutoff cell synthesis....
Background/Objectives: Zika disease is caused by the virus (ZIKV) and represents a major public health problem because of complications in newborn babies from mothers who were infected during pregnancy. It estimated that 80% pregnant women are asymptomatic, which complicates identification individuals. In this study, we aimed to detect ZIKV asymptomatic effects newborns analyzed. Methods: The presence was evaluated through endpoint reverse transcription-polymerase chain reaction (RT-PCR) 114...
La inmunofluorescencia es una técnica de detección proteínas en célula. Para la se hace tinción con el uso anticuerpos y fluoróforos; para ver tinción, microscopía fluorescencia. En figura 1 realizó proteína celular llamada eIF4AI eIF4AIII, las cuales son citoplásmica, pero tienen patrones distribución diferentes.
SARS-CoV-2 has rapidly generated a pandemic. Vaccines are currently being rolled out to control the viral spread and prevent deaths. Emergency vaccines, using new platforms, have been approved. Their effectiveness, safety immunogenicity in different populations not fully known. This study aimed discover of messenger ribonucleic acid (mRNA) BNT162b2 adenovirus vector Ad5-nCoV vaccines through IgG antibody generation against subunit 1 protein S (S1 IgG) assess side effects vaccines. A total...
The disease Zika is considered as emergent. infection can be acquired through different routes: a bite from the Aedes mosquito, sexual contact, mother to child during pregnancy and by blood transfusion. possibility of transmission human lactation has been considered. great concern for public health because it associated with neonatal postnatal microcephaly, among other birth defects.To review published evidence probable lactation.Electronic databases: Cochrane Central Register Controlled...
Hepatocellular carcinoma (HCC) is a highly lethal liver cancer with late diagnosis; therefore, the identification of new early biomarkers could help reduce mortality. We determine tissue and plasma status five annexins during hepatocarcinogenesis by diethylnitrosamine-induced cirrhosis-HCC. found that Anxa5 was earliest upregulated gene at week 12 after HCC initiation, while Anxa1 Anxa2 were in advanced stages (weeks 18 22). Furthermore, protein level Annexin A1, A2, A5 A10 increased from...
Acute respiratory infections (ARIs) cause illness. Children under five years of age are highly vulnerable to these infections. Viral coinfection or multiple viral infection is a variable that can have significant impact on the evolution diseases.This cross-sectional study was carried out in Mexican children (under age) who had an ARI and were treated by emergency service hospital Guadalajara, Jalisco, Mexico. The etiology, as well presence infections, determined. A structured questionnaire...
Mexico is on the top five countries with highest number of TB cases in America continent, nevertheless, information about genotypes circulating practically unknown. Considering above this study aims to characterize genetic diversity city Veracruz, México.A cross-sectional was conducted among positive smear samples from patients living Veracruz City, were cultured, and first-line drug profiles determined. Genotyping made by spoligotyping MIRU-VNTR 24 loci. Associations lineages, clusters,...
the aim of study was to use a validated questionnaire identify factors associated with development gastric cancer (GC) in Mexican population.the included cases and controls that were paired by sex ± 10 years age at diagnosis. In relation cases, 46 patients confirmed histopathological diagnosis adenocarcinoma-type GC, as reported hospital records, selected, blood bank donors from same controls. The previously Questionnaire Find Factors Associated Gastric Cancer (QUFA-GC©) used collect data....
To assess the knowledge, attitudes, and practices about Zika virus in both students workers at University of Veracruz, an online survey was conducted. The participants were divided into two groups: one according to sex, other whether they or students. Their answers classified rated as low, medium, high. results showed that knowledge prevailing among university population is considered medium 79.4% study population. Most respondents know mosquito spreads (98.8%) clinical characteristics,...
Human rhinovirus (HRV) is a leading cause of acute respiratory infection (ARI) in young children and infants worldwide has high impact on morbidity mortality this population. Initially, HRV was classified into two species: HRV-A HRV-B. Recently, species called HRV-C possibly another species, HRV-D, were identified. In Mexico, there little information about the role as ARI, presence importance such are not known. The aim study to determine clinical characteristics genetic variability Mexican...
Genes related to DNA damage repair in Mycobacterium tuberculosis are critical for survival and genomic diversification. The aim of this study is compare the presence SNPs genes sensitive drug-resistant M. genomes isolated from patients with without type 2 diabetes mellitus (T2DM). We collected 399 L4 several public repositories; 224 belonging hosts T2DM, which 123 (54.9%) had drug (TB) 101 (45.1%) resistance (DR)-TB; 175 individuals 100 (57.1%) TB 75 (42.9%) DR-TB. coding regions 65 was...
Abstract Background Skin-to-skin contact and breastfeeding initiation within the first hour after birth are key recommendations to promote breastfeeding. In Mexico, National Survey of Demographic Dynamics 2018, known by its Spanish acronym ENADID, collected information about practices. The ENADID survey is probabilistic allows results be generalized entire population in Mexico. Methods Information from a public database featuring 26,587 mother-baby pairs was analyzed proportions, means...
Zika virus (ZIKV) infection in pregnancy is associated with birth and developmental alterations infants. In this study, clinical records of 47 infants whose mothers had during or manifestations compatible were reviewed. A description the infants' anomalies was established, a neurodevelopmental assessment performed on 18 infants, using Evaluation Infant Development (EDI for its initialism Spanish) DDST-II (Denver Developmental Screening Test II) tests. From his sample, 74.5% evaluated major...
El contacto piel con y el inicio de la lactancia materna durante primera hora vida se asocia exclusividad duración materna. En México no existen estudios revisados por pares acerca del conocimiento, actitud práctica en madres atendidas servicios salud privados. Estudio transversal descriptivo que recopiló datos usando preguntas validadas. Las refirieron su recién nacido conformaron grupo A, resto B. La puntuación sobre conocimiento clasificó adecuada adecuada. Se incluyeron 143 madres; 46.2%...
Chronic liver disease is closely linked to dietary intake factors, such as high consumption of simple carbohydrates including sucrose. In this study, the influence sucrose on development hepatocellular carcinoma (HCC), most common primary malignancy, was explored. Using hepatocarcinogen diethylnitrosamine (DEN) induce HCC in rat, we co-administered with DEN. The co-administration significantly modified body, and pancreas weight, well as, serum fatty acids triglycerides. DEN caused structural...