- Mosquito-borne diseases and control
- Viral Infections and Vectors
- Trypanosoma species research and implications
- Malaria Research and Control
- Vector-borne infectious diseases
- Viral Infections and Outbreaks Research
- Fire effects on ecosystems
- Research on Leishmaniasis Studies
- COVID-19 Clinical Research Studies
- HIV Research and Treatment
- SARS-CoV-2 and COVID-19 Research
- Parasitic Infections and Diagnostics
- Virology and Viral Diseases
- COVID-19 and Mental Health
- Dengue and Mosquito Control Research
- Insect symbiosis and bacterial influences
- Long-Term Effects of COVID-19
- Public Health and Environmental Issues
- Neuroinflammation and Neurodegeneration Mechanisms
- Health Systems, Economic Evaluations, Quality of Life
- Parasitic infections in humans and animals
- Public Health and Social Inequalities
- COVID-19 and healthcare impacts
- Peripheral Neuropathies and Disorders
- Diagnosis and treatment of tuberculosis
Instituto Nacional de Salud Pública
2011-2024
Hospital Universitario Río Hortega
2013
Universidad Nacional Autónoma de México
1978-2012
Autonomous University of San Luis Potosí
2012
Universidad de Puebla
1997
Instituto Nacional de Neurología y Neurocirugía
1994
Instituto Nacional de Psiquiatría
1988
ABSTRACT The understanding of dengue virus pathogenesis has been hampered by the lack in vitro and vivo models disease. study viral factors involved production severe dengue, hemorrhagic fever (DHF), versus more common (DF), have limited to indirect clinical epidemiologic associations. In an effort identify determinants DHF, we developed a method for comparing type 2 genomes (reverse transcriptase PCR six fragments) directly from patient plasma. Samples comparison were selected two...
Infection with Trypanosoma cruzi decreases the ability of spleen cells from mice to respond either T cell, concanavalin A (Con A), or B lipopolysaccharide (LPS), mitogens. The effect infection on mitogenic response depends elapsed time between day and mitogen presentation. Responses early in are normal, whereas later responses depressed. Spleen late trypanosome-infected inhibit normal Con LPS. cell T. cruzi-infected responsible for this is nonadherent, sensitive treatment anti-mouse thymus...
En esta comunicación especial de la revista Salud Pública México se hace una breve descripción situación nueva patología causada por el nuevo coronavirus a que OMS ha denominado Covid-19. Se mención los casos ocurridos en China continental y resto del mundo. Del mismo modo, enfatiza arduo trabajo gobierno otros países están realizando para contener epidemia. También papel desempeñando otras organizaciones internacionales las acciones prevención control enfermedad.
SUMMARY Individuals belonging to five families, 12 genera, and 19 different species of bats from dengue endemic areas in the Gulf Pacific coasts Mexico were examined by ELISA, RT–PCR, for presence virus (DV) NS1 protein. Nine individuals four seropositive ELISA: three insectivorous, Myotis nigricans (four positives/12 examined), Pteronotus parnellii (3/19), Natalus stramineus (1/4), one frugivorous Artibeus jamaicensis (1/35) (12·86% seroprevalence positive species). DV serotype 2 was...
To increase our understanding of the consequences dengue virus infection during pregnancy, a retrospective analysis was performed on medical records all completed pregnancies (live births and pregnancy losses) at nine public hospitals in Gulf Mexico from January to October 2013. Eighty-two patients developed clinical, laboratory-confirmed infections while pregnant. Of these, 54 (65.9%) were diagnosed with without warning signs, 15 (18.3%) 13 (15.9%) had severe dengue. Five (38.5%)...
Dengue fever (DF) is the most prevalent arthropod-borne viral disease affecting humans. The World Health Organization (WHO) proposed a revised classification in 2009 to enable more effective identification of cases severe dengue (SD). This was designed primarily as clinical tool, but it also enables SD be differentiated into three specific subcategories (severe vascular leakage, bleeding, and organ dysfunction). However, no study has addressed whether this advantage estimating factors...
Trypanosoma cruzi infection in central Mexico has not been fully documented, yet some data suggest its presence. In this work, sera from 211 subjects living the state of Morelos and at risk T. due to their contact with vector were analyzed for presence antibodies a total antigen extract Mexican isolate cruzi. A seropositivity 20% was demonstrated by both an enzyme-linked immunosorbent assay Western blotting. Furthermore, parasites isolated five seropositive individuals, these genetically...
Abstract Background Aedes aegypti and albopictus are the main mosquito species responsible for dengue virus ( DENV ) transmission to humans in tropical subtropical regions of world. The role vertical epidemiology maintenance this arbovirus nature during interepidemic periods remain poorly understood, could sustain existence reservoirs within populations. Methods Between April 2011 October 2012, we monitored Ae. 9 cities 4 Mexican states. eggs were collected ovitraps, then adults reared under...
OBJETIVO: Documentar las características clínicas y epidemiológicas de los pacientes con dengue atendidos en un hospital Culiacán, Sinaloa, México. MÉTODOS: Estudio transversal, observacional analítico realizado el Hospital General Dr. Bernardo J. Gastélum Culiacán entre 1 octubre 2 diciembre 2003. Se evaluó la asociación variables independientes (las pacientes) variable dependiente (diagnóstico confirmado hemorrágico) mediante análisis regresión simple. Las que mostraron una relación...
Influenza viruses display a high mutation rate and complex evolutionary patterns. Next-generation sequencing (NGS) has been widely used for qualitative semi-quantitative assessment of genetic diversity in biological samples. The "deep sequencing" approach, enabled by the enormous throughput current NGS platforms, allows identification rare viral variants targeted regions, but is usually limited to small number samples.We designed proof-of-principle study test whether redistributing from...
R5-tropic viruses are associated with HIV-1 transmission and predominate during the early stages of infection. X4-tropic populations have been detected in ~50% patients late-stage disease infected subtype B viruses. In this study, we compared frequency X4 tropism individuals CRF14_BG viruses, which a V3 loop B, control group viruses.Sixty-three (n = 31) or 32) were studied. Similar proportions newly diagnosed chronically included groups. sequences obtained coreceptor was predicted using...
Establishing a robust One Health (OH) governance is essential for ensuring effective coordination and collaboration among human, animal, environmental health sectors to prevent address complex challenges like zoonoses or antimicrobial resistance. This study conducted mixed-methods scan assess what extent Mexico displays OH identify opportunities improvement. Through documentary analysis, the mapped national-level elements: infrastructure, multi-level regulations, leadership,...
Abstract Cultures of mouse brain cells containing a high proportion either neurons or astrocytes were inoculated with various strains dengue virus. At analysis by double immunofluorescence, all virus studied tropic for neurons. In no case the infected. Only ∼10% infected, suggesting that may enter cell through membrane receptor present only in subgroup © 1994 Wiley‐Liss, Inc.
OBJETIVO: Determinar la prevalencia de infección por el virus del Nilo Occidental (VNO) en animales, mosquitos y personal que labora dos zoológicos estado Tabasco, México. MATERIAL Y MÉTODOS: Con utilización ELISA bloqueo se detectaron anticuerpos sueros animales: buscó un fragmento genoma VNO RT-PCR suero empleados mosquitos. RESULTADOS: En zoológico "La Venta" encontró una seroprevalencia 25.67% (19/74) aves 85.71% (6/7) reptiles. "Yum-Ká", 31.25% (50/160) las 34.48% (16/29,) los...