A5066693643- Rabies epidemiology and control
- Viral Infections and Vectors
- Microbial infections and disease research
- Virology and Viral Diseases
- Animal Disease Management and Epidemiology
- Poxvirus research and outbreaks
- Animal Virus Infections Studies
- Herpesvirus Infections and Treatments
- Mosquito-borne diseases and control
- Viral Infections and Outbreaks Research
- Bat Biology and Ecology Studies
- Yersinia bacterium, plague, ectoparasites research
- Virus-based gene therapy research
- Zoonotic diseases and public health
- Bartonella species infections research
- Hepatitis B Virus Studies
- Streptococcal Infections and Treatments
- Viral gastroenteritis research and epidemiology
- Vector-borne infectious diseases
- Clostridium difficile and Clostridium perfringens research
- Hepatitis Viruses Studies and Epidemiology
- HIV Research and Treatment
- Hepatitis C virus research
- Vector-Borne Animal Diseases
- Phytoestrogen effects and research
Mexican Social Security Institute
2014-2024
Centro Medico Nacional Siglo XXI
2015-2024
World Health Organization
2020
Centers for Disease Control and Prevention
2020
Onderstepoort Veterinary Institute
2020
Canadian Food Inspection Agency
2020
Animal and Plant Health Agency
2020
Food and Agriculture Organization of the United Nations
2020
Friedrich-Loeffler-Institut
2020
All-Russian Research Institute for Animal Health
2020
Hepatitis C virus (HCV) is among the most relevant causes of liver cirrhosis and hepatocellular carcinoma. Research complicated by a lack accessible small animal models. The systematic investigation viruses mammals could guide efforts to establish such models, while providing insight into viral evolutionary biology. We have assembled so-far largest collection small-mammal samples from around world, qualified be screened for bloodborne viruses, including sera organs 4,770 rodents (41...
A new tentative lyssavirus, Lleida bat was found in a bent-winged (Miniopterus schreibersii) Spain. It does not belong to phylogroups I or II, and it seems be more closely related the West Causasian virus, especially Ikoma lyssavirus.
Hepatitis A virus (HAV) is an ancient and ubiquitous human pathogen recovered previously only from primates. The sole species of the genus Hepatovirus, existing in both enveloped nonenveloped forms, with a capsid structure intermediate between that insect viruses mammalian picornaviruses, HAV enigmatic its origins. We conducted targeted search for hepatoviruses 15,987 specimens collected 209 small mammal globally discovered highly diversified bats, rodents, hedgehogs, shrews, which by...
Domestic dogs are responsible for nearly all the »59,000 global human rabies deaths that occur annually. Numerous control measures have been successful at eliminating dog-mediated in upper-income countries, including dog population management, parenteral vaccination programs, access to vaccines, and education programs bite prevention wound treatment. Implementing these techniques resource-poor settings can be challenging; perhaps greatest challenge is maintaining adequate herd immunity...
In South America, dengue is the arbovirus-transmitted disease with highest incidence. Unlike other arboviruses, wild mammals have no confirmed role in cycle of neotropics, although serological studies suggested a possible secondary amplification involving than nonhuman primates. French Guiana, where all four serotypes (DENV-1, DENV-2, DENV-3, DENV-4) are present, endemic outbreak events. To determine whether can be infected by DENV, rodents, marsupials, and bats were captured over several...
To identify the relationship between landscape use and dengue virus (DENV) occurrence in bats, we investigated presence of DENV from anthropogenically changed unaltered landscapes two Biosphere Reserves: Calakmul (Campeche) Montes Azules (Chiapas) southern Mexico. Spleen samples 146 belonging to 16 species, were tested for four serotypes with standard reverse transcriptase polymerase chain reaction (RT-PCR) protocols. Six bats (4.1%) positive DENV-2: (two Glossophaga soricina , one Artibeus...
The hepatitis C virus (HCV) is a major human pathogen. Genetically related viruses in animals suggest zoonotic origin of HCV. closest relative HCV found horses (termed equine hepacivirus [EqHV]). However, low EqHV genetic diversity implies relatively recent acquisition by horses, making derivation from unlikely. To unravel the evolutionary history within equid sister species, we analyzed 829 donkeys and 53 mules sampled nine European, Asian, African, American countries molecular serologic...
Salivary excretion of rabies virus was evaluated in 14 adult vampire bats ( Desmodus rotundus ) intramuscularly injected with a large dose (10 6 MICLD 50 variant CASS88. Saliva samples were obtained from surviving every other day for 30 days, then weekly 2 months, and finally 1 years later. Rabies isolated murine neuroblastoma cells randomly selected cases by PCR. not detected the saliva any 11 animals that succumbed (somewhat early) to challenge, nor control bats. In contrast, early, only...
SUMMARY Individuals belonging to five families, 12 genera, and 19 different species of bats from dengue endemic areas in the Gulf Pacific coasts Mexico were examined by ELISA, RT–PCR, for presence virus (DV) NS1 protein. Nine individuals four seropositive ELISA: three insectivorous, Myotis nigricans (four positives/12 examined), Pteronotus parnellii (3/19), Natalus stramineus (1/4), one frugivorous Artibeus jamaicensis (1/35) (12·86% seroprevalence positive species). DV serotype 2 was...
Over 90% of human deaths from rabies worldwide are caused by dog bites. Mass vaccination, along with the effective control populations, has been used successfully in industrialised countries to this disease. A lower success rate developing is due a number factors, including vaccination campaigns that do not cover sufficient animals or reach all communities, and wide biodiversity increases reservoirs virus. Educational programmes needed, which focus on commitment involved when acquiring...
Blood-feeding arthropods play a major role in the transmission of several flaviviruses, which represent an important problem for human health. Currently, dengue is one most arboviral emerging diseases worldwide. Furthermore, some previous studies have reported presence viral nucleic acids and antibodies against virus (DENV) wild animals. Our knowledge played by wildlife reservoirs sylvatic maintenance DENV remains limited. objective was to screen blood-feeding ectoparasites (bat flies) their...
Although emerging nonviral pathogens remain relatively understudied in bat populations, there is an increasing focus on identifying bat-associated bartonellae around the world. Many novel Bartonella strains have been described from both bats and their arthropod ectoparasites, including mayotimonensis, a zoonotic agent of human endocarditis. This cross-sectional study was designed to describe isolated sampled Mexico evaluate factors potentially associated with infection. A total 238 belonging...
Adult vampire bats (Desmodus rotundus) were vaccinated by intramuscular, scarification, oral, or aerosol routes (n=8 in each group) using a vaccinia-rabies glycoprotein recombinant virus. Sera obtained before and 30 days after vaccination. All animals then challenged intramuscularly with lethal dose of rabies Neutralizing antirabies antibodies measured rapid fluorescent focus inhibition test (RFFIT). Seroconversion was observed the employed, but some orally failed to seroconvert. The highest...
SUMMARY In February 2008, three white-nosed coatis ( Nasua narica ) were found dead in a recreational park Cancun, Mexico. The diagnosis of rabies virus (RABV) infection was confirmed by direct immunofluorescence test. phylogenetic analysis performed with the complete RABV nucleoprotein gene positioned this isolate close to sequence human case reported during 2008 from Oaxaca, Mexico, sharing 93% similarity. turn, these two variants are related another variant rabid Tadarida brasiliensis...
La rabia es la zoonosis con mayor impacto sobre herbívoros domésticos, provocando en América Latina pérdidas económicas de aproximadamente 97 millones dólares anuales. En esta región, el vampiro común (Desmodus rotundus) un reservorio del virus y se considera su principal transmisor al ganado. El objetivo este estudio fue analizar progresión paralítica bovina (RPB) asociación presencia distribución D. rotundus Tamaulipas, México, función factores ambientales (características ecológicas...
To investigate if non-hematophagous bats play a role in outbreaks of rabies and blue eye disease (LPMV), we studied the seroprevalence against both agents several species on sub-tropical Pacific coast state Colima, Mexico. The survey covered predominantly agricultural area (disturbed), an dominated by semideciduous dry forest (undisturbed). A total 151 16 were captured from two areas. Fifty-six (37%) had antirabic antibodies (Ab) while 87 (58%) did not 8 samples (5%) to be discarded because...
Animal microbiomes play an important role in dietary adaptation, yet the extent to which microbiome changes exhibit parallel evolution is unclear. Of particular interest adaptation extreme diets, such as blood, poses special challenges its content of proteins and lack essential nutrients. In this study, we assessed taxonomic signatures (by 16S rRNA amplicon profiling) potential functional (inferred by Phylogenetic Investigation Communities Reconstruction Unobserved States (PICRUSt))...