A5102914319- Viral gastroenteritis research and epidemiology
- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
Fudan University
2021-2024
Huashan Hospital
2024
Wuhan University
2021
Shanghai Medical College of Fudan University
2021
Fifth Hospital In Wuhan
2021
Abstract New threats posed by the emerging circulating variants of SARS-CoV-2 highlight need to find conserved neutralizing epitopes for therapeutic antibodies and efficient vaccine design. Here, we identified a receptor-binding domain (RBD)-binding antibody, XG014, which potently neutralizes β-coronavirus lineage B (β-CoV-B), including SARS-CoV-2, its variants, SARS-CoV bat SARSr-CoV WIV1. Interestingly, antibody family members competing with XG014 binding show reduced levels...
During the COVID-19 pandemic, three different types of inactivated SARS-CoV-2 vaccines, namely BBIBP-CorV, WIBP-CorV and CoronaVac, were manufactured used for vaccination in China. However, as far we know, no comparison their induced serum neutralization has been carried out so far, possibly due to regional difference vaccine distribution, difficulty undertaking a comprehensive evaluation, intention avoid unnecessary bias populations certain type vaccine.