Lauren Griggs

ORCID: 0000-0001-8141-7040
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About
Contact & Profiles
Research Areas
  • Cellular Mechanics and Interactions
  • Biomedical and Engineering Education
  • Engineering Education and Pedagogy
  • Sustainable Building Design and Assessment
  • Muscle activation and electromyography studies
  • Prosthetics and Rehabilitation Robotics
  • Microtubule and mitosis dynamics
  • Engineering Education and Curriculum Development
  • Higher Education Research Studies
  • 3D Printing in Biomedical Research
  • Robot Manipulation and Learning
  • Career Development and Diversity
  • Yersinia bacterium, plague, ectoparasites research
  • Structural Engineering and Vibration Analysis
  • TGF-β signaling in diseases
  • Pharmacological Effects of Natural Compounds
  • E-Learning and Knowledge Management
  • Cancer Cells and Metastasis
  • Vibrio bacteria research studies
  • Healthcare professionals’ stress and burnout
  • Botanical Research and Chemistry
  • Digestive system and related health
  • TiO2 Photocatalysis and Solar Cells
  • Optimism, Hope, and Well-being
  • Construction Project Management and Performance

University of Virginia
2024

UPMC Altoona
2024

American Society For Engineering Education
2024

Virginia Commonwealth University
2016-2024

Pennsylvania State University
2021-2024

University of California, San Francisco
2024

North Carolina State University
2024

University of Calgary
2020

University of North Carolina at Chapel Hill
2016

University of Alabama in Huntsville
2014

Diabetes mellitus is a complex metabolic disorder that associated with an increased risk of breast cancer. Despite this correlation, the interplay between tumor progression and diabetes, particularly regard to stiffening extracellular matrix, still mechanistically unclear. Here, we established murine model where hyperglycemia was induced before development. Using model, in vitro systems, patient samples, show increases growth, matrix stiffness, glycation, epithelial-mesenchymal transition...

10.1126/sciadv.abo1673 article EN cc-by-nc Science Advances 2022-11-16

This paper presents a detailed electrochemical impedance spectroscopy and cyclic voltammetry (CV) investigation into the electrocatalytic activity of ultrafine (i.e., smaller than 2 nm) platinum (Pt) nanoparticles generated on fluorine-doped tin oxide (FTO) surface via room temperature tilted target sputter deposition. In particular, Pt-decorated FTO electrode surfaces were tested as counter candidates for triiodide () reduction in dye-sensitized solar cells (DSSCs). We observed direct...

10.1088/0957-4484/23/48/485405 article EN Nanotechnology 2012-11-09

Abstract Purpose: The purpose of the Sustainable Bridges from Campus to project (NSF IUSE #1525367, known locally as Engineering Ahead) is establish summer bridge programs that serve students at regional campuses Pennsylvania State University. In 2016, residential for incoming were started Abington, Altoona, and Berks campuses. Recruitment focuses on enrolling racially underrepresented domestic (i.e., African American, Hispanic Native Pacific Islander) first-generation in into programs. also...

10.18260/1-2--37793 article EN mit 2020 ASEE Virtual Annual Conference Content Access Proceedings 2024-02-20

Abstract The purpose of this Complete Research paper is to discuss a shift in the programmatic structure six-week engineering summer bridge program, designed support academic and social integration incoming first-year students into Pennsylvania State University community. Along with acclimating their chosen or science-based discipline, program includes structured cultural events that encourage build relationships one another relate in-class activities out-of-class experiences. A primary goal...

10.18260/1-2--41608 article EN 2024-02-06

Implication Statement 
 Acutely traumatic clinical events can exacerbate stress and burnout amongst healthcare providers. The Simulated Training for Resilience in Various Environments (STRIVE) course may provide a useful framework medical educators to teach management skills promote resilience physician trainees. introduces the Big Four+ techniques (goal setting, visualization, self-talk, progressive muscular relaxation, attention control tactical breathing) created by Canadian Armed...

10.36834/cmej.69821 article EN cc-by-nc-nd Canadian Medical Education Journal 2020-12-01

Epithelial to Mesenchymal Transition (EMT) is a dynamic, morphogenetic process characterized by phenotypic shift in epithelial cells towards motile and often invasive mesenchymal phenotype. We have previously demonstrated that EMT associated with an increase assembly of the extracellular matrix protein fibronectin (FN) into insoluble, viscoelastic fibrils. also Transforming Growth Factor-β1 (TGF-β1) localizes FN fibrils, disruption or TGF-β1 localization fibrils attenuates EMT. Previous...

10.3390/ijms24076679 article EN International Journal of Molecular Sciences 2023-04-03

Pre-college summer transition programs are prevalent at colleges and universities around the country generally associated with positive impacts on student retention graduation rates. At Virginia Commonwealth University, a six week hybrid on-campus/online program is offered to incoming science, technology, engineering, mathematics majors from racial ethnic backgrounds underrepresented in those disciplines (i.e., African American, Latino/a, Native American). This work-in-progress investigates...

10.1109/fie.2016.7757527 article EN 2021 IEEE Frontiers in Education Conference (FIE) 2016-10-01

Commercially available robotic prosthetic arms currently use independent joint control. An alternative controller involving only control of the hand in a Cartesian frame rather than controlling each independently is proposed and tested. experimental 4DOF arm was used as platform for testing approach. As opposed to control, requires solution inverse kinematics problem. The developed using extended Jacobian method. two methodologies, were tested on five able-bodied human subjects. Improvement...

10.2174/1874120701408010093 article EN The Open Biomedical Engineering Journal 2014-10-30

Abstract Epithelial cells form continuous sheets of that exist in tensional homeostasis. Homeostasis is maintained through cell-to-cell adhesions distribute tension and balance forces between their underlying matrix. Disruption homeostasis can lead to Epithelial-Mesenchymal Transition (EMT), which a transdifferentiation process epithelial adopt mesenchymal phenotype, where cell-cell adhesion lost individual cell migration acquired. This critical during embryogenesis wound healing, but also...

10.1101/701037 preprint EN cc-by bioRxiv (Cold Spring Harbor Laboratory) 2019-07-12

ABSTRACT The Yersinia enterocolitica Ysa type III secretion system (T3SS) is associated with intracellular survival, and, like other characterized T3SSs, it tightly controlled. Expression of the ysa genes only detected following growth at low temperatures (26°C) and in high concentrations sodium chloride (290 mM) medium. YsrSTR phosphorelay (PR) required for expression likely responds to NaCl. During our investigations into Ysr PR system, we discovered that YE3578 YE3579 are remarkably...

10.1128/jb.00240-16 article EN Journal of Bacteriology 2016-04-05

Abstract The mission of the Virginia Commonwealth University Louis Stokes Alliance for Minority Participation (VCU LSAMP) is to increase retention and graduation rate underrepresented minority students in STEM majors, with aims matriculating this population into graduate programs. VCU LSAMP offers various initiatives throughout school year support academic success its students, including summer transition program (STP), aimed at facilitating high college process majoring disciplines. Similar...

10.18260/1-2--31754 article EN 2024-02-13

Abstract In this GIFTS paper we discuss the Engineering Equity Summit, an annual event representing evolution of extensive collaborative efforts with student leaders to integrate equity into greater engineering community at university. The event, held each April Pennsylvania State University, University Park, was developed bring together students, faculty, staff, alumni, and industry partners promote education, awareness, action on issues inclusion in community. As part 2020-2025 Strategic...

10.18260/1-2--45070 article EN 2024-02-06

Abstract The A. James Clark Scholars Program at Penn State leverages signature strengths of the College Engineering to serve needs talented engineering students with significant financial need. builds upon four thematic pillars: business and entrepreneurship, leadership, social equity global citizenship, community engagement. As part their co-curricular opportunities, engage in a cohort-based experience that fosters positive academic outcomes while develop confidence, deepen peer networks,...

10.18260/1-2--45465 article EN 2024-04-02

The mission of the Virginia Commonwealth University Louis Stokes Alliance for Minority Participation (VCU LSAMP) program is to increase retention and graduation rates students from underrepresented racial ethnic groups in science, technology, engineering, mathematics (STEM) majors those who matriculate into graduate programs. VCU LSAMP offers a hybrid summer transition (HSTP) focused on facilitating high school college two-year four-year process majoring STEM disciplines. goals are 1) build...

10.3389/feduc.2021.674337 article EN cc-by Frontiers in Education 2021-06-29

Commercially available robotic prosthetic arms currently use independent joint control. An alternative controller involving only control of the hand in a Cartesian frame rather than controlling each independently is proposed and tested. experimental 4DOF arm was used as platform for testing approach. As opposed to control, requires solution inverse kinematics problem. The developed using extended Jacobian method. two methodologies, were tested on five able-bodied human subjects. Improvement...

10.2174/1874095201408010093 article EN The Open Biomedical Engineering Journal 2014-10-30
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