A5091403092- Catalytic C–H Functionalization Methods
- Synthesis and Catalytic Reactions
- Catalytic Cross-Coupling Reactions
- Asymmetric Hydrogenation and Catalysis
- Psychosocial Factors Impacting Youth
- Intergenerational Family Dynamics and Caregiving
- Cyclopropane Reaction Mechanisms
- Korean Urban and Social Studies
- Education and Learning Interventions
- Catalytic Alkyne Reactions
- Sulfur-Based Synthesis Techniques
- Synthesis of Indole Derivatives
- Oxidative Organic Chemistry Reactions
- Child Abuse and Trauma
- Radical Photochemical Reactions
- Family Dynamics and Relationships
- Carbon dioxide utilization in catalysis
- Homicide, Infanticide, and Child Abuse
- Child Therapy and Development
- Diverse Approaches in Healthcare and Education Studies
- Health and Well-being Studies
- Diverse Topics in Contemporary Research
- Educational Systems and Policies
- Intimate Partner and Family Violence
- Advanced Synthetic Organic Chemistry
Seoul National University
2016-2023
Kwangshin University
2014-2016
Sungkyunkwan University
2013-2015
Suwon Research Institute
2014
Palladium-catalyzed decarboxylative acylation of highly substituted indolines with α-keto acids via C–H bond activation is described. This protocol provides efficient access to C7-carbonylated indoles known have diverse biological profiles.
Abstract The rhodium‐catalyzed selective cyanation of CH bonds indolines and indoles with N ‐cyano‐ ‐phenyl‐ para ‐methylbenzenesulfonamide is described. This protocol offers a facile access to C‐7 cyanated C‐2 high site selectivity excellent functional group tolerance. magnified image
The ruthenium-catalyzed oxidative allylation of aromatic and α,β-unsaturated carboxamides with allylic carbonates is described. These transformations proceed readily complete linear γ-selectivity substituted carbonates.
The rhodium(III)-catalyzed direct allylation of indolines with allylic carbonates at room temperature is described. These transformations provide the facile and efficient construction C7-allylated indolic scaffold.
Abstract The palladium‐catalyzed oxidative acylation of indolines at the C‐7 position with aldehydes or alcohols via CH bond activation is described. This protocol represents a facile access to 7‐acylated indolines, which can be readily transformed into indoles diverse biological properties. magnified image
A ketone-assisted ruthenium-catalyzed selective amination of xanthones and chromones C–H bonds with sulfonyl azides is described. The reactions proceed efficiently a broad range substrates excellent functional group compatibility. This protocol provides direct access to 1-aminoxanthones, 5-aminochromones, 5-aminoflavonoid derivatives known exhibit potent anticancer activity.
A rhodium(III)-catalyzed oxidative olefination of 1,2-disubstituted arylhydrazines with alkenes via sp2 C–H bond activation followed by an intramolecular aza-Michael reaction is described. This strategy allows the direct and efficient construction highly substituted 2,3-dihydro-1H-indazole scaffolds.
The rhodium-catalyzed oxidative C2-olefination of indoles and pyrroles containing <italic>N</italic>-arylcarboxamide directing groups with a range alkenes subsequent cleavage is described.
The rhodium-catalyzed oxidative alkenylation of<italic>N</italic>-benzyltriflamides with olefins followed by an intramolecular cyclization<italic>via</italic>C–H bond activation is described.
A palladium-catalyzed oxidative coupling of arene C-H bonds with benzylic ethers via bond activation is described. The reaction proceeds efficiently a broad range substrates bearing conventional directing groups excellent functional group compatibility. This protocol potentially provides opportunities to use dibenzyl as new acyl equivalents for catalytic acylation reactions.
A copper-catalyzed oxidative coupling of 2-carbonyl-substituted phenols and 1,3-dicarbonyl compounds with a wide range dibenzyl or dialkyl ethers is described. This protocol provides an efficient preparation phenol esters enol in good yields high chemoselectivity. method represents alternative for classical esterification reactions.
Transition-metal-catalyzed oxidative and decarboxylative acylations of sp2 C-H bonds bearing conventional directing groups with various acyl equivalents, such as aldehydes, alcohols, alkylbezenes, -keto acids, etc. are described. These protocols present an effective promising route to obtain aryl ketones, which found be important precursors for the formation bioactive molecules functional materials. Thus, potentially provide a catalytic alternative overcome limitations classical...
연구목적: 본 연구는 코로나19의 확산에 따른 빈곤가정 아동·청소년의 개인생활, 정서와 가족생활의 변화 양상을 살펴보고, 이러한 일상생활 변화가 행복감에 미치는 영향을 실증 분석을 통해 검증하고자 하였다.방법: 기아대책에서 수집한 자료를 사용하여 11~19세 아동·청소년 415명을 대상으로 기술통계 분석과 위계적 회귀분석을 실시하였다.결과: 첫째, 코로나19 확산 이후 또래관계 불안 및 학업성적 불안이 증가한 경우가 많았다. 약 1/4의 아동·청소년에게 부모의 신체적 위협이 증가하였으며, 성인 없이 아동·청소년만 집에 있는 시간은 감소한 경우보다 둘째, 불안과 경우 행복감이 유의하게 반면, 시간이 행복감은 증가하였다.결론: 아동·청소년이 효과적으로 온라인 수업을 들을 수 있도록, 아동학대나 가정폭력이 발생할 신속하게 신고할 그리고 제도적 사각지대에 놓인 빈곤가정의 돌봄 공백에 대응하기 위하여 구체적이고 실질적인 지원방안을 정책적으로 모색하고 마련해야 할 것이다.
연구목적: 본 연구는 이혼한 모자한부모가족 내 비양육부와의 만남과 연락, 이혼부모 간관계가 청소년 자녀의 향후 면접교섭 의향에 미치는 영향에서 비양육부와 자녀 간 친밀감의매개효과를 검증하였다. 이를 통해 요인을 탐색하고, 아동의 권리보장을 위해 고려할 점을 제안하였다. 방법: 2021년 수도권에 거주하는 11-19세 171명을 대상으로 온라인설문조사를 수집한 자료를 사용하였으며, STATA와 M-plus를 활용하여 기술통계분석, 경로분석과 부트스트랩핑을 실시하였다. 결과: 지난 6개월 동안 청소년이 만난 경우, 그리고 자주 연락했을수록 비양육부에 대한 친밀감은 각각 높았다. 친밀감이 높을수록 청소년의 의향도 증가하였다. 관계가 좋다고 생각할수록 비양육부에게 높았으며, 의향이 부트스트랩핑 검증 결과, 만남 또는 연락이 의향에미치는 영향을 모두 유의하게 매개하였다. 또한 관계도 친밀감을 매개하여 유의한 간접효과를 나타냈다. 결론: 비양육부모는 자녀에게 먼저 전화, 문자와...
This study examined whether child support payments, perceived compensation, cost of rearing, and potential from former spouse, which are all factors related to custodial parent’s motivation allow visitation, affect contact between children non-custodial parents. The types were divided into regular contact, irregular no contact. A comparison single-father single-mother families was conducted see if parents different by gender Using the Living Status Korean Single-Parent Families Survey, this...
This study aims to examine the effects of child neglect from parents on mobile phone dependency adolescents focusing peer attachment and usage by purposes as mediating variables. The participants were 2,002 early drawn 7th waves (2016) KCYPS (Korean Children Youth Panel Survey). Structural equation modeling bootstrapping employed. Results follows. First, teenagers experienced their parents, communication trust decreased while alienation increased significantly. Child significantly reduced...
This study examined the effect of parental achievement-oriented expectation on high school students’ depression and verified mediating peer relations relations. Data were derived from 7th wave (2016) Korean Children Youth Panel Survey (KCYPS), 1,979 students included. Descriptive statistics analysis, correlation multiple regression a Sobel test conducted using STATA. The main results as follows. First, male adolescents perceived higher expectation, lower relations, but than female...
Abstract The efficient and scalable allylation of indolines is performed using an N‐butylcarbamoyl directing group providing the products as inseparable mixture E/Z isomers with (Z)‐isomer being major product.
Abstract This C2‐alkenylation of indoles (I) typically proceeds with high levels regio‐ and stereoselectivity.
Abstract Review: 119 refs.
Abstract This protocol provides an efficient preparation of phenol esters and enol in good yields with high chemoselectivity.