Wen Li

ORCID: 0000-0001-8252-7727
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About
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Research Areas
  • Pulmonary Hypertension Research and Treatments
  • Ferroptosis and cancer prognosis
  • Cognitive Functions and Memory
  • Cancer-related cognitive impairment studies
  • Cancer Immunotherapy and Biomarkers
  • Cardiovascular Function and Risk Factors
  • Inflammasome and immune disorders
  • Endometriosis Research and Treatment
  • Dementia and Cognitive Impairment Research
  • Heart Failure Treatment and Management
  • RNA modifications and cancer
  • Cancer-related molecular mechanisms research
  • Traditional Chinese Medicine Analysis
  • Corneal Surgery and Treatments
  • Corneal surgery and disorders
  • Glioma Diagnosis and Treatment
  • Uterine Myomas and Treatments
  • Renal cell carcinoma treatment
  • Glaucoma and retinal disorders
  • Traditional Chinese Medicine Studies
  • Gynecological conditions and treatments

Sichuan University
2012-2022

Chinese Academy of Medical Sciences & Peking Union Medical College
2022

Second Hospital of Anhui Medical University
2017-2022

Anhui Medical University
2017-2022

Sun Yat-sen University
2021

The First Affiliated Hospital, Sun Yat-sen University
2021

Qingdao University
2021

Qingdao Municipal Hospital
2021

Central South University
2017

West China Hospital of Sichuan University
2012

Abstract In this study, we aimed to investigate the intrinsic hippocampal functional connectivity (FC) network and its relationship with prospective memory in patients breast cancer suffering from chemotherapy-induced cognitive impairment (CICI). Thirty-four before after adjuvant chemotherapy (CB CC, respectively) 31 age- education-matched cognitively normal (CN) women were recruited subjected a task resting-state magnetic resonance imaging scan. Seed-based analysis was used compare FC...

10.1038/srep45135 article EN cc-by Scientific Reports 2017-03-22

The role of pyroptosis, which is also a kind cell-intrinsic death mechanism, in tumorigenesis and cancer progression has been revolutionized. However, the expression pyroptosis-related genes (PYGs) colon (CC) their prognostic value remain unclear. In this study, we comprehensively identified two PYG-mediated molecular subtypes with distinct tumor microenvironment (TME) 1,415 CC samples, were based on 10 PYGs. six-gene signature (pyroptosis score, PY-score) was constructed to quantify...

10.3389/fcell.2021.766503 article EN cc-by Frontiers in Cell and Developmental Biology 2021-11-10

Previous findings indicated that polymorphism in gene catechol-O-methyltransferase (COMT) had been linked to chemotherapy-related cognitive impairment (CRCI). Nevertheless, the motivation of COMT polymorphisms regulating breast cancer survivors with disparate status human epidermal growth factor receptor 2 (HER2) was still vague.The current research aimed evaluate regulation risk by genotype on CRCI HER2.Breast (103 HER2- and 118 HER2+) underwent neuropsychological tests before after...

10.3389/fonc.2022.816923 article EN cc-by Frontiers in Oncology 2022-02-08

Abstract Background: Coronary artery disease (CAD) is the commonest cause of heart failure (HF), whereas pulmonary hypertension (PH) has not been established or reported in this patient population. Therefore, we assessed prevalence, risk factors, and survival CAD-associated HF (CAD-HF) complicated with PH. Methods: Symptomatic CAD-HF patients were continuously enrolled prospective, multicenter registry study. Echocardiography, coronary arteriography, left right catheterization (RHC), other...

10.1097/cm9.0000000000002112 article EN cc-by-nc-nd Chinese Medical Journal 2022-07-27

10.3724/sp.j.1008.2012.00681 article EN Academic Journal of Second Military Medical University 2013-06-06

Background: The tumor microenvironment evidently affects treatment response and clinical outcome. This study aims to construct a microenvironment-based crosstalk between immunotherapy epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) in lung adenocarcinoma. Methods: We used ESTIMATE algorithm calculate stromal immune scores. Differentially expressed genes (DEGs) were extracted based on the comprehensive analysis of score groups EGFR-TKI resistance samples. independent...

10.7150/jca.57008 article EN cc-by-nc Journal of Cancer 2022-01-01

To explore the clinical efficacy of traditional Chinese medicine decoction combined with recombinant human interferon α2b in treatment renal cell carcinoma (RCC).68 RCC patients were divided into control group and (n = 34). The was treated α2b, on basis group. life quality observed. At same time, changes immune function before after compared.After one course treatment, effective rate benefit higher than those Karnofsky score better that In improving function, increasing CD3+ CD4+ reducing...

10.1155/2021/8106974 article EN Evidence-based Complementary and Alternative Medicine 2021-10-25
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