A5046729660- Osteoarthritis Treatment and Mechanisms
- Lower Extremity Biomechanics and Pathologies
- Cancer-related molecular mechanisms research
- Gear and Bearing Dynamics Analysis
- Advanced X-ray and CT Imaging
- Medical Imaging Techniques and Applications
- Digital Radiography and Breast Imaging
- Collagen: Extraction and Characterization
- Proteoglycans and glycosaminoglycans research
Edinburgh Royal Infirmary
2019
Oulu University Hospital
2011-2016
University of Oulu
2011-2015
University of Eastern Finland
2011
To evaluate the sensitivity of quantitative MRI techniques (T1 , T1,Gd T2 continous wave (CW) T1ρ dispersion, adiabatic T2ρ RAFF and inversion-prepared magnetization transfer (MT)) for assessment human articular cartilage with varying degrees natural degeneration.Osteochondral samples (n = 14) were obtained from tibial plateaus patients undergoing total knee replacement. specimens was performed at 9.4T relaxation time maps evaluated in zones. For reference, histology, OARSI grading...
ABSTRACT Several laboratory and rotating frame quantitative MRI parameters were evaluated compared for detection of changes in articular cartilage following selective enzymatic digestion. Bovine osteochondral specimens subjected to 44 h incubation control medium or collagenase chondroitinase ABC induce superficial collagen proteoglycan (glycosaminoglycan) alterations. The samples scanned at 9.4 T 1 , Gd (dGEMRIC), 2 adiabatic ρ continuous‐wave RAFF2 sat relaxation times magnetization...
Adequate reproduction of low contrast image detail is essential for accurate diagnosis in diagnostic radiology. Artinis CDRAD and Leeds Test Object TO20 are commercially available test objects that can be used to this aspect imaging performance digital radiography. Automated analysis software both (CDRAD Analyser AutoPIA (TO20)). This study evaluated compared software, including their sensitivity changes exposure parameters processing. Images the were acquired scatter scatter-free...