A5029326366- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Circular RNAs in diseases
- Cancer-related molecular mechanisms research
- Occupational and environmental lung diseases
- RNA modifications and cancer
- Epigenetics and DNA Methylation
- Birth, Development, and Health
- Vascular Malformations Diagnosis and Treatment
- Pregnancy and preeclampsia studies
- Management of metastatic bone disease
- Prostate Cancer Treatment and Research
- Geoscience and Mining Technology
- Genomics, phytochemicals, and oxidative stress
- Gestational Diabetes Research and Management
- Radiopharmaceutical Chemistry and Applications
- Acute Myeloid Leukemia Research
- Histone Deacetylase Inhibitors Research
- Cancer-related Molecular Pathways
- Teratomas and Epidermoid Cysts
- Medical Imaging and Pathology Studies
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Cancer, Hypoxia, and Metabolism
- PARP inhibition in cancer therapy
- MicroRNA in disease regulation
- Neonatal Respiratory Health Research
Third Affiliated Hospital of Zhengzhou University
2011-2024
Chongqing Medical University
2021
First Affiliated Hospital of Xi'an Jiaotong University
2019-2020
Taixing People's Hospital
2008
Long non-coding RNA musculin antisense 1 (lncRNA MSC-AS1) has been recognized as an oncogene in pancreatic cancer, hepatocellular carcinoma, nasopharyngeal and renal cell carcinoma.However, the functional significance of MSC-AS1 its underlying mechanism gastric cancer (GC) progression remain unclear.In this study, we demonstrated that expression GC tissues was significantly higher than non-tumor tissues.Moreover, elevated level detected cells (MKN-45, AGS, SGC-7901, MGC-803) compared to...
Silicosis is a serious occupational disease characterized by pulmonary chronic inflammation and progressive fibrosis. Epithelial-mesenchymal transition (EMT) of alveolar epithelial cells plays vital role in silicosis. Recent studies discovered variety microRNAs (miRNAs) participating fibrotic diseases. Here, we aimed to explore the function mechanism miRNA let-7d EMT process silica-induced cells. To detect whether its target HMGA2 were involved EMT, established silicosis mouse model found...
Tumor suppressor genes RB1 and TP53 are altered frequently in prostate cancer (PC), whether inactivation promotes radioresistance remains unclear. Herein, we demonstrated that loss enhanced ionizing radiation (IR)-induced DNA damage to inhibit cell proliferation promote cellular senescence through a TP53-dependent pathway LNCaP cells. Furthermore, the stabilization of was regulated by ATM-mediated phosphorylation MDM2 at Ser395. However, RB1/TP53 reversed damage-induced promoted survival....
Objectives To assess the predictive accuracy of three-dimensional (3D) power Doppler combined with two-dimensional (2D) ultrasonography in detecting fetal growth restriction (FGR).
Satellite cells, the muscle stem play a critical role in growth, maintenance, and regeneration. A lot of diseases result from defective function satellite cells. Porcine cells are good model for studying development. Sulforaphane (SFN), natural molecule rich cruciferous vegetables, is potent inducer NF-E2-related factor 2 (Nrf2) signaling also inhibits activity histone deacetylases (HDAC). Our previous study found that SFN epigenetically suppressed transcription myostatin porcine However,...
Objective To explore CT and M RI scan technique in diagnosis of cerebral cavernous angiomas (CA). Meth- ods MRI findings CA 36 cases proved by operation pathology were reviewed. Results The lesion in- tracerebral hemangioma could be located every region the brain, which single was more often mosl lesions had no or slightly edema without space - occupying effect slight hyperdensity mass appeared plain scan, calcification seen 68.7% mass, most them shown enhancement. characteristic features...
Objective To evaluate the feasibility of 153 Sm-EDTMP for multiple bone metastasis.Methods 32 patients with metastases were treated injected into veins,0.4～1.0 mci/kg,of which 7 cases received therapy 2～3 times.Results 53.1%(17/32)was relieved completely,25.0%(8/32)was partially and 9.4%(3/32)was slightly.No effects found in 12.5%(4/32).The overall effective rate was 78.1%.Side that decreasing WBC PLT 15.6%(5/32),which rose to preoperative levels within 6～8 weeks.Conclusion Internal...