A5017253537- 3D Printing in Biomedical Research
- Electrospun Nanofibers in Biomedical Applications
- Tissue Engineering and Regenerative Medicine
- Innovative Microfluidic and Catalytic Techniques Innovation
- Additive Manufacturing and 3D Printing Technologies
- Cardiac Valve Diseases and Treatments
- Cell Image Analysis Techniques
- Cardiac and Coronary Surgery Techniques
- Pickering emulsions and particle stabilization
- Nanocluster Synthesis and Applications
- Enzyme Catalysis and Immobilization
- Quantum Dots Synthesis And Properties
- Photoacoustic and Ultrasonic Imaging
- RNA Interference and Gene Delivery
- Advanced biosensing and bioanalysis techniques
- Polymer Surface Interaction Studies
- Thermoregulation and physiological responses
- Micro and Nano Robotics
- Viral Infectious Diseases and Gene Expression in Insects
- Electrohydrodynamics and Fluid Dynamics
- Algal biology and biofuel production
- Angiogenesis and VEGF in Cancer
- Bone Tissue Engineering Materials
University of Twente
2018-2024
Technical University of Denmark
2017
Compartmentalized Janus microparticles advance many applications ranging from chemical synthesis to consumer electronics. Although these particles can be accurately manufactured using microfluidic droplet generators, the per-nozzle throughputs are relatively low (∼μL/min). Here, we use "in-air microfluidics" combine liquid microjets in midair, thereby enabling orders of magnitude faster production (∼mL/min) as compared chip-based microfluidics. Monodisperse with diameters between 50 and 500...
Cell organelles are subcellular structures entrapping a set of enzymes to achieve specific functionality. The incorporation artificial into cells is novel medical paradigm which might contribute the treatment various cell disorders by replacing malfunctioning organelles. In particular, expected be powerful solution in context enzyme replacement therapy since enzymatic malfunction primary cause organelle dysfunction. Although several attempts have been made encapsulate within carrier vehicle,...
Abstract Fluid flow shear stresses are strong regulators for directing the organization of vascular networks. Knowledge structural and dynamics information within complex vasculature is essential tuning engineered tissues, by manipulating flows. However, reported investigations their associated over time limited, due to limitations in available physiological pre-clinical models, optical inaccessibility aseptic nature these models. Here, we developed laser speckle contrast imaging (LSCI)...
In order to fabricate functional organoids and microtissues, a high cell density is generally required. As such, the placement of suspensions in molds or microwells allow for concentration by sedimentation current standard production microtissues. Even though offer some level control over shape resulting microtissue, this limited as microtissues tend compact towards sphere after cells. 3D bioprinting on other hand offers complete structure. printing dense ink has been reported, extruding...
Bioprinting within support media has emerged as the superior alternative to conventional extrusion printing. Not only because it allows for more freedom over shapes that can be printed but also printing of inks would not retain shape fidelity in freeform deposition such watery liquids. Apart from functioning mechanical during embedded printing, hydrogel microparticle provide unique advantage offering distinct chemotactic cues cells baths by varying composition microparticles. There is great...
Abstract Dynamic growth factor presentation influences how individual endothelial cells assemble into complex vascular networks. Here, we developed programmable bioinks that facilitate dynamic VEGF to guide morphogenesis within 3D-bioprinted constructs. We leveraged aptamer’s high affinity for rapid sequestration in spatially confined regions and utilized aptamer-complementary sequence (CS) hybridization tune release kinetics temporally, days after bioprinting. show spatial resolution of...
Dynamic growth factor presentation influences how individual endothelial cells assemble into complex vascular networks. Here, programmable bioinks are developed that facilitate dynamic (VEGF) to guide morphogenesis within 3D-bioprinted constructs. Aptamer's high affinity is leveraged for rapid VEGF sequestration in spatially confined regions and utilized aptamer-complementary sequence (CS) hybridization tune release kinetics temporally, days after bioprinting. It shown spatial resolution of...
Abstract The functional principle behind extrusion‐based printing is the capability of flowing material through a nozzle on demand, which must solidify upon deposition, behavior exhibited only by some materials. Embedded offers solution to maintain shape fidelity during deposition wider range However, use moving in support bath can lead disturbance and spreading ink. In this study, novel embedded technique that eliminates need for employing magnetic sphere as plotting moiety introduced....